VDAC3 (NM_005662) Human Untagged Clone

CAT#: SC122051

VDAC3 (untagged)-Human voltage-dependent anion channel 3 (VDAC3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VDAC3
• Synonyms: HD-VDAC3; VDAC-3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC122051 sequence for NM_005662 edited (data generated by NextGen Sequencing)
  ATGTGTAACACACCAACGTACTGTGACCTAGGAAAGGCTGCTAAGGATGTCTTCAACAAA
  GGATATGGCTTTGGCATGGTCAAGATAGACCTGAAAACCAAGTCTTGTAGTGGAGTGGAA
  TTTTCTACTTCTGGTCATGCTTACACTGATACAGGGAAAGCATCAGGCAACCTAGAAACC
  AAATATAAGGTCTGTAACTATGGACTTACCTTCACCCAGAAATGGAACACAGACAATACT
  CTAGGGACAGAAATCTCTTGGGAGAATAAGTTGGCTGAAGGGTTGAAACTGACTCTTGAT
  ACCATATTTGTACCGAACACAGGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGG
  GATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGC
  TGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCC
  AAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTG
  CACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAATGAG
  AAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTTGGC
  ATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAATGCC
  AGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTATCA
  GCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTTGAA
  CTGGAAGCTTAA
  
  Clone variation with respect to NM_005662.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005662 unedited
  ATTTTGTACTACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGAGCAGACCA
  GGCCCTCGGGGTGGAGGTCTTTGGTTTCATAAGAGCCTGAGAGAGATTTTTCTAAGATAT
  GTGTAACACACCAACGTACTGTGACCTAGGAAAGGCTGCTAAGGATGTCTTCAACAAAGG
  ATATGGCTTTGGCATGGTCAAGATAGACCTGAAAACCAAGTCTTGTAGTGGAGTGGAATT
  TTCTACTTCTGGTCATGCTTACACTGATACAGGGAAAGCATCAGGCAACCTAGAAACCAA
  ATATAAGGTCTGTAACTATGGACTTACCTTCACCCAGAAATGGAACACAGACAATACTCT
  AGGGACAGAAATCTCTTGGGAGAATAAGTTGGCTGAAGGGTTGAAACTGACTCTTGATAC
  CATATTTGTACCGAACACAGGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAACGGGA
  TTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTATGGCTG
  GGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACAGCCAA
  ATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAGCTGCA
  CACACATGTGAACGATGGCACTGAATTTGGGAGGTTCTATCTACCACGAAGGTGAATGAG
  AAAGATTGAAACATCCATAAACCTTGCTTGGACGCTTGGGAGTAACACACCCGGTNTTGC
  ATTGTTGCTAAGACATGCCTGAATGGAAAACTTTCTTCTCTGCTAAGTAATAATGCACCC
  TGATGGACCTGGTTTATCCCACACCTTCGACCAGAGCCAAATGCTTTACAGCTAATCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005662 unedited
  GAGTTTTTTTTTCGGGTTTTTTTTTTATGTTCCAAATGTGATGGGTTTATTTTATTTTAC
  TATGATGCAAAACCAAAGATTCCACTATAGCACAGAGACCAGTATATTACAAGGTCATGA
  AAAAATGGTGTGGGACATGCAGGACGTGATGTACAAACTGGTGGGTCAGATCGTCTCCTC
  TAACATGACGCTACACTGTCGCTGAGGAACACATTTAATAACACTTCAGAACTGAACTGA
  AACGTGGCACAAACATGACAACTTCCAGGCATGCCTTCAAGCATCTCCCTCAGGAGGGAT
  TCGCAACCCCTAGACTTCAGTGTGGGGAGGATTACAATTCTTTGGAAGAATAAAAAGTTC
  ACACTTTTGAAATTTCACAGAAGAATTTTAAGGCCAAAACATAGTGGGTTCATTTCTCTT
  CACTTCCAGGGACAAATCTGATGCTTTCCTCAAACCACATTAAGCTTCCAGTTCAAATCC
  CAAGCCAACCTTGTGACCTCCTGCACTGAAGTTCTTTCCATCGATTAAAGCTGATAAAGT
  CAATTTGACTCCTGGGTCGAGGTTCTGAGTATAACCCATTCCATCAGGCTGGCATATTAC
  TTTACAGAAGAGAAGTCTTCCTTCCACTGTACTTACCACATGCAAAACGGTGTGTTCTCC
  ACTGTCAACCAGTTATGAGGTCAACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005662
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005662.3, NP_005653.3
• RefSeq Size: 1414 bp
• RefSeq ORF: 852 bp
• Locus ID: 7419
• Cytogenetics: 8p11.21
• Domains: Euk_porin
• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Calcium signaling pathway, Huntington's disease, Parkinson's disease
• Gene Summary: 'This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]'
  Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1.