Cbl c (CBLC) (NM_012116) Human Untagged Clone

CAT#: SC122781

CBLC (untagged)-Human Cas-Br-M (murine) ecotropic retroviral transforming sequence c (CBLC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBLC
• Synonyms: CBL-3; CBL-SL; RNF57
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012116 edited
  CCCGGCACACGCGAGGCTCCCATGGCTCTGGCGGTGGCCCCGTGGGGGCGACAGTGGGAA
  GAGGCCCGCGCCCTGGGCCGGGCAGTCAGGATGCTGCAGCGCCTAGAAGAGCAATGCGTC
  GACCCCCGGCTGTCCGTGAGTCCCCCTTCGCTGCGGGACCTGCTGCCCCGCACAGCGCAG
  CTGCTTCGAGAGGTGGCCCATTCTCGGCGGGCGGCCGGCGGAGGCGGCCCCGGGGGTCCC
  GGCGGCTCTGGGGACTTTCTACTCATCTACCTGGCCAATCTGGAGGCCAAGAGCAGGCAG
  GTGGCCGCGCTGCTGCCTCCCCGGGGCCGAAGGAGTGCCAACGACGAGCTCTTCCGGGCG
  GGCTCCAGACTCAGGCGACAGCTGGCCAAGCTGGCCATCATCTTCAGCCACATGCACGCA
  GAGCTGCACGCACTCTTCCCCGGGGGAAAGTACTGTGGACACATGTACCAGCTCACCAAG
  GCCCCCGCCCACACCTTCTGGAGGGAAAGTTGCGGAGCCCGGTGTGTGCTGCCCTGGGCT
  GAGTTTGAGTCCCTCCTGGGCACCTGCCACCCTGTGGAACCAGGCTGCACAGCCCTGGCC
  TTGCGCACCACCATTGACCTCACCTGCAGCGGGCACGTGTCCATCTTCGAGTTCGACGTC
  TTCACCAGGCTCTTTCAGCCATGGCCAACACTCCTCAAGAACTGGCAGCTCCTGGCAGTC
  AACCACCCAGGCTACATGGCCTTCCTCACCTATGATGAGGTCCAAGAGCGTCTGCAGGCC
  TGCAGGGACAAGCCAGGCAGTTACATCTTCCGGCCCAGCTGTACTCGCCTGGGGCAGTGG
  GCCATCGGCTATGTGAGCTCAGATGGCAGCATCCTGCAGACCATCCCTGCCAACAAACCC
  CTGTCCCAGGTGCTCCTGGAGGGACAGAAGGACGGCTTCTACCTCTACCCAGATGGAAAG
  ACCCACAACCCAGACCTGACTGAGCTCGGCCAGGCAGAACCCCAGCAGCGCATCCACGTG
  TCAGAGGAGCAGCTGCAGCTCTACTGGGCCATGGACTCCACATTTGAGCTCTGCAAGATC
  TGTGCTGAGAGCAACAAGGATGTGAAGATTGAGCCGTGCGGGCACCTGCTCTGCAGCTGC
  TGCCTGGCTGCCTGGCAGCACTCGGACAGCCAGACCTGCCCCTTCTGCCGCTGCGAGATC
  AAGGGCTGGGAGGCCGTGAGTATCTACCAGTTCCACGGTCAGGCTACTGCTGAGGACCCA
  GGGAACAGCAGTGACCAGGAAGGCAGGGAGTTGGAGCTGGGGCAGGTGCCCCTTTCGGCT
  CCTCCATTGCCCCCACGGCCAGATCTGCCCCCCAGGAAGCCCAGAAATGCCCAGCCGAAA
  GTGAGACTCCTAAAGGGGAACTCCCCTCCAGCTGCGCTGGGACCCCAGGACCCTGCCCCG
  GCCTGAAGGCCAGGGCACCCAGATGTGCTGCTCAAGGGAGCCCCAAGGGCTGGAAGGGGG
  TTGTGAAACCGAAATAAACTGCCAAGCCTGGTCTGTCAAAAAAAAAAAAAAAAAAAAAAA
  AAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012116 unedited
  GTTTTGATTTGTAAACGACTTATATAGGGCGGCCGCGATTCCCGGGATCCCGGCACACGC
  GAGGCTCCCATGGCTCTGGCGGTGGCCCCGTGGGGGCGACAGTGGGAAGAGGCCCGCGCC
  CTGGGCCGGGCAGTCAGGATGCTGCAGCGCCTAGAAGAGCAATGCGTCGACCCCCGGCTG
  TCCGTGAGTCCCCCTTCGCTGCGGGACCTGCTGCCCCGCACAGCGCAGCTGCTTCGAGAG
  GTGGCCCATTCTCGGCGGGCGGCCGGCGGAGGCGGCCCCGGGGGTCCCGGCGGCTCTGGG
  GACTTTCTACTCATCTACCTGGCCAATCTGGAGGCCAAGAGCAGGCAGGTGGCCGCGCTG
  CTGCCTCCCCGGGGCCGAAGGAGTGCCAACGACGAGCTCTTCCGGGCGGGCTCCAGACTC
  AGGCGACAGCTGGCCAAGCTGGCCATCATCTTCAGCCACATGCACGCAGAGCTGCACGCA
  CTCTTCCCCGGGGGAAAGTACTGTGGACACATGTACCAGCTCACCAAGGCCCCCGCCCAC
  ACCTTCTGGAGGGAAAGTTGCGGAGCCCGGTGTGTGCTGCCCTGGGCTGAGTTTGAGTCC
  CTCCTGGGCACCTGCCACCCTGTGGAACCAGGCTGCACAGCCCTGGCCTTGCGCACCACC
  ATTGACCTCACCTGCAGCGGGCACGTGTCCATCTACGAGTGCGACGTCTTCACCAGGCTC
  TTTCAGCCATGGCCAACACTCCTCAAGGAACTGGGCAGCTCTGGCAGTCAACCACCCAGG
  CTACATGGCCTTCCTCACCTATGATGAGGTCCAAGAGCGTCTGCAGGCCTGCAGGGACNA
  GCCCAGCAGTTACATCTTCCGGCCCAGCTGTACTCGCCTGGGGCAGTGGGCCATNCGCTA
  TGTGAGCTCAGATGGCAGCATCCTGCAGACC
  
• Restriction Sites: Please inquire
• ACCN: NM_012116
• ORF Size: 1425 bp
• Insert Size: 1564
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012116.2, NP_036248.2
• RefSeq Size: 1575
• RefSeq ORF: 1425
• Locus ID: 23624
• Protein Families: Druggable Genome
• Protein Pathways: Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes protein isoform 1.