TMEM16A (ANO1) (BC033036) Human Untagged Clone

CAT#: SC123484

ANO1 (untagged)-Human transmembrane protein 16A (cDNA clone MGC:33580 IMAGE:4823645), complete cds


Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ANO1
Synonyms anoctamin 1, calcium activated chloride; FLJ10261; membrane protein; oral cancer overexpressed 2; ORAOV2; TAOS2; TMEM16A; transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor amplified and overexpressed sequence 2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for BC033036 edited
AGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCGGC
ACCAAATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCC
TAGGGCCAGAGAGGCCAAGGTGCCAGGGACATGGCCCCAACTGTCCCCTAACCAGGGGTA
GAGGAGTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTA
CATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCCTGGTCAGGAGGGTGCA
GCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCAGGGGAGCCCCCGATGGACTACCACGAGGATGACAA
GCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGGGCCTGGAGCTGGAGCG
GGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACAT
TAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCCAGAAAATCACAGATCC
CATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAA
AACCCGGAGCACGATTGTCTATGAGATCTTGAAGAGAACGACGTGTACAAAGGCCAAGTA
CAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA
CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGA
GTGGGCACGCTATGGAGTTTTCTATAAGTACCAGCCCATCGACCTGGTCAGGAAGTATTT
TGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC
TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACAT
CCCCAGCATGGAGATGTGTGACCAGAGACACAATATCACCATGTGCCCGCTTTGCGACAA
GACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT
CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCAT
GGAGCACTGGAAGCGGAAACAGATGCGACTCAACTACCGCTGGGACCTCACGGGCTTTGA
AGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCAAGAGTCTTGGAGAAGTCTCTGAA
GAAAGAGTCTAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCC
AGCCTACCTCACTAACTTGGTCTCCATCATCTTCATGATTGCAGTGACGTTTGCCATCGT
CCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC
CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGT
GGTCATCATCCTCCTGGACGAGGTGTATGGCTGCATAGCCCGATGGCTCACCAAGATCGA
GGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA
GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGG
ACGCCCGGGCGACTACGTGTACATTTTCCGTTCCTTCCGAATGGAAGAGTGTGCGCCAGG
GGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT
CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAA
GCTGAAGCAGCAGAGCCCCCCTGACCACGAGGAGTGTGTGAAGAGGAAACAGCGGTACGA
GGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT
CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCT
GCTGAACAACATCATCGAGATCCGCCTGGACGCCAAAAAGTTTGTCACTGAGCTCCGAAG
GCCGGTAGCTGTCAGAGCCAAAGACATCGGAATCTGGTACAATATCCTCAGAGGCATTGG
GAAGCTTGCTGTCATCATCGATGCCTTCGTGATCTCCTTCACGTCTGACTTCATCCCGCG
CCTGGTGTACCTCTACATGTACAGTAAGAACGGGACCATGCACGGCTTCGTCAACCACAC
CCTCTCCTCCTTCAACGTCAGTGACTTCCAGAACGGCACGGCCCCCAATGACCCCCTGGA
CCTGGGCTACGAGGTGCAGATCTGCAGGTATAAAGACTACCGAGAGCCGCCGTGGTCGGA
AAACAAGTACGACATCTCCAAGGACTTCTGGGCCGTCCTGGCAGCCCGGCTGGCGTTTGT
CATCGTCTTCCAGAACCTGGTCATGTTCATGAGCGACTTTGTGGACTGGGTCATCCCGGA
CATCCCCAAGGACATCAGCCAGCAGATCCACAAGGAGAAGGTGCTCATGGTGGAGCTGTT
CATGCGGGAGGAGCAAGACAAGCAGCAGCTGCTGGAAACCTGTATGGAGAAGGAGCGGCA
GAAGGACGAGCCGCCGTGCAACCACCACAACACCAAAGCCTGCCCAGACAGCCTCGGCAG
CCCAGCCCCCAGCCATGCCTACCACGGGGGCGTCCTGTAGCTATGCCAGCGGGGCTGGGC
AGGCCAGCCGGGCATCCTGACCGATGGGCACCCTCTCCCAGGGCAGGCGGCTTCCCGCTC
CCACCAGGGCCCGGAATGTCACTGTTGGACAATTATTTTAAAAGTGTATAAAACCAAGTC
TCATAAATGATATGAGTGATCTAAATTTGCAGCAATGATACTAAACAACTCTCTGAAATT
TCTCAAGCACCAAGAGAAACATCATTTTAGCAAAGGCCAGGAGGAAAAATAGAAATAAAT
TTGTCTTGAAGATCCCAAAAAAAAAAAAAAAA
>OriGene 5' read for BC033036 unedited
NAGAGTCTGTATTTGTATACGACTTCTATAGGCGGCCGCATAACTTCGTATAGCATACAT
TATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGCGG
GGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCGGCACCAA
ATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCCTAGGG
CCAGAGAGGCCAAGGTGCCAGGGACATGGCCCCAACTGTCCCCTAACCAGGGGTAGAGGA
GTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTGGACCCTG
ATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCC
TGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACA
GCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGG
CGTCGCTGGATGCAGGCTCATGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCT
TCCGCANGGAGGAGTACGAGGGCAACCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACG
AGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGT
GCANAGAGGCCCAGTTTCCTGAAAACTCGGAAAAAAGGCCCCCCCCCCCCNNGGNNNNNT
NGGGGNGGGAGAGGGGAGAGGGGGTTATGGGACTTCCCGAATTGTGACTTTCCCTCTTTC
TGCCCCACGCNCCTTAAAACGTAGTGTGTTGCCGGGGTGGGGCCCGCGCCACGATA
Restriction Sites Please inquire     
ACCN BC033036
ORF Size 2520 bp
Insert Size 3277
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC033036.2, AAH33036.2
RefSeq Size 3272
RefSeq ORF 2520
Locus ID 55107
Protein Families Transmembrane
Gene Summary Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. [UniProtKB/Swiss-Prot Function]

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