TRPV4 (NM_147204) Human Untagged Clone

CAT#: SC122052

TRPV4 (untagged)-Human transient receptor potential cation channel, subfamily V, member 4 (TRPV4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPV4
• Synonyms: BCYM3; CMT2C; HMSN2C; OTRPC4; SMAL; SPSMA; SSQTL1; TRP12; VRL2; VROAC
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC122052 sequence for NM_147204 edited (data generated by NextGen Sequencing)
  ATGGCGGATTCCAGCGAAGGCCCCCGCGCGGGGCCCGGGGAGGTGGCTGAGCTCCCCGGG
  GATGAGAGTGGCACCCCAGGTGGGGAGGCTTTTCCTCTCTCCTCCCTGGCCAATCTGTTT
  GAGGGGGAGGATGGCTCCCTTTCGCCCTCACCGGCTGATGCCAGTCGCCCTGCTGGCCCA
  GGCGATGGGCGACCAAATCTGCGCATGAAGTTCCAGGGCGCCTTCCGCAAGGGGGTGCCC
  AACCCCATCGATCTGCTGGAGTCCACCCTATATGAGTCCTCGGTGGTGCCTGGGCCCAAG
  AAAGCACCCATGGACTCACTGTTTGACTACGGCACCTATCGTCACCACTCCAGTGACAAC
  AAGAGGTGGAGGAAGAAGATCATAGAGAAGCAGCCGCAGAGCCCCAAAGCCCCTGCCCCT
  CAGCCGCCCCCCATCCTCAAAGTCTTCAACCGGCCTATCCTCTTTGACATCGTGTCCCGG
  GGCTCCACTGCTGACCTGGACGGGCTGCTCCCATTCTTGCTGACCCACAAGAAACGCCTA
  ACTGATGAGGAGTTTCGAGAGCCATCTACGGGGAAGACCTGCCTGCCCAAGGCCTTGCTG
  AACCTGAGCAATGGCCGCAACGACACCATCCCTGTGCTGCTGGACATCGCGGAGCGCACC
  GGCAACATGCGGGAGTTCATTAACTCGCCCTTCCGTGACATCTACTATCGAGGTCAGACA
  GCCCTGCACATCGCCATTGAGCGTCGCTGCAAACACTACGTGGAACTTCTCGTGGCCCAG
  GGAGCTGATGTCCACGCCCAGGCCCGTGGGCGCTTCTTCCAGCCCAAGGATGAGGGGGGC
  TACTTCTACTTTGGGGAGCTGCCCCTGTCGCTGGCTGCCTGCACCAACCAGCCCCACATT
  GTCAACTACCTGACGGAGAACCCCCACAAGAAGGCGGACATGCGGCGCCAGGACTCGCGA
  GGCAACACAGTGCTGCATGCGCTGGTGGCCATTGCTGACAACACCCGTGAGAACACCAAG
  TTTGTTACCAAGATGTACGACCTGCTGCTGCTCAAGTGTGCCCGCCTCTTCCCCGACAGC
  AACCTGGAGGCCGTGCTCAACAACGACGGCCTCTCGCCCCTCATGATGGCTGCCAAGACG
  GGCAAGATTGGGAACCGCCACGAGATGCTGGCTGTGGAGCCCATCAATGAACTGCTGCGG
  GACAAGTGGCGCAAGTTCGGGGCCGTCTCCTTCTACATCAACGTGGTCTCCTACCTGTGT
  GCCATGGTCATCTTCACTCTCACCGCCTACTACCAGCCGCTGGAGGGCACACCGCCGTAC
  CCTTACCGCACCACGGTGGACTACCTGCGGCTGGCTGGCGAGGTCATTACGCTCTTCACT
  GGGGTCCTGTTCTTCTTCACCAACATCAAAGACTTGTTCATGAAGAAATGCCCTGGAGTG
  AATTCTCTCTTCATTGATGGCTCCTTCCAGCTGCTCTACTTCATCTACTCTGTCCTGGTG
  ATCGTCTCAGCAGCCCTCTACCTGGCAGGGATCGAGGCCTACCTGGCCGTGATGGTCTTT
  GCCCTGGTCCTGGGCTGGATGAATGCCCTTTACTTCACCCGTGGGCTGAAGCTGACGGGG
  ACCTATAGCATCATGATCCAGAAGATTCTCTTCAAGGACCTTTTCCGATTCCTGCTCGTC
  TACTTGCTCTTCATGATCGGCTACGCTTCAGCCCTGGTCTCCCTCCTGAACCCGTGTGCC
  AACATGAAGGTGTGCAATGAGGACCAGACCAACTGCACAGTGCCCACTTACCCCTCGTGC
  CGTGACAGCGAGACCTTCAGCACCTTCCTCCTGGACCTGTTTAAGCTGACCATCGGCATG
  GGCGACCTGGAGATGCTGAGCAGCACCAAGTACCCCGTGGTCTTCATCATCCTGCTGGTG
  ACCTACATCATCCTCACCTTTGTGCTGCTCCTCAACATGCTCATTGCCCTCATGGGCGAG
  ACAGTGGGCCAGGTCTCCAAGGAGAGCAAGCACATCTGGAAGCTGCAGTGGGCCACCACC
  ATCCTGGACATTGAGCGCTCCTTCCCCGTATTCCTGAGGAAGGCCTTCCGCTCTGGGGAG
  ATGGTCACCGTGGGCAAGAGCTCGGACGGCACTCCTGACCGCAGGTGGTGCTTCAGGGTG
  GATGAGGTGAACTGGTCTCACTGGAACCAGAACTTGGGCATCATCAACGAGGACCCGGGC
  AAGAATGAGACCTACCAGTATTATGGCTTCTCGCATACCGTGGGCCGCCTCCGCAGGGAT
  CGCTGGTCCTCGGTGGTACCCCGCGTGGTGGAACTGAACAAGAACTCGAACCCGGACGAG
  GTGGTGGTGCCTCTGGACAGCATGGGGAACCCCCGCTGCGATGGCCACCAGCAGGGTTAC
  CCCCGCAAGTGGAGGACTGATGACGCCCCGCTCTAG
  
  Clone variation with respect to NM_147204.2
  670 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_147204 unedited
  GATATTTGTAATCACGACTTCACTATAGGGCGGCACGCGCAATTCGGCACGAGGTACCCT
  GGTACTCCATCACTAACCTGCTGTGTGACCTCAGGCTGAGCAGTGCAGACGGGCCTGGGG
  CAGGCATGGCGGATTCCAGCGAAGGCCCCCGCGCGGGGCCCGGGGAGGTGGCTGAGCTCC
  CCGGGGATGAGAGTGGCACCCCAGGTGGGGAGGCTTTTCCTCTCTCCTCCCTGGCCAATC
  TGTTTGAGGGGGAGGATGGCTCCCTTTCGCCCTCACCGGCTGATGCCAGTCGCCCTGCTG
  GCCCAGGCGATGGGCGACCAAATCTGCGCATGAAGTTCCAGGGCGCCTTCCGCAAGGGGG
  TGCCCAACCCCATCGATCTGCTGGAGTCCACCCTATATGAGTCCTCGGTGGTGCCTGGGC
  CCAAGAAAGCACCCATGGACTCACTGTTTGACTACGGCACCTATCGTCACCACTCCAGTG
  ACAACAAGAGGTGGAGGAAGAAGATCATAGAGAAGCAGCCGCAGAGCCCCAAAGCCCCTG
  CCCCTCAGCCGCCCCCCATCCTCAAAGTCTTCAACCGGCCTATCCTCTTTGACATCGTGT
  CCCGGNGCTCCACTGCTGACCTGGACGGGCTGCTCCCATTCTTGCTGACCCANCAGAAAC
  GCCTAACTGATGANGAGTTNCGAGAGCCATCTACGGGGAAGACCTGCCTGCCCAAGGCCT
  TTGCTGACCTGAGCAATGGCCGCNACGACACCATCCCNTGTGCTGCTGGACATCGCGNAG
  CGCCACGGGCACATGCNGGAGTTCATTACTCGCCCTTTCGTGACTCTACTTTCGAGTCAG
  ACAGCCCTGCCATCGCCATGAACGTCGCTGCAACACTACGTGGAACTTCTCGTGCCCAGG
  AAGCTGATGTCCACGCCAAGCCCTGGGCGCCTTTTCCACCCCAGGTGAAGGGGGCTACCT
  CTACTTTGGNACCTGCCCCTGTCCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_147204 unedited
  TTACTTTGGACNCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTCAATGAA
  TAAACATTTATTGAGCACCGGCAAATCCCAGACACTACAGAACACACAGAAGGCATGGCC
  CCACGCCGAGGGCCCCAGCCCCTTGCAAAGCTGCCACGCTGCCAAAAATGGTGGCGCATG
  CAGCTCAGGCGCAGGCTGAGGCTGGGGCTTGGCCGGGCAGTGCACTTGGAACGGGGTCCT
  AAGGCCTCTGCCAGGTTCCAGCTGGGGCAGGGGTCACGTCGCTTCCTGAGAGCAGAGCAA
  ATAAATAATGGAGAGGCAGGGGCTGGGGCCTGAGGTGGAGGGGCTCTGGCGTTGGCTTAT
  GTGACTCCATAGGAGCAAGACAGGTGGCCGGGAGCCCCCACCCCAGGGTGGGGAGGCAGA
  GCCACGGGACCACAGGGTCCTGGGGCCTCCCTGGCACCTCCACTGGTCCCTCGCCTCTGG
  GGCCAAAGCAGGGTGTGGGGGGACACCCCAGAAGGCACTGCTGAAATGCGGCTGGACTAG
  AAATGAGTGGGCAGAGAAGCTGGGGCTGGGCTGCAGTCCCTAGAGCGGGGCGTCATCAGT
  CCTCCACTTGCGGGGGTAACCCTGCTGGTGGCCATCGCAGCGGGGGTTCCCCATGCTGTC
  CAGAGGCACCACCACCTCGTCCGGGTTCGAGTTCTTGTTCAGTTCCACCACGCGGNGTAC
  CACCGAGGACCAGCGATCCCTGCGGAGGCGGCCCACGGTATGCGAGAAGCCATAATACTG
  GTAGGTCTCATTCTTGCCCGGGTCCTCGTTGATGATGCCCAAGTTCTGGTTCCAGTGAGA
  CCAGTTCACCTCATCCACCCTGAAGCACACCTGTCGTCAGAAGTGCCGTCCGAGCTTTGC
  CCACGGTGACATCTCCCAGACGGAAGCCTTCTCAGAATACGGGAAGAGCGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_147204
• ORF Size: 2436 bp
• Insert Size: 3150
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_147204.1, NP_671737.1
• RefSeq Size: 3057
• RefSeq ORF: 2436
• Locus ID: 59341
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Gene Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in an isoform (b) that lacks an internal segment compared to isoform a.