PAX8 (NM_003466) Human Untagged Clone

CAT#: SC122658

PAX8 (untagged)-Human paired box 8 (PAX8), transcript variant PAX8A


  "NM_003466" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PAX8
Synonyms OTTHUMP00000158659; OTTHUMP00000158660; paired box 8; paired domain gene 8
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_003466 edited
CTTCAGAAGGAGGAGAGACACCGGGCCCAGGGCACCCTCGCGGGCGGACCCAAGCAGTGA
GGGCCTGCAGCCGGCCGGCCAGGGCAGCGGCAGGCGCGGCCCGGACCTACGGGAGGAAGC
CCCGAGCCCTCGGCGGGCTGCGAGCGACTCCCCGGCGATGCCTCACAACTCCATCAGATC
TGGCCATGGAGGGCTGAACCAGCTGGGAGGGGCCTTTGTGAATGGCAGACCTCTGCCGGA
AGTGGTCCGCCAGCGCATCGTAGACCTGGCCCACCAGGGTGTAAGGCCCTGCGACATCTC
TCGCCAGCTCCGCGTCAGCCATGGCTGCGTCAGCAAGATCCTTGGCAGGTACTACGAGAC
TGGCAGCATCCGGCCTGGAGTGATAGGGGGCTCCAAGCCCAAGGTGGCCACCCCCAAGGT
GGTGGAGAAGATTGGGGACTACAAACGCCAGAACCCTACCATGTTTGCCTGGGAGATCCG
AGACCGGCTCCTGGCTGAGGGCGTCTGTGACAATGACACTGTGCCCAGTGTCAGCTCCAT
TAATAGAATCATCCGGACCAAAGTGCAGCAACCATTCAACCTCCCTATGGACAGCTGCGT
GGCCACCAAGTCCCTGAGTCCCGGACACACGCTGATCCCCAGCTCAGCTGTAACTCCCCC
GGAGTCACCCCAGTCGGATTCCCTGGGCTCCACCTACTCCATCAATGGGCTCCTGGGCAT
CGCTCAGCCTGGCAGCGACAAGAGGAAAATGGATGACAGTGATCAGGATAGCTGCCGACT
AAGCATTGACTCACAGAGCAGCAGCAGCGGACCCCGAAAGCACCTTCGCACGGATGCCTT
CAGCCAGCACCACCTCGAGCCGCTCGAGTGCCCATTTGAGCGGCAGCACTACCCAGAGGC
CTATGCCTCCCCCAGCCACACCAAAGGCGAGCAGGGCCTCTACCCGCTGCCCTTGCTCAA
CAGCACCCTGGACGACGGGAAGGCCACCCTGACCCCTTCCAACACGCCACTGGGGCGCAA
CCTCTCGACTCACCAGACCTACCCCGTGGTGGCAGATCCTCACTCACCCTTCGCCATAAA
GCAGGAAACCCCCGAGGTGTCCAGTTCTAGCTCCACCCCTTCCTCTTTATCTAGCTCCGC
CTTTTTGGATCTGCAGCAAGTCGGCTCCGGGGTCCCGCCCTTCAATGCCTTTCCCCATGC
TGCCTCCGTGTACGGGCAGTTCACGGGCCAGGCCCTCCTCTCAGGGCGAGAGATGGTGGG
GCCCACGCTGCCCGGATACCCACCCCACATCCCCACCAGCGGACAGGGCAGCTATGCCTC
CTCTGCCATCGCAGGCATGGTGGCAGGAAGTGAATACTCTGGCAATGCCTATGGCCACAC
CCCCTACTCCTCCTACAGCGAGGCCTGGCGCTTCCCCAACTCCAGCTTGCTGAGTTCCCC
ATATTATTACAGTTCCACATCAAGGCCGAGTGCACCGCCCACCACTGCCACGGCCTTTGA
CCATCTGTAGTTGCCATGGGGACAGTGGGAGCGACTGAGCAACAGGAGGACTCAGCCTGG
GACAGGCCCCAGAGAGTCACACAAAGGAATCTTTATTTATTACATGAAAAATAACCACAA
GTCCAGCATTGCGGCACACTCCCTGTGTGGTTAATTTAATGAACCATGAAAGACAGGATG
ACCTTGGACAAGGCCAAACTGTCCTCCAAGACTCCTTAATGAGGGGCAGGAGTCCCAGGG
AAAGAGAACCATGCCATGCTGAAAAAGACAAAATTGAAGAAGAAATGTAGCCCCCAGCCG
GTACCCACCAAAGGAGAGAAGAAGCAATAGCCGAGGAACTTGGGGGGATGGCGAATGGTT
CCTGCCCGGGCCCAAGGGGTGCACAGGGCACCTCCATGGCTCCATTATTAACACAACTCT
AGCAATTATGGACCATAAGCACTTCCCTCCAGCCCACAAGTCACAGCCTGGTGCCGAGGC
TCTCCTCACCAGCCACCCAGGGAGTCACCTCCCTCAGCCTCCCGCCTGCCCCACACGGAG
GCTCTGGCTGTCCTCTTTCTCCACTCCATTTGCTTGGCTCTTTCTACACCTCCCTCTTGG
GCATGGGCTGAGGGCTGGAGCGAGTCCCTCAGAAATTCCACCAGGCTGTCAGCTGACCTC
TTTTGCCTGCTGCTGTGAAGGTATAGCACCACCCCAGGTCCTCCTGCAGTGCGGCATCCC
CTTGGCAGCTGCCGTCAGCCAGGCCAGCCCCAGGGAGCTTAAAACAGACATTCCACAGGG
CCTGGGCCCCTGGGAGGTGAGGTGTGGTGTGCGGCTTCACCCAGGGCAGAACAAGGCAGA
ATCGCAGGAAACCCGCTTCCCCTTCCTGACAGCTCCTGCCAAGCCAAATGTGCTTCCTGC
AGCTCACGCCCACCAGCTACTGAAGGGACCCAAGGCACCCCCTGAAGCCAGCGATAGAGG
GTCCCTCTCTGCTCCCCAGCAGCTCCTGCCCCCAAGGCCTGACTGTATATACTGTCAATG
AAACTTTGTTTGGGTCAAGCTTCCTTCTTTCTACCCCCCAGACTTTGGCCTCTGAGTGAA
ATGTCTCTCTTTGCCCTGTGGGGCTTCTCTCCTTGATGCTTCTTTCTTTTTTTAAAGACA
ACCTGCCATTACCACATGACTCAATAAACCATTGCTCTTCAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_003466 unedited
NNAATAGCCGTACAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAG
GCTTCAGAAGGAGAGAGACACCGGGCCCAGGGCACCCTCGCGGGCGGACCCAAGCAGTGA
GGGCCTGCAGCCGGCCGGCCAGGGCAGCGGCAGGCGCGGCCCGGACCTACGGGAGGAAGC
CCCGAGCCCTCGGCGGGCTGCGAGCGACTCCCCGGCGATGCCTCACAACTCCATCAGATC
TGGCCATGGAGGGCTGAACCAGCTGGGAGGGGCCTTTGTGAATGGCAGACCTCTGCCGGA
AGTGGTCCGCCAGCGCATCGTAGACCTGGCCCACCAGGGTGTAAGGCCCTGCGACATCTC
TCGCCAGCTCCGCGTCAGCCATGGCTGCGTCAGCAAGATCCTTGGCAGGTACTACGAGAC
TGGCAGCATCCGGCCTGGAGTGATAGGGGGCTCCAAGCCCAAGGTGGCCACCCCCAAGGT
GGTGGAGAAGATTGGGGACTACAAACGCCAGAACCCTACCATGTTTGCCTGGGAGATCCG
AGACCGGCTCCTGGCTGAGGGCGTCTGTGACAATGACACTGTGCCCAGTGTCAGATCCAT
TAATAGAATCATCCGGACCAAAGTGCAGCAACCATTCAACCTCCCTATGGACAGCTGCGT
GGCCACCAAGTCCCTGAGTCCCGGACACACGCTGATCCCCAGCTCAGCTGTAACTCCCCC
CGGAGTCACCCCAGTTCGGATTCCCCTGGGCTCCACCTACTTCATCAATGGGCTCCTGGG
CATCGCTCAACCTGGGCAGCGCAAGAGGAAAAGGTTGACAGTGGTCAGGATAACTGCCCA
TAAACATTGGCTTCCAGAACAGCAGCAACGGACCCCGAAA
Restriction Sites Please inquire     
ACCN NM_003466
ORF Size 1353 bp
Insert Size 2698
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_003466.2, NP_003457.1
RefSeq Size 2707
RefSeq ORF 1353
Locus ID 7849
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Thyroid cancer
Gene Summary This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Transcript Variant: This variant (PAX8A) represents the longest transcript and encodes the longest isoform (PAX8A).

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