HIP2 (UBE2K) (BC006419) Human Untagged Clone

CAT#: SC123749

(untagged)-Homo sapiens, clone MGC:12679 IMAGE:3946309, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2K
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC006419 edited
  GCAGCTGGGAGGACCCTCCCGCCCCAGGCAGAGGTGGGGGATATCCGGGAGTTCATTTCT
  GACCTCCTCGCTCTTCAGCACCTCCTTGAACTCCCGCTTGATTCGCTGCACCGCGATGTT
  GGCCATGTCTCCGCCCGCAGCTGATTCGTACCCGCCTCCTCCGCCACCGCTACGACCACC
  GCCACCGCCGCCACCTCTTCCTCCACCGCCTCCTCCCTCGGCGATTCAGACCTGAGCACA
  CGAACACTGCCACTACCACCCCGGCCGCCGCGCTCGCCTCAGTGTGGAATCACCTCCGCG
  CCCGGCCACCAAAATGGCGCCGGGTCGGCGCATGCGCACGACGTTGACCCGGCCGGGCGG
  CGCAGCCGCTCCTGTTGGAGCCCCCATACGCCCGAGCCACGAGCTCGCGTCTCGGCTGGG
  GCTGCGGCCGCGTGGCTCCGCCCTGCCGGCGTCTGGGGCCGCGAGGGTGCGGCTTCCAAG
  CTGGCCGGCCCTAGCCGGCCCCCCCGGCCCTTCCCGGCGCCTCCGCTCCTGTTTAAACCC
  GGGTGCTGTGGTCTGGGCTTCCAGCGCTGGCCTCTGACCGAAGGTTCGGGCGCAACCGAA
  CGGGTTTCCGACGCCGCACTCGGCTGGAACGCCGCCCTGACTCAGCTAGACCCGGAACCC
  GGAGGCTGAACGCCGTGTCTAGCGCAGGAAAACGCTCTCCCGGATCTCGGTCCGGCCCAT
  TTTCAGTTGGTGTAGCCCCAGAAAATCTACTGCAGTCGTTTTTGTTCTGCAACATTTATA
  GTACCACGATTATTCCCATCATCTCAGGTAGCACAGATTATTGAATTAAGGCTGGTTATT
  GTTGGATCAGATTGGGTTTGAGACAGGTACTCGGTGGAGAGGCCTGAGGGTGGGTTTAGA
  AGCCAGATGTTGCTCTTTGACCTATTTAATACCGAGCTTGACACACACACACAATCTCTC
  TCTCTCTCTCTCTCTCTCACACACACACACACACACACACACTCACTCCTATGCCCATCC
  CTAGAGTGTAGGGTGGGCCTAAGACTGCGCTTCTAACAAGTCTCCCAGTTGCTGCTGCTG
  TTGGTGCTGGTTCCGGGACCACATTATGAGAACCACTGAACTGAATGAAGCATGTGAAAA
  TTCACATATATTAAAGTGAAAATTGGAGAAATGGAAACAATTACAGTACCCTTCAGGGGA
  CTCGGGGTGGGGGAGGGGGAGCCTTATTTCTGTAAACCTAGGCCTCAAAGGTGCCTGGTG
  ATAGTAGGCACTCAATAAATATTGAATGAGTAAATGAGTACAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC006419 unedited
  NAAGTACAAAATTTGTAATACGACTCACTATNAGGGCCGGCCGCGAATTCGCACGAGGGC
  AGCTGGGAGGACCCTCCCGCCCCAGGCAGAGGTGGGGGATATCCGGGAGTTCATTTCTGA
  CCTCCTCGCTCTTCAGCACCTCCTTGAACTCCCGCTTGATTCGCTGCACCGCGATGTTGG
  CCATGTCTCCGCCCGCAGCTGATTCGTACCCGCCTCCTCCGCCACCGCTACGACCACCGC
  CACCGCCGCCACCTCTTCCTCCACCGCCTCCTCCCTCGGCGATTCAGACCTGAGCACACG
  AACACTGCCACTACCACCCCGGCCGCCGCGCTCGCCTCAGTGTGGAATCACCTCCGCGCC
  CGGCCACCAAAATGGCGCCGGGTCGGCGCATGCGCACGACGTTGACCCGGCCGGGCGGCG
  CAGCCGCTCCTGTTGGAGCCCCCATACGCCCGAGCCACGAGCTCGCGTCTCGGCTGGGGC
  TGCGGCCGCGTGGCTCCGCCCTGCCGGCGTCTGGGGCCGCGAGGGTGCGGCTTCCAAGCT
  GGCCGGCCCTAGCCGGCCCCCCCGGCCCTTCCCGGCGCCTCCGCTCCTGTTTAAACCCGG
  GTGCTGTGGTCTGGGCTTCCAGCGCTGGCCTCTGACCGAAGGTTCGGGCGCAACCGAACG
  GGTTTCCGACGCCGCACTCGGCTGGAACGCCGCCCTGACTCAGCTAGACCCGGAACCCGG
  AGGCTGAACGCCGTGTCTAGCGCAAGANAACGCTCTCCCGGATCTCGGTCCGGCCCATTT
  TCAGTTGGTGTAGCCCCAGAAAATCTACTGCAGTCGTTTTTGTTCTGCACATTTATAGTA
  CCACGATTATTCCCATCATCTCAGGTAGCACAGATTATTGATTANAGCTGGGTTATGNTG
  GATCAGATGGNGTT
  
• Restriction Sites: Please inquire
• ACCN: BC006419
• Insert Size: 1343 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC006419.1
• RefSeq Size: 1343 bp
• Locus ID: 3093
• Cytogenetics: 4p14
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: 'The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'