KDELR3 (NM_006855) Human Untagged Clone

CAT#: SC122762

KDELR3 (untagged)-Human KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (KDELR3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDELR3
• Synonyms: ERD2L3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006855 edited
  GGCGCGCGGGTGCGATCGCGGAGCTGTGAGGCGCAGGCAGGGCTCTGGGGCACCTAGAGA
  CCGGGGCCGGAGACGTGGCAGCCGCCCTGCCCGCCAGAAAGTTTCCTAGAAGTTTGCTGG
  GCGCGGGCGCACGACTGACTGGCTGGACCATGAACGTGTTCCGAATCCTCGGCGACCTGA
  GCCACCTCCTGGCCATGATCTTGCTGCTGGGGAAGATCTGGAGGTCCAAGTGCTGCAAGG
  GCATCTCTGGGAAGAGCCAGATCCTGTTTGCTCTCGTCTTCACCACCAGGTACCTGGACC
  TGTTCACCAACTTCATCTCCATCTACAACACAGTAATGAAGGTGGTTTTTCTCCTCTGTG
  CCTATGTTACAGTGTACATGATATATGGGAAATTCCGTAAAACTTTTGACAGTGAGAATG
  ACACATTCCGCCTGGAGTTTCTTCTGGTCCCAGTCATTGGCCTTTCCTTCCTTGAAAACT
  ACAGTTTCACTCTGCTGGAGATCCTCTGGACTTTCTCTATCTATCTGGAATCAGTGGCTA
  TCCTGCCCCAGCTCTTCATGATCAGCAAGACTGGAGAGGCTGAGACCATAACTACTCACT
  ACCTGTTCTTTCTGGGTCTGTACCGGGCACTCTACCTGGCTAACTGGATCAGGCGGTACC
  AGACTGAGAATTTCTATGACCAAATTGCAGTCGTGTCTGGAGTAGTACAAACCATCTTCT
  ACTGTGACTTCTTCTACTTGTATGTGACCAAAGTCCTTAAGGGAAAGAAGTTAAGTCTTC
  CAATGCCAATCTGAGGACCTTCAGAGACAGTCTACGCCTTAACAAGCACATGAAGGAAAC
  TATTTTGAATGTTCTCTTTGGCAACTTATCCATAATTTGGGATCAAATGTTAAAACCAGA
  AAAGTGTTTAGTGTGGATTTCAGCAAAACCTGATCATCCCACCCAGAAGACCTTCTCATC
  AATAGATCGCCCTTAAAGACCCATTGTAAGGTCATAAAAAACCTCGGCCAACTGCACAAA
  GATGGTGCCTCACTGCAACAAGAAACCTTAAGGTGTCTTACCGACGAAATAAAAAACATA
  AATGATTGTTCTCCAAGGCCTGAGGGCAAGACTCATGATGAGCAAGTCAACCCCAATCTG
  GAACAATGTCCCTCCTCTTAGAATGTCCCAACTAAAGACCAGTTAAAATATTAGGGTACG
  TTCTTGTGAATTTCCACTTTCCAGGTAGATGACCAAATTTAGGTGGTCAAGATATAAAGG
  TGACAGCTAGTTTTAAGTGTGAAACTTATTTCACTTTCACACTGCCTTCAGGCCAGAAGC
  AAACCAAATTTACCAGGTTTGGCTGGAGGAGTTTTGTGACTCATCTTTTACTGGTTTGAA
  TTTTTTCAAACCAGTGGCTGATACCTGCCTTGTACTTAGTACCTTAATACCAATAACCTA
  ATGGTACTTAGGCGAGTACCATTTGCACAATCACTGTTTTACTTATGAGCAGATACAGAT
  ATATCCAAACCCTTACCTACTAGGTATCCTGCTAGGGTTTTCAATTCCAATTCTTGTATT
  AAGTTTTTTCCTTTCAGTTTTAGGTGCGAAAGTAATCAGTCAATCCAATATCCCCCATCT
  TTGTCTTGAAACAAAAACTGTTTTAAGACGTCTACGTTGAATTATTCAGAGAATTAAGCA
  ATAAAAGCTCACACCTTATTGTCAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006855 unedited
  NAAGGTCANAATTTGTAATACGACTCACTATAGGGACCGGCCGCGATTCCCGGGATATCG
  TCGACCCACGCGTCCGGGCGCGCGGGTGCGATCGCGGAGCTGTGAGGCGCAGGCAGGGCT
  CTGGGGCACCTAGAGACCGGGGCCGGAGACGTGGCAGCCGCCCTGCCCGCCAGAAAGTTT
  CCTAGAAGTTTGCTGGGCGCGGGCGCACGACTGACTGGCTGGACCATGAACGTGTTCCGA
  ATCCTCGGCGACCTGAGCCACCTCCTGGCCATGATCTTGCTGCTGGGGAAGATCTGGAGG
  TCCAAGTGCTGCAAGGGCATCTCTGGGAAGAGCCAGATCCTGTTTGCTCTCGTCTTCACC
  ACCAGGTACCTGGACCTGTTCACCAACTTCATCTCCATCTACAACACAGTAATGAAGGTG
  GTTTTTCTCCTCTGTGCCTATGTTACAGTGTACATGATATATGGGAAATTCCGTAAAACT
  TTTGACAGTGAGAATGACACATTCCGCCTGGAGTTTCTTCTGGTCCCAGTCATTGGCCTT
  TCCTTCCTTGAAAACTACAGTTTCACTCTGCTGGAGATCCTCTGGACTTTCTCTATCTAT
  CTGGAATCAGTGGCTATCCTGCCCCAGCTCTTCATGATCAGCAAGACTGGAGAGGCTGAG
  ACCATAACTACTCACTACCTGTTCTTTCTGGGTCTGTACCGGGCACTCTACCTGGCTAAC
  TGGATCANGCNGTACCAGACTGAGAATTTCTATGACCAAATTGCAGTCGTGTCTGGAGTA
  GTACAAACCATCTTCTACTGTGACTTCTTCTACTTGTATGTGACCAAAGTCCTTAAAGGG
  AAAGAAGTTAAGTCTTTCAATGGCCATCTGAGGACCTTCAGAGACAGTCTACGCCTTAAC
  A
  
• Restriction Sites: Please inquire
• ACCN: NM_006855
• ORF Size: 645 bp
• Insert Size: 1723
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006855.2, NP_006846.1
• RefSeq Size: 1705
• RefSeq ORF: 645
• Locus ID: 11015
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Vibrio cholerae infection
• Gene Summary: This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.