RASAL1 (NM_004658) Human Untagged Clone

CAT#: SC122686

RASAL1 (untagged)-Human RAS protein activator like 1 (GAP1 like) (RASAL1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASAL1
• Synonyms: RASAL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004658 edited
  CCCCGGGCACCTACACCTTCTCCTCTTTCGGAAATCTCCCATCCAGCTACCCGGGTCTCG
  GACAGGCGGCACTGGGACCACGAGGCAGGGAGCCAGGCTTGAAGCAGGTGACATGTAGAC
  GTCCCCTGGTCCAGCCTCGGAACCTGAGCGCCCTTCTGCCTGGAAAGTTTGTGGCTAGGC
  GCCATGGCCAAGAGCAGCTCCCTGAATGTTCGCGTGGTGGAGGGCCGCGCGCTGCCTGCC
  AAGGACGTGTCTGGGAGCAGCGACCCCTACTGCCTAGTGAAAGTGGACGACGAGGTGGTG
  GCCAGGACAGCTACTGTCTGGAGGAGCCTGGGCCCCTTCTGGGGGGAGGAGTACACGGTG
  CACCTGCCTCTGGATTTCCACCAGCTGGCCTTCTACGTGCTGGATGAGGACACTGTCGGG
  CACGACGACATCATCGGCAAGATCTCGCTGAGCAGGGAGGCGATTACAGCCGACCCCCGA
  GGGATTGACAGCTGGATTAACTTGAGCCGAGTGGACCCAGATGCAGAAGTGCAGGGTGAG
  ATCTGCCTGTCAGTGCAGATGCTGGAGGATGGGCAGGGCCGCTGCCTTCGCTGCCATGTG
  CTTCAGGCCAGGGACCTGGCTCCCAGAGACATCTCTGGCACATCTGACCCATTTGCACGT
  GTGTTTTGGGGCAGCCAGAGCTTGGAGACCTCAACCATCAAGAAGACTCGCTTCCCGCAC
  TGGGATGAAGTGCTGGAGCTGCGGGAGATGCCAGGTGCCCCGTCCCCACTGCGGGTGGAG
  CTCTGGGACTGGGACATGGTGGGCAAGAATGACTTCTTGGGCATGGTGGAGTTCTCTCCA
  AAGACCCTCCAGCAGAAGCCACCTAAAGGCTGGTTCCGCCTCCTGCCCTTTCCCAGAGCC
  GAGGAGGATTCTGGGGGGAACCTGGGTGCCCTGCGAGTGAAGGTACGCCTGATTGAGGAC
  CGCGTCCTGCCCTCCCAGTGCTACCAGCCTCTCATGGAGCTGCTCATGGAGTCTGTGCAG
  GGGCCAGCAGAGGAGGACACTGCTAGCCCCTTGGCTTTGCTGGAAGAGCTGACCTTGGGG
  GACTGCCGCCAGGACCTTGCCACCAAGCTGGTGAAACTCTTTCTTGGCCGGGGACTGGCT
  GGGCACTTTCTGGACTATCTCACCCGGCGTGAGGTGGCTCGGACCATGGACCCCAACACC
  CTCTTCCGTTCTAACTCCCTGGCATCCAAGTCGATGGAACAGTTTATGAAGCTCGTGGGC
  ATGCCCTACCTGCACGAGGTCCTGAAGCCTGTGATTAGCCGTGTCTTTGAGGAGAAGAAG
  TACATGGAGCTGGATCCCTGCAAGATGGACCTGGGCCGCACCCGGAGGATCTCCTTCAAA
  GGCGCACTCTCGGAGGAGCAGATGCGGGAGACCAGCCTGGGGCTGCTGACGGGCTACCTG
  GGGCCCATCGTGGACGCCATCGTGGGCTCCGTGGGGCGCTGCCCGCCCGCCATGCGCCTC
  GCCTTCAAGCAGCTGCACCGGCGAGTGGAGGAGCGCTTCCCCCAGGCCGAGCACCAGGAT
  GTGAAGTACCTGGCCATCAGTGGATTTCTCTTCTTGCGATTCTTCGCACCTGCCATCCTT
  ACCCCAAAGCTGTTTGACCTTCGGGACCAACACGCGGACCCCCAGACTAGCCGCTCACTG
  CTGTTGCTTGCCAAGGCTGTGCAGAGCATTGGAAACCTGGGCCAGCAGCTGGGCCAAGGC
  AAGGAACTGTGGATGGCCCCCCTGCACCCCTTCCTGCTGCAGTGTGTCTCACGTGTGAGA
  GACTTCCTGGACCGGCTGGTGGATGTGGATGGGGATGAAGCTGGTGTCCCAGCCAGGGCC
  CTGTTCCCGCCCTCGGCCATTGTTCGAGAAGGCTATCTGCTGAAGCGCAAGGAGGAGCCT
  GCCGGCCTGGCCACGCGCTTTGCCTTCAAGAAGCGCTACGTCTGGCTCAGCGGGGAGACC
  CTCTCCTTCTCCAAGAGTCCTGAGTGGCAGGTGGTGACGCAGGACGGCACGGGGGCGCTG
  CACACCACCTACCTCCAGTGCAAGAATGTGAATGAGCTCAACCAGTGGCTCTCGGCCTTG
  CGCAAGGCCAGCGCCCCCAACCCGAACAAGCTGGCCGCCTGCCACCCCGGTGCCTTCCGC
  AGCGCGCGCTGGACCTGCTGCCTCCAGGCTGAGCGCTCAGCCGCCGGCTGCAGCCGTACA
  CACTCAGCTGTCACCCTGGGGGACTGGAGTGACCCACTGGATCCTGATGCTGAGGCCCAG
  ACAGTGTATCGGCAGCTGCTCCTGGGGCGGGACCAGCTCAGGCTGAAATTACTGGAGGAT
  TCTAACATGGATACAACTCTGGAGGCAGACACAGGGGCCTGTCCTGAGGTCCTGGCCCGG
  CAAAGAGCAGCAACTGCCCGCCTGCTGGAGGTGCTCGCAGACCTGGATCGTGCCCACGAG
  GAGTTCCAGCAGCAGGAGCGAGGGAAGGCGGCCCTGGGCCCCCTTGGCCCCTAAGGAAAT
  GCCAGAGCTAGCCCGGAAGGAGGAGCAAGAGCCAGGGGGCCCTCTTCAGCGCATCCTGCC
  CCGGGAGTCTCCTGTCTCCTTGGACCTCTTTGATTCTGTGGTTTGGAGGCTCCCAGAGAC
  GTGCCTAGTCCTGTGTGCCTTGAGTCCAGAACTCAGGGCATGGAAGCCCTTTGGCAGGGG
  CCAGCCTTGCACTGAGTGAAACTTGCCCTCTGGCTTGATTCAGACTGGAGTGGATAGGAT
  AAGGAACCTGACTTATTTGACTGAGACTGGGGTCTCTACTTCACCAAACTGGCCTCTATC
  CATACCAAGGAGGCCAGCCTGGCCCTGAGCTGCTGGATACAGCTGGACCTGAATTCCTGA
  TGCCCATGTGATGTTGTTGCCCCAGATGGGCACTAAATGGCCTCACTCCTTCCTGAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004658 unedited
  GAAACGTCAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCCC
  GGGCACCTACACCTTCTCCTCTTTCGGAAATCTCCCATCCAGCTACCCGGGTCTCGGACA
  GGCGGCACTGGGACCACGAGGCAGGGAGCCAGGCTTGAAGCAGGTGACATGTAGACGTCC
  CCTGGTCCAGCCTCGGAACCTGAGCGCCCTTCTGCCTGGAAAGTTTGTGGCTAGGCGCCA
  TGGCCAAGAGCAGCTCCCTGAATGTTCGCGTGGTGGAGGGCCGCGCGCTGCCTGCCAAGG
  ACGTGTCTGGGAGCAGCGACCCCTACTGCCTAGTGAAAGTGGACGACGAGGTGGTGGCCA
  GGACAGCTACTGTCTGGAGGAGCCTGGGCCCCTTCTGGGGGGAGGAGTACACGGTGCACC
  TGCCTCTGGATTTCCACCAGCTGGCCTTCTACGTGCTGGATGAGGACACTGTCGGGCACG
  ACGACATCATCGGCAAGATCTCGCTGAGCAGGGAGGCGATTACAGCCGACCCCCGAGGGA
  TTGACAGCTGGATTAACTTGAGCCGAGTGGACCCAGATGCAGAAGTGCAGGGTGAGATCT
  GCCTGTCAGTGCAGATGCTGGAGGATGGGCAGGGCCGCTGCCTTCGCTGCCATGTGCTTC
  AGGCCAGGGACCTGGCTCCCAGAGACATCTCTGGCACATCTGACCCATTTGCACGTGTGT
  TTTGGGGCAGCCAGAGCTTGGAGACCTCAACCATCAAGAAGACTCGCTTCCCGCACTGGG
  ATGAAGTGCTGGAGCTGCNGGAGATGCCCAGTGCCCCGTCCCCCTGCGGGTGGAGCTCTG
  GGACTGGGACATGGTGGGCAAGAATGACTTCTTGGGCATGGTGGAGTTCTCTCCAAACCC
  TA
  
• Restriction Sites: Please inquire
• ACCN: NM_004658
• ORF Size: 2415 bp
• Insert Size: 3028
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004658.1, NP_004649.1
• RefSeq Size: 3148
• RefSeq ORF: 2415
• Locus ID: 8437
• Gene Summary: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR and uses two alternate, in-frame splice sites in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.