Livin (BIRC7) (NM_139317) Human Untagged Clone

CAT#: SC123167

BIRC7 (untagged)-Human baculoviral IAP repeat containing 7 (BIRC7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BIRC7
• Synonyms: KIAP; LIVIN; ML-IAP; MLIAP; RNF50
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_139317 edited
  GTCTGGTGGCAGGCCTGTGCCTATCCCTGCTGTCCCCAGGGTGGGCCCCGGGGGTCAGGA
  GCTCCAGAAGGGCCAGCTGGGCATATTCTGAGATTGGCCATCAGCCCCCATTTCTGCTGC
  AAACCTGGTCAGAGCCAGTGTTCCCTCCATGGGACCTAAAGACAGTGCCAAGTGCCTGCA
  CCGTGGACCACAGCCGAGCCACTGGGCAGCCGGTGATGGTCCCACGCAGGAGCGCTGTGG
  ACCCCGCTCTCTGGGCAGCCCTGTCCTAGGCCTGGACACCTGCAGAGCCTGGGACCACGT
  GGATGGGCAGATCCTGGGCCAGCTGCGGCCCCTGACAGAGGAGGAAGAGGAGGAGGGCGC
  CGGGGCCACCTTGTCCAGGGGGCCTGCCTTCCCCGGCATGGGCTCTGAGGAGTTGCGTCT
  GGCCTCCTTCTATGACTGGCCGCTGACTGCTGAGGTGCCACCCGAGCTGCTGGCTGCTGC
  CGGCTTCTTCCACACAGGCCATCAGGACAAGGTGAGGTGCTTCTTCTGCTATGGGGGCCT
  GCAGAGCTGGAAGCGCGGGGACGACCCCTGGACGGAGCATGCCAAGTGGTTCCCCAGCTG
  TCAGTTCCTGCTCCGGTCAAAAGGAAGAGACTTTGTCCACAGTGTGCAGGAGACTCACTC
  CCAGCTGCTGGGCTCCTGGGACCCGTGGGAAGAACCGGAAGACGCAGCCCCTGTGGCCCC
  CTCCGTCCCTGCCTCTGGGTACCCTGAGCTGCCCACACCCAGGAGAGAGGTCCAGTCTGA
  AAGTGCCCAGGAGCCAGGAGGGGTCAGTCCAGCCCAGGCCCAGAGGGCGTGGTGGGTTCT
  TGAGCCCCCAGGAGCCAGGGATGTGGAGGCGCAGCTGCGGCGGCTGCAGGAGGAGAGGAC
  GTGCAAGGTGTGCCTGGACCGCGCCGTGTCCATCGTCTTTGTGCCGTGCGGCCACCTGGT
  CTGTGCTGAGTGTGCCCCCGGCCTGCAGCTGTGCCCCATCTGCAGAGCCCCCGTCCGCAG
  CCGCGTGCGCACCTTCCTGTCCTAGGCCAGGTGCCATGGCCGGCCAGGTGGGCTGCAGAG
  TGGGCTCCCTGCCCCTCTCTGCCTGTTCTGGACTGTGTTCTGGGCCTGCTGAGGATGGCA
  GAGCTGGTGTCCATCCAGCACTGACCAGCCCTGATTCCCCGACCACCGCCCAGGGTGGAG
  AAGGAGGCCCTTGCTTGGCGTGGGGGATGGCTTAACTGTACCTGTTTGGATGCTTCTGAA
  TAGAAATAAAGTGGGTTTTCCCTGGAGGTAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139317 unedited
  NGAAGCGTACAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTC
  TGGTGGCAGGCCTGTGCCTATCCCTGCTGTCCCCAGGTGGGCCCCGGGGGTCAGGAGCTC
  CAGAAGGGCCAGCTGGGCATATTCTGAGATTGGCCATCAGCCCCCATTTCTGCTGCAAAC
  CTGGTCAGAGCCAGTGTTCCCTCCATGGGACCTAAAGACAGTGCCAAGTGCCTGCACCGT
  GGACCACAGCCGAGCCACTGGGCAGCCGGTGATGGTCCCACGCAGGAGCGCTGTGGACCC
  CGCTCTCTGGGCAGCCCTGTCCTAGGCCTGGACACCTGCAGAGCCTGGGACCACGTGGAT
  GGGCAGATCCTGGGCCAGCTGCGGCCCCTGACAGAGGAGGAAGAGGAGGAGGGCGCCGGG
  GCCACCTTGTCCAGGGGGCCTGCCTTCCCCGGCATGGGCTCTGAGGAGTTGCGTCTGGCC
  TCCTTCTATGACTGGCCGCTGACTGCTGAGGTGCCACCCGAGCTGCTGGCTGCTGCCGGC
  TTCTTCCACACAGGCCATCAGGACAAGGTGAGGTGCTTCTTCTGCTATGGGGGCCTGCAG
  AGCTGGAAGCGCGGGGACGACCCCTGGACGGAGCATGCCAAGTGGTTCCCCAGCTGTCAG
  TTCCTGCTCCGGTCAAAAGGAAGAGACTTTGTCCACAGTGTGCAGGAGACTCACTCCCAG
  CTGCTGGGCTCCTGGGACCCGTGGGAAGAACCGGAAGACGCAGCCCCTGTGGCCCCCTCC
  GTCCCTGCCTCTGGGTACCCTGAGCTGCCCACACCCAGGAGAGAGGTCCAGTTCTGAAGT
  GCCCAGGAGCCAGGAGGGGTCAATCCAGCCCAGGCCCANAGGGCGTGGTGGGTTCCTGAA
  CC
  
• Restriction Sites: Please inquire
• ACCN: NM_139317
• ORF Size: 897 bp
• Insert Size: 1312
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_139317.1, NP_647478.1
• RefSeq Size: 1322
• RefSeq ORF: 897
• Locus ID: 79444
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) encodes the longer isoform (alpha). Isoform alpha protects cells from staurosporine-induced apoptosis.