WWP2 (NM_199424) Human Untagged Clone

CAT#: SC121839

WWP2 (untagged)-Human WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WWP2
• Synonyms: AIP2; WWp2-like
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_199424, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATCCAGGAACCAGCTCTGCCCCCAGGATGGGAGATGAAATACACCAGCGAGGGGGTGCGATACTTTG
  TGGACCACAATACCCGCACCACCACCTTTAAGGATCCTCGCCCGGGGTTTGAGTCGGGGACGAAGCAAGG
  TTCCCCTGGTGCTTATGACCGCAGTTTTCGGTGGAAGTATCACCAGTTCCGTTTCCTCTGCCATTCAAAT
  GCCCTACCTAGCCACGTGAAGATCAGCGTTTCCAGGCAGACGCTTTTCGAAGATTCCTTCCAACAGATCA
  TGAACATGAAACCCTATGACCTGCGCCGCCGGCTCTACATCATCATGCGTGGCGAGGAGGGCCTGGACTA
  TGGGGGCATCGCCAGAGAGTGGTTTTTCCTCCTGTCTCATGAGGTGCTCAACCCTATGTATTGTTTATTT
  GAATATGCCGGAAAGAACAATTACTGCCTGCAGATCAACCCCGCCTCCTCCATCAACCCGGACCACCTCA
  CCTACTTTCGCTTTATAGGCAGATTCATCGCCATGGCGCTGTACCATGGAAAGTTCATCGACACGGGCTT
  CACCCTCCCTTTCTACAAGCGGATGCTCAATAAGAGACCAACCCTGAAAGACCTGGAGTCCATTGACCCT
  GAGTTCTACAACTCCATTGTCTGGATCAAAGAGAACAACCTGGAAGAATGTGGCCTGGAGCTGTACTTCA
  TCCAGGACATGGAGATACTGGGCAAGGTGACGACCCACGAGCTGAAGGAGGGCGGCGAGAGCATCCGGGT
  CACAGAGGAGAACAAGGAAGAGTACATCATGCTGCTGACTGACTGGCGTTTCACCCGAGGCGTGGAAGAG
  CAGACCAAAGCCTTCCTGGATGGCTTCAACGAGGTGGCCCCGCTGGAGTGGCTGCGCTACTTTGACGAGA
  AAGAGCTGGAGCTGATGCTGTGCGGCATGCAGGAGATAGACATGAGCGACTGGCAGAAGAGCACCATCTA
  CCGGCACTACACCAAGAACAGCAAGCAGATCCAGTGGTTCTGGCAGGTGGTGAAGGAGATGGACAACGAG
  AAGAGGATCCGGCTGCTGCAGTTTGTCACCGGTACCTGCCGCCTGCCCGTCGGGGGATTTGCCGAACTCA
  TCGGTAGCAACGGACCACAGAAGTTTTGCATTGACAAAGTTGGCAAGGAAACCTGGCTGCCCAGAAGCCA
  CACCTGCTTCAACCGTCTGGATCTTCCACCCTACAAGAGCTACGAACAGCTGAGAGAGAAGCTGCTGTAT
  GCCATTGAGGAGACCGAGGGCTTTGGACAGGAGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_199424 unedited
  AAAGACAGGACAATGGACGGGTGTATTACGTGAACCATAACACTCGCACGACCCAGTGGG
  AGGATCCCCGGACCCAGGGGATGATCCAGGAACCAGCTCTGCCCCCAGGATGGGAGATGA
  AATACACCAGCGAGGGGGTGCGATACTTTGTGGACCACAATACCCGCACCACCACCTTTA
  AGGATCCTCGCCCGGGGTTTGAGTCGGGGACGAAGCAAGGTTCCCCTGGTGCTTATGACC
  GCAGTTTTCGGTGGAAGTATCACCAGTTCCGTTTCCTCTGCCATTCAAATGCCCTACCTA
  GCCACGTGAAGATCAGCGTTTCCAGGCAGACGCTTTTCGAAGATTCCTTCCAACAGATCA
  TGAACATGAAACCCTATGACCTGCGCCGCCGGCTCTACATCATCATGCGTGGCGAGGAGG
  GCCCTGGACTATGGGGGCATCGCCAGAGAGTGGTTTTTCCTCCTGTCTCACGAGGTGCTC
  AACCCTATGTATTGTTTATTTGAACATGCCCGAAAAGAACAATTACTCGCCTGCAGATAA
  AACCCCGCCTTCTTCATCAACCCCGGACAACCTCACCTACTTTGGTTTTATAGGCAAAAT
  TAATCGCCATGGCGCTGTACCATGGAAAGTTCATCGACACGTGCCTTACCCTTCCTTTTT
  AACAGCCGGATGCCCATAAGAGAACAACCCTTGAAAAACCGGAATCTTTGAACCTGAGTT
  TCAACACTCTTGGTCGGATCAAAAAAACAACCTCGTAAAATTGGGTCCTGAACCTTTCTT
  TTTCCCGCACATGAAATCCGGCCAAGGGCCCCCCACCATCTGAAGGAGCGGGGGAAACAT
  TTGGTCTCCGGTGGAAAAGTGAATATCCTTTCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_199424
• ORF Size: 1296 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_199424.1, NP_955456.1
• RefSeq Size: 3690
• RefSeq ORF: 1296
• Locus ID: 11060
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (WWP2-C) has a shorter N-terminus, compared to isoform 1.