Oncostatin M (OSM) (NM_020530) Human Untagged Clone

CAT#: SC121421

OSM (untagged)-Human oncostatin M (OSM)


  "NM_020530" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol OSM
Synonyms MGC20461
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_020530 edited
GTCACCCCCAGCGGGCGCGGGCCGGAGCACGGGCACCCAGCATGGGGGTACTGCTCACAC
AGAGGACGCTGCTCAGTCTGGTCCTTGCACTCCTGTTTCCAAGCATGGCGAGCATGGCGG
CTATAGGCAGCTGCTCGAAAGAGTACCGCGTGCTCCTTGGCCAGCTCCAGAAGCAGACAG
ATCTCATGCAGGACACCAGCAGACTCCTGGACCCCTATATACGTATCCAAGGCCTGGATG
TTCCTAAACTGAGAGAGCACTGCAGGGAGCGCCCCGGGGCCTTCCCCAGTGAGGAGACCC
TGAGGGGGCTGGGCAGGCGGGGCTTCCTGCAGACCCTCAATGCCACACTGGGCTGCGTCC
TGCACAGACTGGCCGACTTAGAGCAGCGCCTCCCCAAGGCCCAGGATTTGGAGAGGTCTG
GGCTGAACATCGAGGACTTGGAGAAGCTGCAGATGGCGAGGCCGAACATCCTCGGGCTCA
GGAACAACATCTACTGCATGGCCCAGCTGCTGGACAACTCAGACACGGCTGAGCCCACGA
AGGCTGGCCGGGGGGCCTCTCAGCCGCCCACCCCCACCCCTGCCTCGGATGCTTTTCAGC
GCAAGCTGGAGGGCTGCAGGTTCCTGCATGGCTACCATCGCTTCATGCACTCAGTGGGGC
GGGTCTTCAGCAAGTGGGGGGAGAGCCCGAACCGGAGCCGGAGACACAGCCCCCACCAGG
CCCTGAGGAAGGGGGTGCGCAGGACCAGACCCTCCAGGAAAGGCAAGAGACTCATGACCA
GGGGACAGCTGCCCCGGTAGCCTCGAGAGCACCCCTTGCCGGTGAAGGATGCGGCAGGTG
CTCTGTGGATGAGAGGAACCATCGCAGGATGACAGCTCCCGGGTCCCCAAACCTGTTCCC
CTCTGCTACTAGCCACTGAGAAGTGCACTTTAAGAGGTGGGAGCTGGGCAGACCCCTCTA
CCTCCTCCAGGCTGGGAGACAGAGTCAGGCTGTTGCGCTCCCACCTCAGCCCCAAGTTCC
CCAGGCCCAGTGGGGTGGCCGGGCGGGCCACGCGGGACCGACTTTCCATTGATTCAGGGG
TCTGATGACACAGGCTGACTCATGGCCGGGCTGACTGCCCCCCTGCCTTGCTCCCCGAGG
CCTGCCGGTCCTTCCCTCTCATGACTTGCAGGGCCGTTGCCCCCAGACTTCCTCCTTTCC
GTGTTTCTGAAGGGGAGGTCACAGCCTGAGCTGGCCTCCTATGCCTCATCATGTCCCAAA
CCAGACACCTGGATGTCTGGGTGACCTCACTTTAGGCAGCTGTAACAGCGGCAGGGTGTC
CCAGGAGCCCTGATCCGGGGGTCCAGGGAATGGAGCTCAGGTCCCAGGCCAGCCCCGAAG
TCGCCACGTGGCCTGGGGCAGGTCACTTTACCTCTGTGGACCTGTTTTCTCTTTGTGAAG
CTAGGGAGTTAGAGGCTGTACAAGGCCCCCACTGCCTGTCGGTTGCTTGGATTCCCTGAC
GTAAGGTGGATATTAAAAATCTGTAAATCAGGACAGGTGGTGCAAATGGCGCTGGGAGGT
GTACACGGAGGTCTCTGTAAAAGCAGACCCACCTCCCAGCGCCGGGAAGCCCGTCTTGGG
TCCTCGCTGCTGGCTGCTCCCCCTGGTGGTGGATCCTGGAATTTTCTCACGCAGGAGCCA
TTGCTCTCCTAGAGGGGGTCTCAGAAACTGCGAGGCCAGTTCCTTGGAGGGACATGACTA
ATTTATCGATTTTTATCAATTTTTATCAGTTTTATATTTATAAGCCTTATTTATGATGTA
TATTTAATGTTAATATTGTGCAAACTTATATTTAAAACTTGCCTGGTTTCTAAAAAAAAA
AAAAAAAAA
>OriGene 5' read for NM_020530 unedited
GGTCAAACATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTCACCCCC
AGCGGGCGCGGGCCGNGACACGGGCACCCAGCATGGGGGTACTGCTCACACAGAGGACGC
TGCTCAGTCTGGTCCTTGCACTCCTGTTTCCAAGCATGGCGAGCATGGCGGCTATAGGCA
GCTGCTCGAAAGAGTACCGCGTGCTCCTTGGCCAGCTCCAGAAGCAGACAGATCTCATGC
AGGACACCAGCAGACTCCTGGACCCCTATATACGTATCCAAGGCCTGGATGTTCCTAAAC
TGAGAGAGCACTGCAGGGAGCGCCCCGGGGCCTTCCCCAGTGAGGAGACCCTGAGGGGGC
TGGGCAGGCGGGGCTTCCTGCAGACCCTCAATGCCACACTGGGCTGCGTCCTGCACAGAC
TGGCCGACTTAGAGCAGCGCCTCCCCAAGGCCCAGGATTTGGAGAGGTCTGGGCTGAACA
TCGAGGACTTGGAGAAGCTGCAGATGGCGAGGCCGAACATCCTCGGGCTCAGGAACAACA
TCTACTGCATGGCCCAGCTGCTGGACAACTCAGACACGGCTGAGCCCACGAAGGCTGGCC
GGGGGGCCTCTCAGCCGCCCACCCCCACCCCTGCCTCGGATGCTTTTCAGCGCAAGCTGG
ANGGCTGCAGGTTCCTGCATGGCTACCATCGCTTCATGCACTCAGTGGGGCGGGTCTTCA
GCAAGTGGGGGGAGAGCCCGACCCGGACCGGAGACACAGCCCCCACCAGGCCCTGAGGAA
GNGGGGTGCGCAGACCAGACCCTCCAGGAAAGGCAGAGACTCATGACCGGGGACAGCTGC
CCGGTAGCCTCGAGTTTTTTTTTTTTTTTTTCTTTGCCCGTTCCTTAATGGGGGAGGGCA
CAAGAAAAGCCTTCGCTCCCT
Restriction Sites Please inquire     
ACCN NM_020530
Insert Size 2300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_020530.3, NP_065391.1
RefSeq Size 1880 bp
RefSeq ORF 759 bp
Locus ID 5008
Cytogenetics 22q12.2
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Summary 'This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]'
Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).

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