IL24 (BC009681) Human Untagged Clone

CAT#: SC122294

IL24 (untagged)-Human interleukin 24, transcript variant 1 (cDNA clone MGC:8926 IMAGE:3878467), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL24
• Synonyms: C49A; FISP; IL-24; IL-24 splice variant delE3; IL-24 splice variant delE5; IL10B; Interleukin 24; mda-7; MDA7; melanoma differentiation association protein 7; Mob-5; OTTHUMP00000034620; ST16; suppression of tumorigenicity 16 (melanoma differentiation)
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC009681 edited
  ATGACTTCCACGGCTGGGACGGGAACCTTCCACCCACAGCTATGCCTCTGATTGGTGAAT
  GGTGAAGGTGCCTGTCTAACTTTTCTGTAAAAAGAACCAGCTGCCTCCAGGCAGCCAGCC
  CTCAAGCATCACTTACAGGACCAGAGGGACAAGACATGACTGTGATGAGGAGCTGCTTTC
  GCCAATTTAACACCAAGAAGAATTGAGGCTGCTTGGGAGGAAGGCCAGGAGGAACACGAG
  ACTGAGAGATGAATTTTCAACAGAGGCTGCAAAGCCTGTGGACTTTAGCCAGCAGACCCT
  TCTGCCCTCCTTTGCTGGCGACAGCCTCTCAAATGCAGATGGTTGTGCTCCCTTGCCTGG
  GTTTTACCCTGCTTCTCTGGAGCCAGGTATCAGGGGCCCAGGGCCAAGAATTCCACTTTG
  GGCCCTGCCAAGTGAAGGGGGTTGTTCCCCAGAAACTGTGGGAAGCCTTCTGGGCTGTGA
  AAGACACTATGCAAGCTCAGGATAACATCACGAGTGCCCGGCTGCTGCAGCAGGAGGTTC
  TGCAGAACGTCTCGGATGCTGAGAGCTGTTACCTTGTCCACACCCTGCTGGAGTTCTACT
  TGAAAACTGTTTTCAAAAACTACCACAATAGAACAGTTGAAGTCAGGACTCTGAAGTCAT
  TCTCTACTCTGGCCAACAACTTTGTTCTCATCGTGTCACAACTGCAACCCAGTCAAGAAA
  ATGAGATGTTTTCCATCAGAGACAGTGCACACAGGCGGTTTCTGCTATTCCGGAGAGCAT
  TCAAACAGTTGGACGTAGAAGCAGCTCTGACCAAAGCCCTTGGGGAAGTGGACATTCTTC
  TGACCTGGATGCAGAAATTCTACAAGCTCTGAATGTCTAGACCAGGACCTCCCTCCCCCT
  GGCACTGGTTTGTTCCCTGTGTCATTTCAAACAGTCTCCCTTCCTATGCTGTTCACTGGA
  CACTTCACGCCCTTGGCCATGGGTCCCATTCTTGGCCCAGGATTATTGTCAAAGAAGTCA
  TTCTTTAAGCAGCGCCAGTGACAGTCAGGGAAGGTGCCTCTGGATGCTGTGAAGAGTCTA
  CAGAGAAGATTCTTGTATTTATTACAACTCTATTTAATTAATGTCAGTATTTCAACTGAA
  GTTCTATTTATTTGTGAGACTGTAAGTTACATGAAGGCAGCAGAATATTGTGCCCCATGC
  TTCTTTACCCCTCACAATCCTTGCCACAGTGTGGGGCAGTGGATGGGTGCTTAGTAAGTA
  CTTAATAAACTGTGGTGCTTTTTTTGGCCTGTCAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC009681 unedited
  CCGGAGTTAGTACGCCTGGGGATCCTTCCCGCTGTTTTGACCTCCATAGAAGAACCGGGA
  CCGATCCAGCCTCCGGGATCTAGCCTGAGGGCGCGGGACGGATAACAATTTCACACAGGA
  AACAGCTATGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAG
  CAGGCTGGTACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGATGACTTCC
  ACGGGTGGGACGGGAACCTTCCACCCACAGCTATGCCTCTGATTGGTGAATGGTGAAGGT
  GCCTGTCTAACTTTTCTGTAAAAAGAACCAGCTGCCTCCAGGCAGCCAGCCCTCAAGCAT
  CACTTACAGGACCAGAGGGACAAGACATGACTGTGATGAGGAGCTGCTTTCGCCAATTTA
  ACACCAAGAAGAATTGAGGCTGCTTGGGAGGAAGGCCANGAGGAACACGAGACTGAGAGA
  TGAATTTTCAACAGAGGCTGCAAAGCCTGTGGACTTTAGCCAGCAGACCCTTCTGCCCTC
  CTTTGCTGGCGACAGCCTCTCAAATGCAGATGGTTGTGCTCCCTTGCCTGCGTTTTACCC
  TGGTTCTCTGGAGCCAGGTATCAAGGGCCCACGGCCAAGAATTCCACTTTGGGCCCTGCC
  ACATGAAAGGGGTTGTTCCCCAGAAACTGGGGGAAGCCTTCTGGGCTGGGAAAGACACTA
  TGCACGCTCAGGATAACATCCCAAGTGCCCGGCTGCTGAACCAGGAGGTTCTGCAGAACC
  TCTCGGATGCTGAAGAGCTGTACCTTGGCCACACCCGGTTGGAGTTCTATTGAAAACGGT
  TTCAAAACTACCCCAATAGAACAGTGGAGGGAGGGACTTTAAATCCTTGTTCTATCTGGC
  GAAAN
  
• Restriction Sites: Please inquire
• ACCN: BC009681
• Insert Size: 1309
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC009681.1, AAH09681.1
• RefSeq Size: 1309
• Locus ID: 11009
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]