DHH (NM_021044) Human Untagged Clone

CAT#: SC122903

DHH (untagged)-Human desert hedgehog (DHH)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DHH
• Synonyms: GDXYM; HHG-3; SRXY7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021044 edited
  GTCCGGAGTCCGGGCGTTCTGGCAGCACCAGAGTCCTGCAGCAGAGACGGGCTGGGCTGG
  CACTCACCCACGACCCCCCTTCCCTGCTATGATGGTTTGTCAGTAGCAGGTCCTAGACAC
  CCCCCGCCCGCTCCCGGGGCACGTGGGCAGAGCTAGCAGCAGCCAGGTGCACGGAGCCAC
  AAGAGCTCTAGGGCACTCTGGGGGCAGCTGTGCCTGCTGCCCTCTCTGGTGCCTGTGGAG
  ATGCCTAACTGACAGGAGAGTTAGTGAGGACAAGAACGCTCCCTTTTGGCCGAGGTCCGC
  TGTATCCATGGCTCTCCTGACCAATCTACTGCCCCTGTGCTGCTTGGCACTTCTGGCGCT
  GCCAGCCCAGAGCTGCGGGCCGGGCCGGGGGCCGGTTGGCCGGCGCCGCTATGCGCGCAA
  GCAGCTCGTGCCGCTACTCTACAAGCAATTTGTGCCCGGCGTGCCAGAGCGGACCCTGGG
  CGCCAGTGGGCCAGCGGAGGGGAGGGTGGCAAGGGGCTCCGAGCGCTTCCGGGACCTCGT
  GCCCAACTACAACCCCGACATCATCTTCAAGGATGAGGAGAACAGTGGAGCCGACCGCCT
  GATGACCGAGCGTTGTAAGGAGCGGGTGAACGCTTTGGCCATTGCCGTGATGAACATGTG
  GCCCGGAGTGCGCCTACGAGTGACTGAGGGCTGGGACGAGGACGGCCACCACGCTCAGGA
  TTCACTCCACTACGAAGGCCGTGCTTTGGACATCACTACGTCTGACCGCGACCGCAACAA
  GTATGGGTTGCTGGCGCGCCTCGCAGTGGAAGCCGGCTTCGACTGGGTCTACTACGAGTC
  CCGCAACCACGTCCACGTGTCGGTCAAAGCTGATAACTCACTGGCGGTCCGGGCGGGCGG
  CTGCTTTCCGGGAAATGCAACTGTGCGCCTGTGGAGCGGCGAGCGGAAAGGGCTGCGGGA
  ACTGCACCGCGGAGACTGGGTTTTGGCGGCCGATGCGTCAGGCCGGGTGGTGCCCACGCC
  GGTGCTGCTCTTCCTGGACCGGGACTTGCAGCGCCGGGCTTCATTTGTGGCTGTGGAGAC
  CGAGTGGCCTCCACGCAAACTGTTGCTCACGCCCTGGCACCTGGTGTTTGCCGCTCGAGG
  GCCGGCGCCCGCGCCAGGCGACTTTGCACCGGTGTTCGCGCGCCGGCTACGCGCTGGGGA
  CTCGGTGCTGGCGCCCGGCGGGGATGCGCTTCGGCCAGCGCGCGTGGCCCGTGTGGCGCG
  GGAGGAAGCCGTGGGCGTGTTCGCGCCGCTCACCGCGCACGGGACGCTGCTGGTGAACGA
  TGTCCTGGCCTCTTGCTACGCGGTTCTGGAGAGTCACCAGTGGGCGCACCGCGCTTTTGC
  CCCCTTGAGACTGCTGCACGCGCTAGGGGCGCTGCTCCCCGGCGGGGCCGTCCAGCCGAC
  TGGCATGCATTGGTACTCTCGGCTCCTCTACCGCTTAGCGGAGGAGCTACTGGGCTGAGC
  GTCCCAGGCATAGAAACCTCGAAGCGCCCGAGGAAACGAGGGCCTGCTGGCTGAGATATG
  GGGCTGTGGGCAGCAGACGATGCCGACTGGAAGGGAGGGAGAGGGAGGGGGAGGGAGAAA
  ATGGGGCTATGCCTGGCTTAGGGGCAACCTCGTACTGAGAGGAGGTGATACCGGGTCCTA
  GGTAGGTAGGGCTGATGGTGCGCACTCCTTAAAGAGGACTATTTAGCCTCTCCCCCAGTG
  CTTCAGCCCCACCCGATAATTTTATTTTATTTCTTATTTATAAATTGTAATATAATGATT
  CCCTTGCCCAGCTTGCCAAGGTGAGGGGCTGGGGCATGGCATTAACACTGTCTGACACAG
  CCAGCCAGTCTGACATCTGACGTTTTCCTGCAAGGTGGGCTAATAAAGGGAAGGCTTTCA
  GGAGCTTACTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021044 unedited
  GTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATCCCGGGNTGTCCGGAGTCCGG
  GCGTTCTGGCAGCACCAGAGTCCTGCAGCAGAGACGGGCTGGGCTGGCACTCACCCACGA
  CCCCCCTTCCCTGCTATGATGGTTTGTCAGTAGCAGGTCCTAGACACCCCCCGCCCGCTC
  CCGGGGCACGTGGGCAGAGCTAGCAGCAGCCAGGTGCACGGAGCCACAAGAGCTCTAGGG
  CACTCTGGGGGCAGCTGTGCCTGCTGCCCTCTCTGGTGCCTGTGGAGATGCCTAACTGAC
  AGGAGAGTTAGTGAGGACAAGAACGCTCCCTTTTGGCCGAGGTCCGCTGTATCCATGGCT
  CTCCTGACCAATCTACTGCCCCTGTGCTGCTTGGCACTTCTGGCGCTGCCAGCCCAGAGC
  TGCGGGCCGGGCCGGGGGCCGGTTGGCCGGCGCCGCTATGCGCGCAAGCAGCTCGTGCCG
  CTACTCTACAAGCAATTTGTGCCCGGCGTGCCAGAGCGGACCCTGGGCGCCAGTGGGCCA
  GCGGAGGGGAGGGTGGCAAGGGGCTCCGAGCGCTTCCGGGACCTCGTGCCCAACTACAAC
  CCCGACATCATCTTCAAGGATGAGGAGAACAGTGGAGCCGACCGCCTGATGACCGAGCGT
  TGTAAGGAGCGGGTGAACGCTTTGGCCATTGCCGTGATGAACATGTGGCCCGGAGTGCGC
  CTACNAGTGACTGAGGGCTGGGACGAGGACGGCCACACGCTCAGGATCACTCACTACGAA
  GCCGTGCCTTGGANTCACTACTTCTGACCGCGACGCAACAGTATGGGTTGCTGGCGCGCC
  TCCAATGAAAGCCGCTTCCACTGGGTTACTACAAGTCCGAACCACGTCCAGTGTCGGTCA
  AGCTGAAACTCACTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_021044
• ORF Size: 1191 bp
• Insert Size: 1971
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021044.2, NP_066382.1
• RefSeq Size: 1971
• RefSeq ORF: 1191
• Locus ID: 50846
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease
• Protein Pathways: Hedgehog signaling pathway
• Gene Summary: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010]