alpha Tubulin (TUBA3C) (NM_079836) Human Untagged Clone

CAT#: SC123106

TUBA3C (untagged)-Human tubulin, alpha 3c (TUBA3C), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TUBA3C
• Synonyms: bA408E5.3; TUBA2; tubulin, alpha 2; tubulin, alpha 3c
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_079836 edited
  GTTGAGGTCAAGTAGTAGCGTTGGGCTGCGGCAGCGGAGGAGCTCAACATGCGTGAGTGT
  ATCTCTATCCACGTGGGGCAGGCAGGAGTCCAGATCGGCAATGCCTGCTGGGAACTGTAC
  TGCCTGGAACATGGAATTCAGCCCGATGGTCAGATGCCAAGTGATAAAACCATTGGTGGT
  GGGGACGACTCCTTCAACACGTTCTTCAGTGAGACTGGAGCTGGCAAGCACGTGCCCAGA
  GCAGTGTTTGTGGACCTGGAGCCCACTGTGGTCGATGAAGTGCGCACAGGAACCTATAGG
  CAGCTCTTCCACCCAGAGCAGCTGATCACCGGGAAGGAAGATGCGGCCAATAATTACGCC
  AGAGGCCATTACACCATCGGCAAGGAGATCGTCGACCTGGTCCTGGACCGGATCCGCAAA
  CTGGCGGATCTGTGCACGGGACTGCAGGGCTTCCTCATCTTCCACAGTTTTGGGGGTGGC
  ACTGGCTCTGGGTTCGCATCTCTGCTCATGGAGCGGCTCTCAGTGGATTACGGCAAGAAG
  TCCAAGCTAGAATTTGCCATTTACCCAGCCCCCCAGGTCTCCACGGCCGTGGTGGAGCCC
  TACAACTCCATCCTGACCACCCACACGACCCTGGAACATTCTGACTGTGCCTTCATGGTC
  GACAATGAAGCCATCTATGACATATGTCGGCGCAACCTGGACATCGAGCGTCCCACGTAC
  ACCAACCTCAATCGCCTGATTGGGCAGATCGTGTCCTCCATCACGGCCTCCCTGCGATTT
  GACGGGGCCCTGAATGTGGACTTGACGGAATTCCAGACCAACCTAGTGCCGTACCCCCGC
  ATCCACTTCCCCCTGGCCACCTACGCCCCGGTCATCTCAGCCGAGAAGGCCTACCACGAG
  CAGCTGTCCGTGGCTGAGATCACCAATGCCTGCTTCGAGCCAGCCAATCAGATGGTCAAG
  TGTGACCCTCGCCACGGCAAGTACATGGCCTGCTGCATGTTGTACAGGGGGGATGTGGTC
  CCGAAAGATGTCAACGCGGCCATCGCCACCATCAAGACCAAGCGCACCATCCAGTTTGTA
  GATTGGTGCCCAACTGGATTTAAGGTGGGCATTAACTACCAGCCCCCCACGGTGGTCCCT
  GGGGGAGACCTGGCCAAGGTGCAGCGGGCTGTGTGCATGCTGAGCAACACCACGGCCATC
  GCGGAGGCCTGGGCTCGCCTGGACCTGGCAGCTCTGGAGAAGGATTATGAAGAGGTGGGC
  GTGGATTCCGTGGAAGCCGAGGCTGAAGAAGGTGAAGAATACTGAGGGGAGGGTGTGGTG
  GGTTCTCCACTCCACTGCCACCCCCAGCGTGGCTGCTTTCAAGTTCTTTGCAATTAAAGG
  TTCTGTATAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_079836 unedited
  GGACCGCGCAATTCGGCACGAGGGTTGAGGTCAAGTAGTAGCGTTGGGCTGCGGCAGCGG
  AGGAGCTCAACATGCGTGAGTGTATCTCTATCCACGTGGGGCAGGCAGGAGTCCAGATCG
  GCAATGCCTGCTGGGAACTGTACTGCCTGGAACATGGAATTCAGCCCGATGGTCAGATGC
  CAAGTGATAAAACCATTGGTGGTGGGGACGACTCCTTCAACACGTTCTTCAGTGAGACTG
  GAGCTGGCAAGCACGTGCCCAGAGCAGTGTTTGTGGACCTGGAGCCCACTGTGGTCGATG
  AAGTGCGCACAGGAACCTATAGGCAGCTCTTCCACCCAGAGCAGCTGATCACCGGGAAGG
  AAGATGCGGCCAATAATTACGCCAGAGGCCATTACACCATCGGCAAGGAGATCGTCGACC
  TGGTCCTGGACCGGATCCGCAAACTGGCGGATCTGTGCACGGGACTGCAGGGCTTCCTCA
  TCTTCCACAGTTTTGGGGGTGGCACTGGCTCTGGGTTCGCATCTCTGCTCATGGAGCGGC
  TCTCAGTGGATTACGGCAAGAAGTCCAAGCTAGAATTTGCCATTTACCCAGCCCCCCAGG
  TCTCCACGGCCGTGGTGGAGCCCTACAACTCCATCCTGACCACCCACACGACCCTGGAAC
  ATTCTGACTGTGCCTTCATGGTCGACAATGAAGCCATCTATGACATATGTCGGCGCAACC
  TGGACATCGAGCGTCCCACGTACACCAACCTCAATCGCCTGATTGGGCAGATCGTGTCCT
  CCATCACGGCCTCCCTGCGATTTGACGGGGCCCTGAATAGTGACTT
  
• Restriction Sites: Please inquire
• ACCN: NM_079836
• Insert Size: 1416 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_079836.1, NP_524575.1
• RefSeq Size: 1408 bp
• RefSeq ORF: 1257 bp
• Locus ID: 7278
• Cytogenetics: 13q12.11
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection
• Gene Summary: 'Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) uses alternative splicing, which results in a missing internal segment compared to variant 1. The encoded isoform (2) has identical termini to the full-length isoform but is missing an internal 32 residues near the C-terminus.