PTOP (ACD) (NM_022914) Human Untagged Clone

CAT#: SC122937

ACD (untagged)-Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACD
• Synonyms: PIP1; PTOP; TINT1; TPP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022914 edited
  AAGGAAGTACCATTTATTTAGCGCTGTGTGTGTGCTCTTATTTCCACTGGCCTTACAAGA
  CCGTGCACTGTGTAGATGAGGAAACTGAGTCATAATAAATATGTGCTGAACCGTTCGGGG
  GTCACACGGTGCTGAAATGGTTTCGAGTCAACTCGCTCGGACGGCACTCGGCCTCAGCCT
  CCGGCCCTGGAACCCTCTCCAGGGACGGGACCAGCCCTTGTTCTGTTCCCTACCGGTACC
  ACAGGAATCTTGACGAACGGCCCAAATGCCTGGCCGCTGTCAGAGTGACGCCGCGATGAG
  AGTAAACGGGCCAGCATCCCGTGCACCAGCGGGGTGGACCAGCGGGAGTCTGCACACAGG
  CCCCCGAGCAGGACGCCCTCGTGCGCAGGCGCGGGGTGTACGTGGGCGGGGCCTCCTCCT
  CCGGCCCCGCCCAGCGAAGGAGCTTCCTCTTCCGAGGAAAGGCGGGGCCTGGGCGCCCGC
  GGGAAACCCGGGCCCGTTGCATCCGCTGGGTGTAGCCGTGGGGATGGCAGGTTCGGGGAG
  GCTGGTCCTACGGCCCTGGATTCGGGAGCTGATTCTGGGGTCAGAGACACCCTCCAGTCC
  ACGAGCCGGGCAGCTGCTTGAGGTACTACAGGACGCCGAGGCCGCGGTCGCGGGCCCATC
  CCACGCCCCTGATACGTCCGACGTCGGGGCCACGCTGCTTGTGTCTGACGGGACCCACAG
  TGTCCGATGCCTGGTGACGCGGGAGGCCCTGGACACCTCGGACTGGGAGGAGAAGGAGTT
  CGGCTTCCGCGGGACAGAGGGCCGGCTGCTGCTGCTGCAGGACTGCGGGGTTCATGTCCA
  GGTCGCTGAGGGCGGCGCGCCCGCAGAGTTCTATCTCCAGGTGGACCGCTTCAGCCTGCT
  GCCCACGGAGCAGCCCCGGCTACGGGTGCCTGGTTGCAACCAAGACTTAGATGTTCAGAA
  AAAGCTCTATGACTGCCTTGAGGAGCACCTTTCAGAGTCCACCTCGTCCAATGCAGGCCT
  ATCACTGTCCCAGCTTCTGGATGAAATGCGGGAGGACCAGGAGCATCAGGGGGCACTCGT
  GTGCCTGGCTGAAAGCTGCCTGACACTGGAGGGCCCTTGCACAGCACCCCCTGTCACCCA
  CTGGGCTGCCTCACGATGCAAGGCCACGGGAGAAGCTGTGTACACTGTCCCCAGCTCAAT
  GCTGTGCATCTCTGAGAATGACCAGCTAATTCTGAGCTCTCTAGGCCCCTGTCAGAGGAC
  ACAGGGCCCTGAGCTGCCCCCACCAGACCCGGCTCTGCAGGACCTATCTCTGACCCTCAT
  AGCCTCTCCTCCTTCCTCACCCAGTTCCTCAGGAACCCCGGCCTTACCCGGCCACATGTC
  ATCCGAGGAAAGTGGTACCAGCATCAGCCTTCTGCCTGCCCTGTCCTTGGCTGCTCCAGA
  CCCAGGGCAGAGAAGCAGCTCCCAGCCCTCACCAGCCATCTGCTCAGCCCCTGCCACCCT
  GACCCCCAGGTCCCCACACGCCAGCCGTACCCCCAGCTCCCCACTCCAGAGCTGCACTCC
  CAGTCTCTCACCCCGTAGCCATGTCCCCAGTCCACACCAGGCTCTTGTGACCAGGCCCCA
  GAAACCTAGCCTGGAGTTCAAGGAGTTTGTAGGGTTGCCCTGCAAGAATCGGCCGCCTTT
  TCCCAGGACCGGAGCTACCAGGGGAGCCCAGGAGCCCTGCTCTGTCTGGGAACCCCCAAA
  GAGGCATCGTGATGGTTCTGCCTTCCAGTATGAGTATGAGCCACCCTGCACGTCCCTCTG
  TGCTCGGGTCCAAGCTGCCAGGCTTCCTCCCCAGCTCATGGCCTGGGCCTTGCACTTTCT
  GATGGATGCACAGCCAGGGTCTGAGCCAACTCCGATGTGAGACGTCACGCAGGACAGATA
  CCGCTCCACACTCTGCTTCCTTTGAGTTTTTTAATAAAATAATCTCATGCGGCAAAAAAA
  AAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022914 unedited
  TCACTATAGGGCGGCCGCGCATTCCCGGGATATCGTCGACCCACGCGTCCGAAGAAGTAC
  CATTTATTTAGCGCTGTGTGTGTGCTCTTATTTCCACTGGCCTTACAAGACCGTGCACTG
  TGTAGATGAGGAAACTGAGTCATAATAAATATGTGCTGAACCGTTCGGGGGTCACACGGT
  GCTGAAATGGTTTCGAGTCAACTCGCTCGGACGGCACTCGGCCTCAGCCTCCGGCCCTGG
  AACCCTCTCCAGGGACGGGACCAGCCCTTGTTCTGTTCCCTACCGGTACCACAGGAATCT
  TGACGAACGGCCCAAATGCCTGGCCGCTGTCAGAGTGACGCCGCGATGAGAGTAAACGGG
  CCAGCATCCCGTGCACCAGCGGGGTGGACCAGCGGGAGTCTGCACACAGGCCCCCGAGCA
  GGACGCCCTCGTGCGCAGGCGCGGGGTGTACGTGGGCGGGGCCTCCTCCTCCGGCCCCGC
  CCAGCGAAGGAGCTTCCTCTTCCGAGGAAAGGCGGGGCCTGGGCGCCCGCGGGAAACCCG
  GGCCCGTTGCATCCGCTGGGTGTAGCCGTGGGGATGGCAGGTTCGGGGAGGCTGGTCCTA
  CGGCCCTGGATTCGGGAGCTGATTCTGGGGTCAGAGACACCCTCCAGTCCACGAGCCGGG
  CAGCTGCTTGAGGTACTACAGGACGCCGAGGCCGCGGTCGCGGGCCCATCCCACGCCCCT
  GATACGTCCGACGTCNGGGCCACGCTGCTTGTGTCTGACGGGACCCACAGTGTCCGATGC
  CTGGTGACGCGGGAGGCCCTGGACACCTCGGACTGGGAGGAGAAAGAGTTCGGCTTCCGC
  GGGACAGAGGCCNGCTG
  
• Restriction Sites: Please inquire
• ACCN: NM_022914
• ORF Size: 1626 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022914.1, NP_075065.1
• RefSeq Size: 2034
• RefSeq ORF: 1626
• Locus ID: 65057
• Gene Summary: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). CCDS Note: This CCDS was updated to trim the coding region at the 5' end, which shortens the N-terminus of the protein by 86 amino acid residues. The update is supported by conservation data.