LTC4S (NM_145867) Human Untagged Clone

CAT#: SC123235

LTC4S (untagged)-Human leukotriene C4 synthase (LTC4S)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LTC4S
• Synonyms: MGC33147
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_145867 edited
  CTTCCTCTCCTGGGCCGTCCTCTGAGCAGCAGACGGGGCTAAGCGTTCCCCAGCTCGCCT
  TCACACACAGCCCGTGCCACCACACCGACGGTACCATGAAGGACGAGGTAGCTCTACTGG
  CTGCTGTCACCCTCCTGGGAGTCCTGCTGCAAGCCTACTTCTCCCTGCAGGTGATCTCGG
  CGCGCAGGGCCTTCCGCGTGTCGCCGCCGCTCACCACCGGCCCACCCGAGTTCGAGCGCG
  TCTACCGAGCCCAGGTGAACTGCAGCGAGTACTTCCCGCTGTTCCTCGCCACGCTCTGGG
  TCGCCGGCATCTTCTTTCATGAAGGGGCGGCGGCCCTGTGCGGCCTGGTCTACCTGTTCG
  CGCGCCTCCGCTACTTCCAGGGCTACGCGCGCTCCGCGCAGCTCAGGCTGGCACCGCTGT
  ACGCGAGCGCGCGCGCCCTCTGGCTGCTGGTGGCGCTGGCTGCGCTCGGCCTGCTCGCCC
  ACTTCCTCCCGGCCGCGCTGCGCGCCGCGCTCCTCGGACAGCTCCGGACGCTGCTGCCGT
  GGGCCTGAGACCAAGGCCCCCGGGCCGACGGAGCCGGGAAAGAAGAGCCGGAGCCTCCAG
  CTGCCCCGGGGAGGGGCGCTCGCTTCCGCATCCTAGTCTCTATCATTAAAGTTCTAGTGA
  CCGAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145867 unedited
  TCGGGTTGNGATTTGTATACGACTCCTATGGGCGGCCGCATAACTTCGTTAGCATACATT
  ATACGAATTATGGCTCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGCTTCCTC
  TCCTGGGCCGTCCTCTGAGCAGCAGACGGGGCTAAGCGTTCCCCAGCTCGCCTTCACACA
  CAGGCCGTGCCACCACACCGACGGTACCATGAAGGACGAGGTAGCTCTACTGGCTGCTGT
  CACCCTCCTGGGAGTCCTGCTGCAAGCCTACTTCTCCCTGCAGGTGATCTCGGCGCGCAG
  GGCCTTCCGCGTGTCGCCGCCGCTCACCACCGGCCCACCCGAGTTCGAGCGCGTCTACCG
  AGCCCAGGTGAACTGCAGCGAGTACTTCCCGCTGTTCCTCGCCACGCTCTGGGTCGCCGG
  CATCTTCTTTCATGAAGGGGCGGCGGCCCTGTGCGGCCTGGTCTACCTGTTCGCGCGCCT
  CCGCTACTTCCAGGGCTACGCGCGCTCCGCGCAGCTCAGGCTGGCACCGCTGTACGCGAG
  CGCGCGCGCCCTCTGGCTGCTGGTGGCGCTGGCTGCGCTCGGCCTGCTCGCCCACTTCCT
  CCCGGCCGCGCTGCGCGCCGCGCTCCTCGGACAGCTCCGGACGCTGCTGCCGTGGGCCTG
  AGACCAAGGCCCCCGGGCCGACGGAGCCGGGAAAAGAGAGCCGGAGCCTCCAGCTGCCCC
  GGGGAGGGGCGCTCGCTTCCGCATCCTAGTCTCTATCATTAAAGNTCTAGTGACCGAAAA
  AAAAAAAAAACTCTNCTGCGCTGGATCCCGCCATNAGGGCCTGATCCTTCGAGGGGGGGC
  CCCGTACCGATATCAAGCTTGTCGACTCTAGATTGCGGGCCGCCGTCATAGCTTGTTCCC
  TGACAGATCCCCGGGGGGCATCCCTGTGACCCCTCCCG
  
• Restriction Sites: Please inquire
• ACCN: NM_145867
• Insert Size: 678 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_145867.1, NP_665874.1
• RefSeq Size: 680 bp
• RefSeq ORF: 453 bp
• Locus ID: 4056
• Cytogenetics: 5q35.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways
• Gene Summary: 'The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents a shorter transcript but encodes the longest isoform (1).