ALS (IGFALS) (NM_004970) Human Untagged Clone

CAT#: SC122694

IGFALS (untagged)-Human insulin-like growth factor binding protein, acid labile subunit (IGFALS), transcript variant 2


  "NM_004970" in other vectors (4)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IGFALS
Synonyms ACLSD; ALS
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_004970 edited
GGAAATCCAGAGGGCAGGGGTGGCCGGCACAGCAGACGTACCCTCCCTCGCTGCCTGCCT
GCAGCCTGCCCTGCATGCAGGATGGCCCTGAGGAAAGGAGGCCTGGCCCTGGCGCTGCTG
CTGCTGTCCTGGGTGGCACTGGGCCCCCGCAGCCTGGAGGGAGCAGACCCCGGAACGCCG
GGGGAAGCCGAGGGCCCAGCGTGCCCGGCCGCCTGTGTCTGCAGCTACGATGACGACGCG
GATGAGCTCAGCGTCTTCTGCAGCTCCAGGAACCTCACGCGCCTGCCTGATGGAGTCCCG
GGCGGCACCCAAGCCCTGTGGCTGGACGGCAACAACCTCTCGTCCGTCCCCCCGGCAGCC
TTCCAGAACCTCTCCAGCCTGGGCTTCCTCAACCTGCAGGGCGGCCAGCTGGGCAGCCTG
GAGCCACAGGCGCTGCTGGGCCTAGAGAACCTGTGCCACCTGCACCTGGAGCGGAACCAG
CTGCGCAGCCTGGCACTCGGCACGTTTGCACACACGCCCGCGCTGGCCTCGCTCGGCCTC
AGCAACAACCGTCTGAGCAGGCTGGAGGACGGGCTCTTCGAGGGCCTCGGCAGCCTCTGG
GACCTCAACCTCGGCTGGAATAGCCTGGCGGTGCTCCCCGATGCGGCGTTCCGCGGCCTG
GGCAGCCTGCGCGAGCTGGTGCTGGCGGGCAACAGGCTGGCCTACCTGCAGCCCGCGCTC
TTCAGCGGCCTGGCCGAGCTCCGGGAGCTGGACCTGAGCAGGAACGCGCTGCGGGCCATC
AAGGCAAACGTGTTCGTGCAGCTGCCCCGGCTCCAGAAACTCTACCTGGACCGCAACCTC
ATCGCTGCCGTGGCCCCGGGCGCCTTCCTGGGCCTGAAGGCGCTGCGATGGCTGGACCTG
TCCCACAACCGCGTGGCTGGCCTCCTGGAGGACACGTTCCCCGGTCTGCTGGGCCTGCGT
GTGCTGCGGCTGTCCCACAACGCCATCGCCAGCCTGCGGCCCCGCACCTTCAAGGACCTG
CACTTCCTGGAGGAGCTGCAGCTGGGCCACAACCGCATCCGGCAGCTGGCTGAGCGCAGC
TTTGAGGGCCTGGGGCAGCTTGAGGTGCTCACGCTAGACCACAACCAGCTCCAGGAGGTC
AAGGCGGGCGCTTTCCTCGGCCTCACCAACATGGCGGTCATGAACCTCTCTGGGAACTGT
CTCCGGAACCTTCCGGAGCAGGTGTTCCGGGGCCTGGGCAAGCTGCACAGCCTGCACCTG
GAGGGCAGCTGCCTGGGACGCATCCGCCCGCACACCTTCACCGGCCTCTCGGGGCTCCGC
CGACTCTTCCTCAAGGACAACGGCCTCGTGGGCATTGAGGAGCAGAGCCTGTGGGGGCTG
GCGGAGCTGCTGGAGCTCGACCTGACCTCCAACCAGCTCACGCACCTGCCCCACCGCCTC
TTCCAGGGCCTGGGCAAGCTGGAGTACCTGCTGCTCTCCCGCAACCGCCTGGCAGAGCTG
CCGGCGGACGCCCTGGGCCCCCTGCAGCGGGCCTTCTGGCTGGACGTCTCGCACAACCGC
CTGGAGGCATTGCCCAACAGCCTCTTGGCACCACTGGGGCGGCTGCGCTACCTCAGCCTC
AGGAACAACTCACTGCGGACCTTCACGCCGCAGCCCCCGGGCCTGGAGCGCCTGTGGCTG
GAGGGTAACCCCTGGGACTGTGGCTGCCCTCTCAAGGCGCTGCGGGACTTCGCCCTGCAG
AACCCCAGTGCTGTGCCCCGCTTCGTCCAGGCCATCTGTGAGGGGGACGATTGCCAGCCG
CCCGCGTACACCTACAACAACATCACCTGTGCCAGCCCGCCCGAGGTCGTGGGGCTCGAC
CTGCGGGACCTCAGCGAGGCCCACTTTGCTCCCTGCTGACCAGGTCCCCGGACTCAAGCC
CCGGACTCAGGCCCCCACCTGGCTCACCTTGTGCTGGGGACAGGTCCTCAGTGTCCTCAG
GGGCCTGCCCAGTGCACTTGCTGGAAGACGCAAGGGCCTGATGGGGTGGAAGGCATGGCG
GCCCCCCCAGCTGTCATCAATTAAAGGCAAAGGCAATCGAATCTAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA
>OriGene 5' read for NM_004970 unedited
GCGNAATTCCCGGGTATGGAAATCCAGAGTGCAGGGGTGGCCGGCACAGCAGACGTACCC
TCCCTCGCTGCCTGCCTGCAGCCTGCCCTGCATGCAGGATGGCCCTGAGGAAAGGAGGCC
TGGCCCTGGCGCTGCTGCTGCTGTCCTGGGTGGCACTGGGCCCCCGCAGCCTGGAGGGAG
CAGACCCCGGAACGCCGGGGGAAGCCGAGGGCCCAGCGTGCCCGGCCTCCTGTGTCTGCA
GCTACGATGACGACGCGGATGAGCTCAGCGTCTTCTGCAGCTCCAGGAACCTCACGCGCC
TGCCTGATGGAGTCCCGGGCGGCACCCAAGCCCTGTGGCTGGACGGCAACAACCTCTCGT
CCGTCCCCCCGGCAGCCTTCCAGAACCTCTCCAGCCTGGGCTTCCTCAACCTGCAGGGCG
GCCAGCTGGGCAGCCTGGAGCCACAGGCGCTGCTGGGCCTAGAGAACCTGTGCCACCTGC
ACCTGGAGCGGAACCAGCTGCGCAGCCTGGCACTCGGCACGTTTGCACACACGCCCGCGC
TGGCCTCGCTCGGCCTCAGCAACAACCGTCTGAGCAGGCTGGAGGACGGGCTCTTCGAGG
GCCTCGGCAGCCTCTGGGACCTCAACCTCGGCTGGAATAGCCTGGCGGTGCTCCCCGATG
CGGCGTTCCGCGGCCTGGGCAGCCTGCGCGAGCTGGTGCTGGCGGGCAACAGGCTGGCCT
ACCTGCAGCCCGCGCTCTTCAGCGGCCTGGCCGAGCTCCGGGAGCTGGACCTGAGCCAGA
ACGCGCTGCGGGCCATCAAGGCAAACGTGTTCGTGCAGCTGCCCCGGCTCCAGAAACTCT
ACCTGGACCGCAACCTCATCGCTGCCGTGGGCCCCGG
Restriction Sites Please inquire     
ACCN NM_004970
Insert Size 2168 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004970.1, NP_004961.1
RefSeq Size 2125 bp
RefSeq ORF 1818 bp
Locus ID 3483
Cytogenetics 16p13.3
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]'
Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

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