PTPRN (BC007713) Human Untagged Clone

CAT#: SC122253

PTPRN (untagged)-Homo sapiens, protein tyrosine phosphatase, receptor type, N, clone MGC:12646 IMAGE:4130827, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRN
• Synonyms: FLJ16131; IA-2; IA-2/PTP; IA2; ICA512; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase-like N; R-PTP-N
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC007713 edited
  GGCACGAGGGCCAGCTCCTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTG
  GAGCACCTGCTGCTGCCCCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTG
  CTGCAGCCCTACCTGTTCCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGC
  TCCCCAGGGATGGTCAGTGTCGGCCCCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGC
  AGAACTGCCTCCAAGGGCATATTTGGGGACCACCCTGGCCACTCCTACGGGGACCTTCCA
  GGGCCTTCACCTGCCCAGCTTTTTCAAGACTCTGGGCTGCTCTATCTGGCCCAGGAGTTG
  CCAGCACCCAGCAGGGCCAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCCGGGCA
  GAGGACTCCCCAGAGGGCTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCT
  TCCCCAGCTGTGCAGCCAGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTAT
  GGGGTAGAGCTGCGTCAGCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAG
  CTACTGCCCAAGGGTGCAGGAAGAAATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATC
  AAGAAAACAATGGAGGGGCCGGTGGAGGGCAGAGACACAGCAGAGCTTCCAGCCCGCACA
  TCCCCCATGCCTGGACACCCCACTGCCAGCCCTACCTCCAGTGAAGTCCAGCAGGTGCCA
  AGCCCTGTCTCCTCTGAGCCTCCCAAAGCTGCCAGACCCCCTGTGACACCTGTCCTGCTA
  GAGAAGAAAAGCCCACTGGGCCAGAGCCAGCCCACGGTGGCAGGACAGCCCTCAGCCCGC
  CCAGCAGCAGAGGAATATGGCTACATCGTCACTGATCAGAAGCCCCTGAGCCTGGCTGCA
  GGAGTGAAGCTGCTGGAGATCCTGGCTGAGCATGTGCACATGTCCTCAGGCAGCTTCATC
  AACATCAGTGTGGTGGGACCAGCCCTCACCTTCCGCATCCGGCACAATGAGCAGAACCTG
  TCTTTGGCTGATGTGACCCAACAAGCAGGGCTGGTGAAGTCTGAACTGGAAGCACAGACA
  GGGCTCCAAATCTTGCAGACAGGAGTGGGACAGAGGGAGGAGGCAGCTGCAGTCCTTCCC
  CAAACTGCGCACAGCACCTCACCCATGCGCTCAGTGCTGCTCACTCTGGTGGCCCTGGCA
  GGTGTGGCTGGGCTGCTGGTGGCTCTGGCTGTGGCTCTGTGTGTGCGGCAGCATGCGCGG
  CAGCAAGACAAGGAGCGCCTGGCAGCCCTGGGGCCTGAGGGGGCCCATGGTGACACTACC
  TTTGAGTACCAGGACCTGTGCCGCCAGCACATGGCCACGAAGTCCTTGTTCAACCGGGCA
  GAGGGTCCACCGGAGCCTTCACGGGTGAGCAGTGTGTCCTCCCAGTTCAGCGACGCAGCC
  CAGGCCAGCCCCAGCTCCCACAGCAGCACCCCGTCCTGGTGCGAGGAGCCGGCCCAAGCC
  AACATGGACATCTCCACGGGACACATGATTCTGGCATACATGGAGGATCACCTGCGGAAC
  CGGGACCGCCTTGCCAAGGAGTGGCAGGCCCTCTGTGCCTACCAAGCAGAGCCAAACACC
  TGTGCCACCGCGCAGGGGGAGGGCAACATCAAAAAGAACCGGCATCCTGACTTCCTGCCC
  TATGACCATGCCCGCATAAAACTGAAGGTGGAGAGCAGCCCTTCTCGGAGCGATTACATC
  AACGCCAGCCCCATTATTGAGCATGACCCTCGGATGCCAGCCTACATAGCCACGCAGGGC
  CCGCTGTCCCATACCATCGCAGACTTCTGGCAGATGGTGTGGGAGAGCGGCTGCACCGTC
  ATCGTCATGCTGACCCCGCTGGTGGAGGATGGTGTCAAGCAGTGTGACCGCTACTGGCCA
  GATGAGGGTGCCTCCCTCTACCACGTATATGAGGTGAACCTGGTGTCGGAGCACATCTGG
  TGCGAGGACTTTCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGC
  ACGCTCACGCAGTTCCACTTCCTCAGCTGGCCGGCAGAGGGCACACCGGCCTCCACGCGG
  CCCCTGCTGGACTTCCGCAGGAAGGTGAACAAGTGCTACCGGGGCCGCTCCTGCCCCATC
  ATCGTGCACTGCAGTGATGGTGCGGGGAGGACCGGCACCTACATCCTCATCGACATGGTC
  CTGAACCGCATGGCAAAAGGAGTGAAGGAGATTGACATCGCTGCCACCCTGGAGCATGTC
  CGTGACCAGCGGCCTGGCCTTGTCCGCTCTAAGGACCAGTTTGAATTTGCCCTGACAGCC
  GTGGCGGAGGAAGTGAATGCCATCCTCAAGGCCCTGCCCCAGTGAGACCCTGGGGCCCCT
  TGGCGGGCAGCCCAGCCTCTGTCCCTCTTTGCCTGTGTGAGCATCTCTGTGTACCCACTC
  CTCACTGCCCCACCAGCCACCTCTTGGGCATGCTCAGCCCTTCCTAGAAGAGTCAGGAAG
  GGAAAGCCAGAAGGGGCACGCCTGCCCAGCCTCGCATGCCAGAGCCTGGGGCATCCCAGA
  GCCCAGGGCATCCCATGGGGGTGCTGCAGCCAGGAGGAGAGGAAAGGACATGGGTAGCAA
  TTCTACCCAGAGCCTTCTCCTGCCTACATTCCCTGGCCTGGCTCTCCTGTAGCTCTCCTG
  GGGTTCTGGGAGTTCCCTGAACATCTGTGTGTGTCCCCCTATGCTCCAGTATGGAAGAAT
  GGGGTGGAGGGTCGCCACACCCGGCTCCCCCTGCTTCTCAGCCCCGGGCCTGCCTCTGAC
  TCACACTTGGGCGCTCTGCCCTCCCTGGCCTCACGCCCAGCCTCCTCCCACCACCCTCCC
  ACCATGCGCTGCTCAACCTCTCTCCTTCTGGCGCAAGAGAACATTTCTAGAAAAAACTAC
  TTTTGTACCAGTGTGAATAAAGTTAGTGTGTTGTCTGTGCAGCTGCAAAAAAAAAAAAAA
  AAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC007713 unedited
  NGGTTCAGATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCCAGCTC
  CTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTGGAGCACCTGCTGCTGCC
  CCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTGCTGCAGCCCTACCTGTT
  CCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGCTCCCCAGGGATGGTCAG
  TGTCGGCCCCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGCAGAACTGCCTCCAAGGG
  CATATTTGGGGACCACCCTGGCCACTCCTACGGGGACCTTCCAGGGCCTTCACCTGCCCA
  GCTTTTTCAAGACTCTGGGCTGCTCTATCTGGCCCAGGAGTTGCCAGCACCCAGCAGGGC
  CAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCCGGGCAGAGGACTCCCCAGAGGG
  CTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCTTCCCCAGCTGTGCAGCC
  AGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTATGGGGTAGAGCTGCGTCA
  GCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAGCTACTGCCCAAGGGTGC
  ANGAAGAAATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATCAAGAAAACAATGGAGGG
  GCCGGTGGAGGGCAAANACACAGCAGAGCTTCCAGCCCGCACATCCCCCATGCCTGGACA
  CCCCACTGCCAGCCCTACCTCCAGTGAAGTCCCAGCAGTGCCAAGCCCTGTCTCCTCTGA
  GCCTCCAAAGCTGCCAGACCCCTGTGACACCTGTCCTGCTAGAGAAGAAAAGCCACTGGG
  CCAAC
  
• Restriction Sites: Please inquire
• ACCN: BC007713
• Insert Size: 3065 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC007713.1, AAH07713.1
• RefSeq Size: 3065 bp
• Locus ID: 5798
• Cytogenetics: 2q35
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Type I diabetes mellitus
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]'