CCR3 (NM_178329) Human Untagged Clone

CAT#: SC123356

CCR3 (untagged)-Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2


  "NM_178329" in other vectors (6)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CCR3
Synonyms CC-CKR-3; CD193; CKR3; CMKBR3
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_178329 edited
TGCTGGGCGAATCCCTTTCTTGTCTGGTTCATTTGGACCCTCCAAAGCCCACAGGCTGGA
ACGGCTGAGTCATCCAAACAAAAAAGGTGGCAGCCCATCCCTCCCCCAGGAGCTCTACCC
TGTCTCAAGTAGGTGCTACCCTGTTGCTGGTGGCTGGCTGGAATTCCAAGCCAGTTGATC
TTATCCTGTGAGGTCCCTTGGAAGTGGGGCCCACAGACTGACGCTGCTCTGCTTCCTGGA
TTCAGCCCTCTTCCTAAGGAGCTCATGGACCCTGGCCGTCATCAGGTTCAACCTCATATT
CAACTGCTGGGCCTTGTCTTCTGGCCACACACTCTCTCCAAATCAGCGATGGTGGGGAAC
TGAGGAGCCAGAGGCCATTGTGGAAGAACTCCAAGAAAACAATCTCCAGGTTATCACATC
TAAAGCCTGAGCAAGATTTGAGGCTGGGAAGAGGTGGATCCCAGAATTGGAAGAAGGAGT
GGTGATGCCTAAGCTATCACTGGACATATCAAGGACTTCACTAAATTAGCAGGGAGAAGT
GAAATGACAACCTCACTAGATACAGTTGAGACCTTTGGTACCACATCCTACTATGATGAC
GTGGGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGCCCAGTTTGTGCCCCCG
CTGTACTCCCTGGTGTTCACTGTGGGCCTCTTGGGCAATGTGGTGGTGGTGATGATCCTC
ATAAAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTCAACCTGGCCATTTCG
GACCTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTCAGGGGGCATAACTGG
GTTTTTGGCCATGGCATGTGTAAGCTCCTCTCAGGGTTTTATCACACAGGCTTGTACAGC
GAGATCTTTTTCATAATCCTGCTGACAATCGACAGGTACCTGGCCATTGTCCATGCTGTG
TTTGCCCTTCGAGCCCGGACTGTCACTTTTGGTGTCATCACCAGCATCGTCACCTGGGGC
CTGGCAGTGCTAGCAGCTCTTCCTGAATTTATCTTCTATGAGACTGAAGAGTTGTTTGAA
GAGACTCTTTGCAGTGCTCTTTACCCAGAGGATACAGTATATAGCTGGAGGCATTTCCAC
ACTCTGAGAATGACCATCTTCTGTCTCGTTCTCCCTCTGCTCGTTATGGCCATCTGCTAC
ACAGGAATCATCAAAACGCTGCTGAGGTGCCCCAGTAAAAAAAAGTACAAGGCCATCCGG
CTCATTTTTGTCATCATGGCGGTGTTTTTCATTTTCTGGACACCCTACAATGTGGCTATC
CTTCTCTCTTCCTATCAATCCATCTTATTTGGAAATGACTGTGAGCGGAGCAAGCATCTG
GACCTGGTCATGCTGGTGACAGAGGTGATCGCCTACTCCCACTGCTGCATGAACCCGGTG
ATCTACGCCTTTGTTGGAGAGAGGTTCCGGAAGTACCTGCGCCACTTCTTCCACAGGCAC
TTGCTCATGCACCTGGGCAGATACATCCCATTCCTTCCTAGTGAGAAGCTGGAAAGAACC
AGCTCTGTCTCTCCATCCACAGCAGAGCCGGAACTCTCTATTGTGTTTTAGGTCAGATGC
AGAAAATTGCCTAAAGAGGAAGGACCAAGGAGATGAAGCAAACACATTAAGCCTTCCACA
CTCACCTCTAAAACAGTCCTTCAAACTTCCAGTGCAACACTGAAGCTCTTGAAGACACTG
AAATATACACACAGCAGTAGCAGTAGATGCATGTACCCTAAGGTCATTACCACAGGCCAG
GGGCTGGGCAGCGTACTCATCATCAACCCTAAAAAGCAGAGCTTTGCTTCTCTCTCTAAA
ATGAGTTACCTACATTTTAATGCACCTGAATGTTAGATAGTTACTATATGCCGCTACAAA
AAGGTAAAACTTTTTATATTTTATACATTAACTTCAGCCAGCTATTGATATAAATAAAAC
ATTTTCACACAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_178329 unedited
GGGGACGTTTGGATTTTGTAATACGACTTACTATAGGGNNCGGCCGCGCAATTCCAAGCC
AGTTGATCTTATCCTGTGAGGTCCCTTGGAAGTGGGGCCCACAGACTGACGCTGCTCTGC
TTCCTGGATTCAGCCCTCTTCCTAAGGAGCTCATGGACCCTGGCCGTCATCAGGTTCAAC
CTCATATTCAACTGCTGGGCCTTGTCTTCTGGCCACACACTCTCTCCAAATCAGCGATGG
TGGGGAACTGAGGAGCCAGAGGCCATTGTGGAAGAACTCCAAGAAAACAATCTCCAGGTT
ATCACATCTAAAGCCTGAGCAAGATTTGAGGCTGGGAAGAGGTGGATCCCAGAATTGGAA
GAAGGAGTGGTGATGCCTAAGCTATCACTGGACATATCAAGGACTTCACTAAATTAGCAG
GGAGAAGTGAAATGACAACCTCACTAGATACAGTTGAGACCTTTGGTACCACATCCTACT
ATGATGACGTGGGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGCCCAGTTTG
TGCCCCCGCTGTACTCCCTGGTGTTCACTGTGGGCCTCTTNGGCAATGTGGTGGTGGTGA
TGATCCTCATAAAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTCAACCTGG
CCATTTCGGACCTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTCAGGGGGC
ATAACTGGGTTTTTGGCCATGGCATGTGTAAGCTCCTCTCAAGGTTTATCACACAGGCTT
GTACAGCGAGATCCTTTTTCATATCCTGCTGACAATCGACAGGTACCTGGCCATTTGTCA
TGCTGTGTTTGCCCTTCAAGCCCGACTGTCACTTTTGGTGTCATCACCAGCATCTTCACC
TGG
Restriction Sites Please inquire     
ACCN NM_178329
Insert Size 2030 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_178329.1, NP_847899.1
RefSeq Size 1866 bp
RefSeq ORF 1068 bp
Locus ID 1232
Cytogenetics 3p21.31
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Gene Summary 'The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]'
Transcript Variant: This variant (2) lacks an internal exon in the 5' UTR, as compared to variant 1. Both variants encode the same isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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