HSD17B8 (NM_014234) Human Untagged Clone

CAT#: SC122798

HSD17B8 (untagged)-Human hydroxysteroid (17-beta) dehydrogenase 8 (HSD17B8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HSD17B8
• Synonyms: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014234 edited
  GGGATTCCCACCCACCCACAGCCCGCCATGGCGTCTCAGCTCCAGAACCGACTCCGCTCC
  GCACTGGCCTTGGTCACAGGTGCGGGGAGCGGCATCGGCCGAGCGGTCAGTGTACGCCTG
  GCCGGAGAGGGGGCCACCGTAGCTGCCTGCGACCTGGACCGGGCAGCGGCACAGGAGACG
  GTGCGGCTGCTGGGCGGGCCAGGGAGCAAGGAGGGGCCGCCCCGAGGGAACCATGCTGCC
  TTCCAGGCTGACGTGTCTGAGGCCAGGGCCGCCAGGTGCCTGCTGGAACAAGTGCAGGCC
  TGCTTTTCTCGCCCACCATCTGTCGTTGTGTCCTGTGCGGGCATCACCCAGGATGAGTTT
  CTGCTGCACATGTCTGAGGATGACTGGGACAAAGTCATAGCTGTCAACCTCAAGGGCACC
  TTCCTAGTCACTCAGGCTGCAGCACAAGCCCTGGTGTCCAATGGTTGTCGTGGTTCCATC
  ATCAACATCAGTAGCATCGTAGGAAAGGTGGGGAACGTGGGGCAGACAAACTATGCAGCA
  TCCAAGGCTGGAGTGATTGGGCTGACCCAGACCGCAGCCCGGGAGCTTGGACGACATGGG
  ATCCGCTGTAACTCTGTCCTCCCAGGGTTCATTGCAACACCCATGACACAGAAAGTGCCA
  CAGAAAGTGGTGGACAAGATTACTGAAATGATCCCGATGGGACACTTGGGGGACCCTGAG
  GATGTGGCAGATGTGGTCGCATTCTTGGCATCTGAAGATAGTGGATACATCACAGGGACC
  TCAGTGGAAGTCACTGGAGGTCTTTTCATGTAACTGCCTCAAGGACCCTGGACTCTGCTC
  ACCCCCCCACCACTCTGCCTGGCCTCCTGCTGATGAGGACTCTAAGTTCCCAGGATACAA
  AAGGGGTGGCAGTGTATGGTTCAGGAATGCTGAATATGGGAAGCAGGGGTGCTTGTGACC
  CTAATAAATTCCAAGTCCTCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014234 unedited
  GTCAGCATTTGTAATACGACTCACTATAGGGCGGCACGCGATTCCCGGGATATCGTCGAC
  CCACGTCGTCCGGGGATTCCCACCCACCCACAGCCCGCCATGGCGTCTCAGCTCCAGAAC
  CGACTCCGCTCCGCACTGGCCTTGGTCACAGGTGCGGGGAGCGGCATCGGCCGAGCGGTC
  AGTGTACGCCTGGCCGGAGAGGGGGCCACCGTAGCTGCCTGCGACCTGGACCGGGCAGCG
  GCACAGGAGACGGTGCGGCTGCTGGGCGGGCCATGGAGCAAGGAGGGGCCGCCCCGAGGG
  AACCATGCTGCCTTCCAGGCTGACGTGTCTGAGGCCAGGGCCGCCAGGTGCCTGCTGGAA
  CAAGTGCAAGCCTGCTTTTCTCGCCCACCATCTGTCGTTGTGTCCTGTGCGGGCATCACC
  CAGGATGAGTTTCTGCTGCACATGTCTGANGATGACTGGGACAAAGTCATAGCTGTCAAC
  CTCAAGGGCACCTTCCTAGTCACTCAAGCTGCAGCACAAGCCCTGGTGTCCAATGGTTGT
  CGTGGTTCCATCATCAACATCAGTAGCATCGTAGGANAGGTGGGGAACGTGGGGCAGACA
  NACTATGCAGCATCCAAGGCTGGAGTGATTGGGCTGACCCANACCGCAGCCCGGGAGCTT
  GGACGACATGGGATCCGCTGTAACTCTGTCCTCCCAGGGTTCATTGCAACACCCATGACA
  CAGAAAGTGCCACAGAAAGTGGTGGACAAGATTACTGAAATGATCCCGATGGGACACTTG
  GGGGACCCCTGAGATGTGGCANATGTGGTCGCATTCTTGGCATCTGAAGATAGTGGATAC
  ATCACAGGGACCTCANTGGGAGTCACTGGNAGTCCTTTCATGTNACTGCCTCAAGGACCC
  TGGACTCTGCTTACCCCCCACACTCTGCCTGGCTCCTGCTGATAC
  
• Restriction Sites: Please inquire
• ACCN: NM_014234
• ORF Size: 786 bp
• Insert Size: 1039
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014234.3, NP_055049.1
• RefSeq Size: 989
• RefSeq ORF: 786
• Locus ID: 7923
• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, Metabolic pathways
• Gene Summary: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]