CBR4 (BC033650) Human Untagged Clone

CAT#: SC123818

CBR4 (untagged)-Human carbonic reductase 4 (cDNA clone MGC:44889 IMAGE:5574637), complete cds

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Reconstitution Protocol

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Size
    • 10 ug
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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CBR4
Synonyms carbonic reductase 4; carbonyl reductase 4; FLJ14431; SDR45C1; short chain dehydrogenase/reductase family 45C, member 1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for BC033650 edited
CCACGCGTCCGGAGGTGTCGAGCGGCGTTATTTTTTTTTGCGGTTTGCCTTTTTTTTTCT
TTTTTTTTTTTTGGAACCGCGGTTGTTTAAAAGCCTGAGGGAACCTGGAGGGGGGCTCCC
ACTCCCTACCTTCTTTCCTCCGAGTTTGTGACTCCGAGATGGACAAAGTGTGTGCTGTTT
TTGGAGGCTCCCGAGGCATTGGCAGAGCTGTGGCCCAGTTAATGGCCCGGAAAGGCTACC
GACTGGCGGTCATTGCCAGAAACCTGGAAGGGGCCAAAGCCGCCGCCGGTGACCTCGGCG
GAGATCATTTGGCATTTAGCTGTGATGTTGCTAAAGAACATGATGTTCAAAATACATTTG
AAGAGCTGGAGAAACATTTAGGTCGAGTAAATTTCTTGGTAAATGCAGCTGGTATTAACA
GGGATGGTCTTTTAGTAAGAACAAAAACTGAAGATATGGTATCTCAGCTTCATACTAACC
TCTTGGGTTCCATGCTGACCTGTAAAGCTGCCATGAGGACTATGATTCAACAACAGGGAG
GGTCTATTGTTAATGTAGGAAGCATTGTTGGCTTAAAAGGCAACTCTGGCCAGTCCGTTT
ACAGTGCCAGTAAAGGAGGATTAGTTGGATTTTCACGTGCTCTTGCTAAAGAGGTAGCAA
GAAAGAAAATTAGAGTGAATGTAGTTGCACCAGGATTTGTACACACAGATATGACGAAAG
ACTTGAAAGAAGAACATTTAAAGAAAAATATTCCTCTTGGGAGGTTTGGAGAAACTATTG
AGGTGGCACATGCGGTTGTGTTTCTTTTAGAATCACCGTATATTACAGGGCATGTTCTGG
TAGTGGATGGGGGATTACAACTCATTTTGTAATTTGCAGATTATTCAGTTATAGGGGTGA
TTAGCATCAAGGGCACACTTTGGCTACTGATTAGACAATTATACCTACATGGGTAACATG
TGCTAATCAAACCTGCTGATGCTACAAATGTTAATTTCTGTCTTTATAAAAATATGTCTC
AAAAGAACAATGTGTGACAAATTGTGGTTTTTTTTTTTTTTGGTCTAAGTTACATCAGTG
TTGTTTTGTTTAAAAAGCCTTCATGAGATACAATTCACATACCATATAATCACACATTTA
AAATACACAATTCAGTGGTTTTAACATATTTAAATACATGTGCAATCATCCCCCCAGACA
AATTGTGTTTTCTAAAGGATGTGTATCACTTACCTTTGGTTACCTCATAGACTGTAGCAA
TCTTAGTGTATAGACATTTTGCAAGTCATATAAACAAGTATTGATTTATATATTTTGTCT
CAAAAGTGGAAAAATTATATTGTCTAATTATGATGAATTATTTTCTTGTATCAAGCTGAA
TTTTCTAAAAGTTAACCTTGTGGGCTGTTGCCAAAATAAGAGTATTTAGAGGACACTGAT
TAGTTGTCAATACTTTAGCAAGCCCACTAAAGATAACTATATTCCTTTTGCATGTGCTTG
GGTGATCAGTTTTTATACAGGTTGCAAAACATAGTATTCATTAAAGACATGAATTTAGAA
TTGATTTCTTTGAGTGGTATTTCTCTTGATTGAGCAGCTAGACAAAATAATCTGCAAATT
TAAATGTGGCGCATTTGACTCATTCTTGAGAAATTCTCATAAGTGAAGAGGATTAGCCCT
TAAGGTTTTAATACCTGGTACAGTAGTGAACCGCACAGATTTCATGAACTTAGGATGTGT
TTTTTATTCATGAAAAACTTAGAATAGTGAACTATTAATATTTAAAAACGAGAAATACAA
CATTTAAAAAATTAAGAGTATTTTGCATTAGTGATTATGATTCTTATCCCAAAATTCTAG
AAAGTAATAAATTCTGTATGAATAAGCATAAAAAATAAATAAATATGCAATAACATTAAA
TTAAATGTCTTTACAAGAAGCAGTGAAGGCACTGGTCTTAAGTGAGAATATTTGCCTGGG
AGTAGAGATAAAGACACAAACCGAATGTGAAATACCAGGTAATAATTATTTTGCATTAAA
CTCTTTTTATCGGGAATAGTATGATATTTTCAATGTCACTCCATTCATGTTGATTTGGAG
CTGACAGTTATTTTGTGTAAGCAGAGATTTAATTTTATATTGAAAGTCAGTGCAAAATTA
TGAATAGGATATACTAATAAATACAAAGTAATAACAAAAGTCAAAGCAGTGTTCTAAATA
AAAATTCTGGGTTCCTTAAAAATTATTTTAAATTTATCTTTGAAATAGTTTTCTTAGATT
AATCTCAGGATATGAGAAAGTCAATTAAGTGTGAGTAAAGTTAGTATCATTAAACAAATT
GTCTATTAAATGCAAGACGTGGTAATATACAGAATTTATCAGGCATTACCAAGTCTAGGC
ACATATAGGAAATGCAGCACTCAGAATGGTTTCAATGTAGTAGTTGATGCTTGTAAGGTA
GGGGAGCTTATTCAGACATAGTAGATAGTTTCTCTAATGCTGTCTCAATTGCTGGCCTTT
GGCTACCTGTACTTCCCCATTATGGCAGCCCATTCAGTCTTGAGTTTTCTTCTCTGGACA
CCTTATGCTCTGAAATCATGAGCGAGGCTGATTCAATTGGTGATTTGGGTAGAAAGCAGT
ATGTTTTGCTGACATTAAGATGTAGGTTATAGATAGGTTTAGCCTTTAAGTGTATGTTTT
TATACTTTAAAATAAGAAATATAACCTTTTAAGCTATTCCACCTCCTCCCCCAGCCTATC
TCAAACTGGTGGAATATATGGAGAGATCTTGAAAGAGGTAAAATAAACCTTCACTGCTCC
ACTCCAGGTGAATCCGCCCACTCCCACTGACCTAGTAGAATTTGTAATTTAATACTTACC
TTCTATTTCTGAAATCAGTTGTGAACTGTTGCCTTATGTTCAGAGGTTTAAGAACCTCAG
TGAATTCATTTTTTAAAATCTGCTATTCTGAGAAGCATTGAATGAATTCTTAACAAGAAG
ACTCATCTGTAGCTGTTTGCTGACTCCTATGAGCCCATAAGGGTTCTGTGCTTAGCATTA
ACAAAATAAGGTTTATAGGTAAAGCCAATGTATTAATTTTTTTTTGCATGGAGGGCTTTA
AAATTTGTGCTCTTTTTCATATTTTATTCATATTCAATTTATGGTTTGTAACTGCTTTTT
AGGGAGATAATTATATGTTATAAATTAGTTTTGGGGGGAATAATTGTGCAAAGAGGATAA
TTTAATTTACGTGCTTCTGTTATTCAGAATAAAGAGAGAAGACTACGCTGCATATTCAAG
AGTTGTACCTTAACATTGGTGAAACATTTTTTTCTAAGATTTTCAAAAGGAATATGTGTA
AATTGAGAAATCATAACCACTGTCCTAACTTGGTAAACAAACTGTTCTTAAATAAAGTAT
TTAATGATTTTAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for BC033650 unedited
GTCACTACCCTGAGCCGCCATCCCGCTGTTTTGACCTCCATATAAGACCCGGGACCGATC
CAGCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCT
ATGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTG
GTACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGAGGTGTCGAGCGGCG
TTATTTTTTTTTGCGGTTTGCCTTTTTTTTTCTTTTTTTTTTTTTGGAACCGCGGTTGTT
TAAAAGCCTGAGGGAACCTGGAGGGGGGCTCCCACTCCCTACCTTCTTTCCTCCGAGTTT
GTGACTCCGAGATGGACAAAGTGTGTGCTGTTTTTGGAGGCTCCCGAGGCATTGGCAGAG
CTGTGGCCCAGTTAATGGCCCGGAAAGGCTACCGACTGGCGGTCATTGCCAGAAACCTGG
AAGGGGCCAAAGCCGCCGCCGGTGACCTCGGCGGAGATCATTTGGCATTTAGCTGTGATG
TTGCTAAAGAACATGATGTTCAAAATACATTTGAAGAGCTGGAGAAACATTTAGGTCGAG
TAAATTTCTTGGTAAATGCAGCTGGTATTAACAGGGATGGTCTTTTAGTAAGAACAAAAA
CTGAAGATATGGTATCTCAGCTTCATACTAACCTCTTGAGTTCCATGCTGACCTGTAAAG
CTGNCCATGAGACTATGATTCAACACAGGGAGGNTCTATTGNTAATGTANGAAGCATGNT
GGCTTAAAAGGCACTCTGGCCAGTCCGTTACAGTGCCAGTAAAGGNAGATTAGTTGGATT
TTCACGTGCTCTTGCTAAAGAGTAGCAGGAAGAAATTGAGTGAATGTAGTTGCACCAGGA
TTTGTCACACAGATATGACGGAAGACT
Restriction Sites Please inquire     
ACCN BC033650
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC033650.1, AAH33650.1
RefSeq Size 3452
Locus ID 84869
Protein Families Druggable Genome
Gene Summary The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508). [UniProtKB/Swiss-Prot Function]

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