IL1RA (IL1RN) (NM_000577) Human Untagged Clone

CAT#: SC122567

IL1RN (untagged)-Human interleukin 1 receptor antagonist (IL1RN), transcript variant 3


  "NM_000577" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IL1RN
Synonyms DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000577 edited
GGAAGACCTCCTGTCCTATCAGGCCCTCCCCATGGCTTTAGAGACGATCTGCCGACCCTC
TGGGAGAAAATCCAGCAAGATGCAAGCCTTCAGAATCTGGGATGTTAACCAGAAGACCTT
CTATCTGAGGAACAACCAACTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGA
AGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGG
GAAGATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGT
TAACATCACTGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTC
AGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCAC
AGCGATGGAAGCTGACCAGCCCGTCAGCCTCACCAATATGCCTGACGAAGGCGTCATGGT
CACCAAATTCTACTTCCAGGAGGACGAGTAGTACTGCCCAGGCCTGCCTGTTCCCATTCT
TGCATGGCAAGGACTGCAGGGACTGCCAGTCCCCCTGCCCCAGGGCTCCCGGCTATGGGG
GCACTGAGGACCAGCCATTGAGGGGTGGACCCTCAGAAGGCGTCACAACAACCTGGTCAC
AGGACTCTGCCTCCTCTTCAACTGACCAGCCTCCATGCTGCCTCCAGAATGGTCTTTCTA
ATGTGTGAATCAGAGCACAGCAGCCCCTGCACAAAGCCCTTCCATGTCGCCTCTGCATTC
AGGATCAAACCCCGACCACCTGCCCAACCTGCTCTCCTCTTGCCACTGCCTCTTCCTCCC
TCATTCCACCTTCCCATGCCCTGGATCCATCAGGCCACTTGATGACCCCCAACCAAGTGG
CTCCCACACCCTGTTTTACAAAAAAGAAAAGACCAGTCCATGAGGGAGGTTTTTAAGGGT
TTGTGGAAAATGAAAATTAGGATTTCATGATTTTTTTTTTTCAGTCCCCGTGAAGGAGAG
CCCTTCATTTGGAGATTATGTTCTTTCGGGGAGAGGCTGAGGACTTAAAATATTCCTGCA
TTTGTGAAATGATGGTGAAAGTAAGTGGTAGCTTTTCCCTTCTTTTTCTTCTTTTTTTGT
GATGTCCCAACTTGTAAAAATTAAAAGTTATGGTACTATGTTAGCCCCATAATTTTTTTT
TTCCTTTTAAAACACTTCCATAATCTGGACTCCTCTGTCCAGGCACTGCTGCCCAGCCTC
CAAGCTCCATCTCCACTCCAGATTTTTTACAGCTGCCTGCAGTACTTTACCTCCTATCAG
AAGTTTCTCAGCTCCCAAGGCTCTGAGCAAATGTGGCTCCTGGGGGTTCTTTCTTCCTCT
GCTGAAGGAATAAATTGCTCCTTGACATTGTAGAGCTTCTGGCACTTGGAGACTTGTATG
AAAGATGGCTGTGCCTCTGCCTGTCTCCCCCACCAGGCTGGGAGCTCTGCAGAGCAGGAA
ACATGACTCGTATATGTCTCAGGTCCCTGCAGGGCCAAGCACCTAGCCTCGCTCTTGGCA
GGTACTCAGCGAATGAATGCTGTATATGTTGGGTGCAAAGTTCCCTACTTCCTGTGACTT
CAGCTCTGTTTTACAATAAAATCTTGAAAATGCCTAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_000577 unedited
ATAGCGTTCGCTTTTGTATACGACTCATTTAGGGCGGCCGCGTAATTCGCACGAGGGGGA
ANACCTCCTGTCCTATCAGGCCCTCCCCTGGCTTTAGAGACGATCTGCCGACCCTCTGGG
CAGAAAATCCAGCAAGATGCAAGCCTTCATAATCTGGGATGTTAACCAGAAGACCTTCTA
TCTGAGGAACAACCAACTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGAAGA
AAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGGGAA
GATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGTTAA
CATCACTGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTCAGA
CAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCACAGC
GATGGAAGCTGACCAGCCCGTCAGCCTCACCAATATGCCTGACGAATGCGTCATGGTCAC
CAAATTCTACTTCCAGGAGGACGAGTAGTACTGCCCAGGCCTGCCTGTTCCCATTCTTGC
ATGGCAAGGACTGCAGGGACTGCCAGTCCCCCTGCCCCAGGGCTCCCGGCTATGGGGGCA
CTGAGGACCCGCCATTGAGGGGTGGACCCTCAGAAGGCGTCACAACAACCTGGTCACAGG
ACTCTGCCTCCCCTTCAACTGACCAGCCTCCTTGCTGCCTACAGAATGGTCTTTCTAATG
TGTGAATCACACCCAGCATCCCCTTGAAAAGGCCTTTCCAGGTCGCTTTGGCTTTATGAT
CAAACCCCGGACCACTGGCCAACCGCTTTTCTCTTGGCATTGGCCCTTCCTTCCCTCATC
CGACCTGGCAG
Restriction Sites Please inquire     
ACCN NM_000577
Insert Size 1716 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000577.3, NP_000568.1
RefSeq Size 1802 bp
RefSeq ORF 480 bp
Locus ID 3557
Cytogenetics 2q14.1
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]'
Transcript Variant: This variant (3) lacks an inframe coding segment, as compared to variant 2. The resulting isoform (3) lacks an internal region, as compared to the longest isoform (2).

Other Versions

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