ACK1 (TNK2) (BC008884) Human Untagged Clone

CAT#: SC123716

TNK2 (untagged)-Homo sapiens, Similar to activated p21cdc42Hs kinase, clone MGC:15139 IMAGE:4302390, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TNK2
• Synonyms: p21cdc42Hs
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC008884 edited
  GGCACGAGGGGGATTTGGGGGGCTCCTGGGCAGAGTGCGAAGCTCCGGAGCCGAGGCCAC
  TGGATCCCCAGTGACTGCTCGGGGGGGTCCCGCTGCGTGGAGATGCCGGCAGCACGTCGG
  TTCCCTGGCCTGGAGCTCTCCTTCCCTCTCCTGGCCAGACTGCGGCGACGCCTGTACACA
  AGGCTGGGAGGCGGCAGAATGCAGCCAGAGGAGGGCACAGGCTGGCTGCTGGAGCTGCTG
  TCCGAGGTGCAGCTGCAACAGTACTTCCTGCGGCTCCGAGATGACCTCAACGTCACCCGC
  CTGTCCCACTTTGAGTACGTCAAGAATGAGGACCTGGAGAAGATCGGCATGGGTCGGCCT
  GGCCAGCGGCGGCTGTGGGAGGCTGTGAAGAGGAGGAAGGCCTTGTGCAAACGCAAGTCG
  TGGATGAGTAAGGTGTTCAGTGGAAAGCGACTGGAGGCTGAGTTCCCACCTCATCACTCT
  CAGAGCACCTTCCGGAAGACCTCGCCCGCCCCTGGGGGCCCAGCAGGGGAGGGGCCCCTG
  CAGAGCCTCACCTGCCTCATTGGGGAGAAGGACCTGCGCCTCCTGGAGAAGCTGGGTGAT
  GGTTCCTTTGTCGTGGTGCGCAGGGGCGAGTGGGACGCGCCCTCAGGGAAGACGGTGAGT
  GTGGCTGTGAAGTGCCTGAAGCCCGATGTCCTGAGCCAGCCAGAAGCCATGGACGACTTC
  ATCCGGGAGGTCAATGCCATGCACTCGCTCGACCACCGAAACCTCATCCGCCTCTACGGG
  GTGGTGCTCACGCCGCCCATGAAGATGGTGACAGAGCTGGCACCTCTGGGATCGTTGTTG
  GACCGGCTACGTAAGCACCAGGGCCACTTCCTCCTGGGGACTCTGAGCCGCTACGCTGTG
  CAGGTGGCTGAGGGCATGGGCTACCTGGAGTCCAAGCGCTTTATTCACCGTGACCTGGCT
  GCCCGCAATCTGCTGTTGGCTACCCGCGACCTGGTCAAGATCGGGGACTTTGGGCTGATG
  CGAGCACTACCTCAGAATGACGACCATTACGTCATGCAGGAACATCGCAAGGTGCCCTTC
  GCCTGGTGTGCCCCCGAGAGCCTGAAGCCGCCCTGGAGGGACATCAGTGCTTCCTCTTCC
  ACCCAATTCCCCCACGCGGTTCCATGTTTTCCCACCAGCCTGTTGGCGAAGTTGCTGCTC
  CGGCATTCAGTACCTGCTTCTTCCAGAGAAATAAAGTTAGTTTCTATTTTATGTTAAAAA
  AAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC008884 unedited
  NNNNNNNGAGTCAACATTTGTNAAACGACTCACTATAGGCGGCCGCGAATTCGCACGAGG
  GGGATTTGGGGGGCTCCTGGGCAGAGTGCGAAGCTCCGGAGCCGAGGCCACTGGATCCCC
  AGTGACTGCTCGGGGGGGTCCCGCTGCGTGGAGATGCCGGCAGCACGTCGGTTCCCTGGC
  CTGGAGCTCTCCTTCCCTCTCCTGGCCAGACTGCGGCGACGCCTGTACACAAGGCTGGGA
  GGCGGCAGAATGCAGCCAGAGGAGGGCACAGGCTGGCTGCTGGAGCTGCTGTCCGAGGTG
  CAGCTGCAACAGTACTTCCTGCGGCTCCGAGATGACCTCAACGTCACCCGCCTGTCCCAC
  TTTGAGTACGTCAAGAATGAGGACCTGGAGAAGATCGGCATGGGTCGGCCTGGCCAGCGG
  CGGCTGTGGGAGGCTGTGAAGAGGAGGAAGGCCTTGTGCAAACGCAAGTCGTGGATGAGT
  AAGGTGTTCAGTGGAAAGCGACTGGAGGCTGAGTTCCCACCTCATCACTCTCAGAGCACC
  TTCCGGAAGACCTCGCCCGCCCCTGGGGGCCCAGCAGGGGAGGGGCCCCTGCAGAGCCTC
  ACCTGCCTCATTGGGGAGAAGGACCTGCGCCTCCTGGAGAAGCTGGGTGATGGTTCCTTT
  GTCGTGGTGCGCATGGGCGAGTGGGACGCGCCCTCAGGGAAGACGGTGAGTGTGGCTGTG
  AAGTGCCTGAAGCCCGATGTCCTGAGCCAGCCAGAAGCCATGGACGACTTCATCCGGGAG
  GTCAATGCCATGCACTCGCTCGACCACCGAAACCTCATCCGCCTCTACGGAGTGGTGCTC
  ACGCCGCCCAT
  
• Restriction Sites: Please inquire
• ACCN: BC008884
• Insert Size: 1275
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC008884.1, AAH08884.1
• RefSeq Size: 1275
• Locus ID: 10188
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]