Flavin containing monooxygenase 4 (FMO4) (NM_002022) Human Untagged Clone

CAT#: SC122615

FMO4 (untagged)-Human flavin containing monooxygenase 4 (FMO4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FMO4
• Synonyms: FMO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002022 edited
  AGAAAAGACGAATGGCTTTTGTTTTAAACTGAGGGCACTTTTACAAAAGTCATCTTTCCA
  TTTATTTTTCTTTCAGAAAAAAGAATTTGGGTTTTGAGCTTTTTTAAAAAAAAAAGACAA
  ACACTTTCCTTGACTTTGAGAAATAATTTAAGTCAAAGAATCTGCTCTATGCTAACCAAG
  AGATAGAGCACAGCAAAGATCTGCCAGCCCCAGGCCTCTACCTAGTGGCCTGGAAATTCA
  AGTATTCTTATTGGTGGAGGCCATTTGTTTCTGATTAGAAGCTGTCTAAACCTCCTACTC
  CTCAACTCAAAGGAAAACACAGAGCATACCATGGCCAAGAAAGTTGCAGTGATTGGAGCT
  GGTGTGAGTGGCCTCTCCTCCATCAAATGCTGTGTGGATGAGGACCTGGAGCCCACCTGC
  TTTGAGAGAAGTGATGACATTGGGGGATTATGGAAGTTTACTGAATCTTCCAAAGATGGG
  ATGACCAGGGTCTATAAGTCATTAGTGACAAATGTCTGTAAGGAAATGTCATGTTACAGT
  GACTTCCCTTTCCACGAAGATTATCCTAATTTCATGAACCATGAAAAATTTTGGGACTAT
  CTCCAAGAATTTGCTGAGCACTTTGACCTCCTGAAATACATTCAGTTTAAGACCACTGTG
  TGCAGCATAACGAAGCGTCCAGACTTCTCCGAAACTGGTCAGTGGGATGTTGTCACAGAG
  ACAGAGGGCAAGCAAAATAGAGCTGTCTTTGATGCTGTTATGGTTTGCACTGGACATTTC
  CTGAATCCCCATTTACCTTTGGAAGCCTTTCCTGGAATTCATAAGTTTAAAGGTCAGATC
  CTGCATAGTCAAGAGTACAAGATCCCAGAAGGCTTTCAGGGCAAACGCGTCTTGGTGATT
  GGTCTTGGGAACACTGGAGGAGACATTGCTGTGGAACTCAGTCGAACGGCAGCTCAGGTA
  CTTCTCAGTACTAGAACTGGTACCTGGGTTCTTGGGCGCTCTTCAGATTGGGGCTATCCT
  TATAATATGATGGTTACAAGAAGATGCTGTAGTTTTATTGCACAAGTTCTGCCTTCACGT
  TTTCTAAACTGGATTCAAGAAAGGAAGTTGAATAAGAGATTTAATCATGAGGATTATGGA
  TTAAGTATTACCAAAGGGAAAAAAGCAAAATTCATTGTGAATGATGAGCTGCCAAACTGT
  ATCCTCTGTGGGGCAATCACTATGAAAACCAGCGTGATTGAATTTACAGAAACCTCTGCT
  GTCTTTGAAGATGGGACAGTGGAAGAAAACATTGATGTTGTGATCTTCACTACAGGATAT
  ACATTTTCTTTTCCATTTTTTGAAGAACCTCTTAAAAGCCTCTGTACAAAGAAGATATTT
  CTATACAAGCAAGTCTTTCCCTTAAACCTAGAGAGAGCGACATTAGCCATCATCGGCCTT
  ATCGGCCTTAAAGGATCCATCTTATCAGGCACAGAGCTCCAAGCACGATGGGTCACAAGA
  GTATTCAAAGGACTCTGTAAGATACCTCCATCCCAAAAATTGATGATGGAGGCTACTGAA
  AAGGAACAGCTCATTAAAAGGGGAGTGTTTAAAGACACCAGCAAAGACAAATTTGACTAC
  ATTGCCTACATGGATGATATCGCTGCCTGCATAGGCACAAAGCCCAGCATCCCACTTCTG
  TTCCTCAAGGATCCCAGACTAGCTTGGGAAGTTTTCTTTGGACCATGTACTCCTTATCAG
  TACCGCCTCATGGGCCCTGGAAAATGGGATGGAGCCAGAAATGCCATCCTGACCCAGTGG
  GACAGAACATTGAAACCTTTAAAAACTCGAATTGTCCCTGATTCCTCCAAGCCTGCCTCC
  ATGTCACATTATTTAAAAGCCTGGGGGGCACCTGTCCTACTTGCCTCTCTTCTACTTATC
  TGTAAATCTTCACTTTTCTTGAAATTGGTGAGAGATAAACTACAGGACAGAATGTCCCCT
  TACCTAGTAAGTCTTTGGCGAGGATGAACCTGATTGTTACAAGGGTTACACAAAGTCATG
  CTAATTCTATCTCCAAGTATCTTGTGCATCCCTCCTCTGCTCTCCATCATAACTGCTATT
  AGCCAAATTCAGGCCCAGTCATCTCCTATCTGAATTATTGTATTATCTTCTTCTTTGTTT
  TCAGTACCCTCTTTCTTGCCACCCTTTCCAATGCATCTTCTACCCTGCTACCTCAGTGAT
  TATTCTAAAATAAATATATATGATATGGTTTAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002022 unedited
  NNNGGCGGTTCGCATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGCAGA
  AAAGACGAATGGCTTTTGTTTTAAACTGAGGGCACTTTTACAAAAGTCATCTTTCCATTT
  ATTTTTCTTTCAGAAAAAAGAATTTGGGTTTTGAGCTTTTTTAAAAAAAAAAGACAAACA
  CTTTCCTTGACTTTGAGAAATAATTTAAGTCAAAGAATCTGCTCTATGCTAACCAAGAGA
  TAGAGCACAGCAAAGATCTGCCAGCCCCAGGCCTCTACCTAGTGGCCTGGAAATTCAAGT
  ATTCTTATTGGTGGAGGCCATTTGTTTCTGATTAGAAGCTGTCTAAACCTCCTACTCCTC
  AACTCAAAGGAAAACACAGAGCATACCATGGCCAAGAAAGTTGCAGTGATTGGAGCTGGT
  GTGAGTGGCCTCTCCTCCATCAAATGCTGTGTGGATGAGGACCTGGAGCCCACCTGCTTT
  GAGAGAAGTGATGACATTGGGGGATTATGGAAGTTTACTGAATCTTCCAAAGATGGGATG
  ACCAGGGTCTATAAGTCATTAGTGACAAATGTCTGTAAGGAAATGTCATGTTACAGTGAC
  TTCCCTTTCCACGAAGATTATCCTAATTTCATGAACCATGAAAAATTTTGGGACTATCTC
  CAAGAATTTGCTGAGCACTTTGACCTCCTGAAATACATTCAGTTTAAGACCACTGTGTGC
  AGCATAACGAAGCGTCCAGACTTCTCCGANACTGGTCAGTGGGATGTTGTCACAGAGACA
  GAGGGCAAGCAAAATAGAGCTGTCTTTGATGCTGTTATGGTTTGCACTGGACATTTCCTG
  AATCCNCATTTACCTTTGGAAGCCTTNNCTGGGANNTCATAAGTTAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_002022
• ORF Size: 1677 bp
• Insert Size: 2279
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_002022.1, NP_002013.1
• RefSeq Size: 2148
• RefSeq ORF: 1677
• Locus ID: 2329
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Drug metabolism - cytochrome P450
• Gene Summary: Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jan 2015]