TGM1 (NM_000359) Human Untagged Clone

CAT#: SC122560

TGM1 (untagged)-Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TGM1
• Synonyms: ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000359 edited
  CTGTCCCATCCATCCTGACCTGTTCCATCTCAGCCCCAGGACTCAGTACTGCGGTTGCCA
  ACACTGCTGCCAGGCATGATGGATGGGCCACGTTCCGATGTGGGCCGTTGGGGTGGCAAC
  CCCTTGCAGCCCCCTACCACGCCATCTCCAGAGCCAGAGCCAGAGCCAGACGGACGCTCT
  CGCAGAGGAGGAGGCCGTTCCTTCTGGGCTCGCTGCTGTGGCTGCTGTTCATGCCGAAAT
  GCGGCAGATGACGACTGGGGACCTGAACCCTCTGACTCCAGGGGTCGAGGGTCCAGCTCT
  GGCACTCGAAGACCTGGCTCCCGGGGCTCAGACTCCCGCCGGCCTGTATCCCGGGGCAGC
  GGTGTCAATGCAGCTGGAGATGGCACCATCCGAGAGGGCATGCTAGTAGTGAACGGTGTG
  GACTTGCTGAGCTCGCGCTCGGACCAGAACCGCCGAGAGCACCACACAGACGAGTATGAG
  TACGACGAGCTGATAGTGCGCCGCGGGCAGCCTTTCCATATGCTCCTCCTCCTGTCCCGG
  ACCTATGAATCCTCTGATCGCATCACCCTTGAGTTACTCATCGGAAACAACCCCGAGGTG
  GGCAAGGGCACGCACGTGATCATCCCAGTGGGCAAGGGGGGCAGTGGAGGCTGGAAAGCC
  CAGGTGGTCAAGGCCAGTGGGCAGAATCTGAACCTGCGGGTCCACACTTCCCCCAACGCC
  ATCATCGGCAAGTTTCAGTTCACAGTCCGCACACAATCAGACGCTGGGGAGTTCCAGTTG
  CCCTTTGACCCCCGCAATGAGATCTACATCCTCTTCAACCCCTGGTGCCCAGAGGACATT
  GTGTACGTGGACCATGAGGATTGGCGGCAGGAGTATGTTCTTAATGAGTCTGGGAGAATT
  TACTACGGGACCGAAGCACAGATTGGTGAGCGGACCTGGAACTACGGCCAGTTTGACCAC
  GGGGTGCTGGATGCCTGCTTATACATCCTGGACCGGCGGGGGATGCCATATGGAGGCCGT
  GGAGACCCAGTCAATGTCTCCCGGGTCATCTCTGCCATGGTGAACTCCCTGGATGACAAT
  GGAGTCCTGATTGGGAACTGGTCTGGTGATTACTCCCGAGGCACCAACCCATCAGCGTGG
  GTGGGCAGCGTGGAGATCCTGCTTAGCTACCTACGCACGGGATATTCCGTCCCCTATGGC
  CAGTGCTGGGTCTTTGCTGGCGTGACCACCACAGTGCTGCGCTGCCTGGGTCTGGCCACC
  CGTACTGTCACCAACTTCAACTCCGCCCACGACACAGACACATCCCTTACCATGGACATC
  TACTTCGACGAGAACATGAAGCCCCTGGAGCACCTGAACCATGATTCTGTCTGGAACTTC
  CATGTGTGGAACGACTGCTGGATGAAGAGGCCGGATCTGCCCTCGGGCTTTGATGGGTGG
  CAGGTGGTGGATGCCACACCCCAAGAGACTAGCAGTGGCATCTTCTGCTGCGGCCCCTGC
  TCTGTGGAGTCCATCAAGAATGGCCTGGTCTACATGAAGTACGACACGCCTTTCATTTTT
  GCTGAGGTGAATAGTGACAAGGTGTACTGGCAGCGGCAGGATGATGGCAGCTTCAAGATT
  GTTTATGTGGAGGAGAAGGCCATCGGCACACTCATTGTCACAAAGGCCATCAGCTCCAAC
  ATGCGGGAGGACATCACCTACCTCTATAAGCACCCAGAAGGCTCAGACGCAGAGCGGAAG
  GCAGTAGAGACAGCAGCAGCCCACGGCAGCAAACCCAATGTGTATGCCAACCGGGGCTCA
  GCGGAGGATGTGGCCATGCAGGTGGAGGCACAGGACGCGGTGATGGGGCAGGATCTGATG
  GTCTCTGTGATGCTGATCAATCACAGCAGCAGCCGCCGCACAGTGAAACTGCACCTCTAC
  CTCTCAGTCACTTTCTATACTGGTGTCAGTGGTACCATCTTCAAGGAGACCAAGAAGGAA
  GTGGAGCTGGCACCAGGGGCCTCGGACCGTGTGACCATGCCAGTGGCCTACAAGGAATAC
  CGGCCCCATCTTGTGGACCAGGGGGCCATGCTGCTCAATGTCTCAGGCCACGTCAAGGAG
  AGCGGGCAGGTGCTGGCCAAGCAGCACACCTTCCGTCTGCGCACCCCAGACCTCTCCCTC
  ACGTTACTGGGAGCAGCAGTGGTTGGCCAGGAGTGTGAAGTACAGATTGTCTTCAAGAAC
  CCCCTTCCCGTCACCCTCACCAATGTCGTCTTCCGGCTCGAAGGCTCTGGGTTACAGAGG
  CCCAAGATCCTCAACGTTGGGGACATTGGAGGCAATGAAACAGTGACACTGCGCCAGTCG
  TTTGTGCCTGTGCGACCAGGCCCCCGCCAGCTCATTGCCAGCTTGGACAGCCCACAGCTC
  TCCCAGGTGCACGGTGTCATCCAGGTGGATGTGGCCCCAGCCCCTGGGGATGGGGGCTTC
  TTCTCAGACGCTGGAGGTGACAGTCACTTAGGAGAGACCATCCCTATGGCATCTCGAGGT
  GGAGCTTAGCCCTGTGCCAGGAGCAATGGGACTGGAGTCAGATGAGCAAGGACATTGCCC
  CAAGATAGGGGCACACTACAGAGCAGCTCCCCAGGAGCTCAGGTGGGGAGTCCAGGGCTC
  CCGGAGAGGGAGTCAGTCTTCACTTGCACTGGGGGAACAGATGCTAATAAACTGTTTTTT
  AATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000359 unedited
  NNNGGTTTGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCCCGGGATCTGTCCCA
  TCCATCCTGACCTGTTCCATCTCAGCCCCAGGACTCAGTACTGCGGTTGCCAACACTGCT
  GCCAGGCATGATGGATGGGCCACGTTCCGATGTGGGCCGTTGGGGTGGCAACCCCTTGCA
  GCCCCCTACCACGCCATCTCCAGAGCCAGAGCCAGAGCCAGACGGACGCTCTCGCAGAGG
  AGGAGGCCGTTCCTTCTGGGCTCGCTGCTGTGGCTGCTGTTCATGCCGAAATGCGGCAGA
  TGACGACTGGGGACCTGAACCCTCTGACTCCAGGGGTCGAGGGTCCAGCTCTGGCACTCG
  AAGACCTGGCTCCCGGGGCTCAGACTCCCGCCGGCCTGTATCCCGGGGCAGCGGTGTCAA
  TGCAGCTGGAGATGGCACCATCCGAGAGGGCATGCTAGTAGTGAACGGTGTGGACTTGCT
  GAGCTCGCGCTCGGACCAGAACCGCCGAGAGCACCACACAGACGAGTATGAGTACGACGA
  GCTGATAGTGCGCCGCGGGCAGCCTTTCCATATGCTCCTCCTCCTGTCCCGGACCTATGA
  ATCCTCTGATCGCATCACCCTTGAGTTACTCATCGGAAACAACCCCGAGGTGGGCAAGGG
  CACGCACGTGATCATCCCAGTGGGCAAGGGGGGCAGTGGAGGCTGGAAAGCCCAGGTGGT
  CAAGGCCAGTGGGCAGAATCTGAACCTGCGGGTCCACACTTCCCCCAACGCCATCATCGG
  GCAGTTTCAGTTCACAGTCCGCACACAATCAGACGCTGGGGAGTTCCAGTTGCCCCTTTG
  ACCCCGCAATGAGATCTACATCCTCTTCAACCCTGGTGCCCAGAGACATTGTGTACN
  
• Restriction Sites: Please inquire
• ACCN: NM_000359
• Insert Size: 2759 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000359.1, NP_000350.1
• RefSeq Size: 2709 bp
• RefSeq ORF: 2454 bp
• Locus ID: 7051
• Cytogenetics: 14q12
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008]'