FGFRL1 (NM_021923) Human Untagged Clone

CAT#: SC123844

FGFRL1 (untagged)-Human fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FGFRL1
• Synonyms: FGFR-5; FGFR5; FHFR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123844 sequence for NM_021923 edited (data generated by NextGen Sequencing)
  
  
  ATGACGCCGAGCCCCCTGTTGCTGCTCCTGCTGCCGCCGCTGCTGCTGGGGGCCTTCCCGCCGGCCGCCG
  CCGCCCGAGGCCCCCCAAAGATGGCGGACAAGGTGGTCCCACGGCAGGTGGCCCGGCTGGGCCGCACTGT
  GCGGCTGCAGTGCCCAGTGGAGGGGGACCCGCCGCCGCTGACCATGTGGACCAAGGATGGCCGCACCATC
  CACAGCGGCTGGAGCCGCTTCCGCGTGCTGCCGCAGGGGCTGAAGGTGAAGCAGGTGGAGCGGGAGGATG
  CCGGCGTGTACGTGTGCAAGGCCACCAACGGCTTCGGCAGCCTGAGCGTCAACTACACCCTCGTCGTGCT
  GGATGACATTAGCCCAGGGAAGGAGAGCCTGGGGCCCGACAGCTCCTCTGGGGGTCAAGAGGACCCCGCC
  AGCCAGCAGTGGGCACGACCGCGCTTCACACAGCCCTCCAAGATGAGGCGCCGGGTGATCGCACGGCCCG
  TGGGTAGCTCCGTGCGGCTCAAGTGCGTGGCCAGCGGGCACCCTCGGCCCGACATCACGTGGATGAAGGA
  CGACCAGGCCTTGACGCGCCCAGAGGCCGCTGAGCCCAGGAAGAAGAAGTGGACACTGAGCCTGAAGAAC
  CTGCGGCCGGAGGACAGCGGCAAATACACCTGCCGCGTGTCGAACCGCGCGGGCGCCATCAACGCCACCT
  ACAAGGTGGATGTGATCCAGCGGACCCGTTCCAAGCCCGTGCTCACAGGCACGCACCCCGTGAACACGAC
  GGTGGACTTCGGGGGGACCACGTCCTTCCAGTGCAAGGTGCGCAGCGACGTGAAGCCGGTGATCCAGTGG
  CTGAAGCGCGTGGAGTACGGCGCCGAGGGCCGCCACAACTCCACCATCGATGTGGGCGGCCAGAAGTTTG
  TGGTGCTGCCCACGGGTGACGTGTGGTCGCGGCCCGACGGCTCCTACCTCAATAAGCTGCTCATCACCCG
  TGCCCGCCAGGACGATGCGGGCATGTACATCTGCCTTGGCGCCAACACCATGGGCTACAGCTTCCGCAGC
  GCCTTCCTCACCGTGCTGCCAGACCCAAAACCGCCAGGGCCACCTGTGGCCTCCTCGTCCTCGGCCACTA
  GCCTGCCGTGGCCCGTGGTCATCGGCATCCCAGCCGGCGCTGTCTTCATCCTGGGCACCCTGCTCCTGTG
  GCTTTGCCAGGCCCAGAAGAAGCCGTGCACCCCCGCGCCTGCCCCTCCCCTGCCTGGGCACCGCCCGCCG
  GGGACGGCCCGCGACCGCAGCGGAGACAAGGACCTTCCCTCGTTGGCCGCCCTCAGCGCTGGCCCTGGTG
  TGGGGCTGTGTGAGGAGCATGGGTCTCCGGCAGCCCCCCAGCACTTACTGGGCCCAGGCCCAGTTGCTGG
  CCCTAAGTTGTACCCCAAACTCTACACAGACATCCACACACACACACACACACACTCTCACACACACTCA
  CACGTGGAGGGCAAGGTCCACCAGCACATCCACTATCAGTGCTAG
  
  Clone variation with respect to NM_021923.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021923 unedited
  CTCATGCAAGACACCGGGACCGATCCATCCTCCGGACTCTATCCTAGGCCGCGGGACGGA
  TAACAATTTCACACAGGAAACAGCTATGACCATTAGGCCTATTTAGGTGACACTATAGAA
  CAAGTTTGTACAAAAAAGCAGGCTGGTACCGGTCCGGAATTCCCGGGATCCCTTCTGTTT
  TTAGAGAGCGGTCTGGGCCCGGCCCGGGGCTGCGCAGAGGTCAGACTGCCGCGGGCAGGG
  CCGGAGCCTGCTCTGGGGGTCGCGGAGGTGTCTCGAGAGTTGAGGACCCGACCCGGGCGC
  GCGCGGGCGCAGGTCCGGACAGGCCGAGATGACGCCGAGCCCCCTGTTGCTGCTCCTGCT
  GCCGCCGCTGCTGCTGGGGGCCTTCCCGCCGGCCGCCGCCGCCCGAGGCCCCCCAAAGAT
  GGCGGACAAGGTGGTCCCACGGCAGGTGGCCCGGCTGGGCCGCACTGTGCGGCTGCAGTG
  CCCAGTGGAGGGGGACCCGCCGCCGCTGACCATGTGGACCAAGGATGGCCGCACCATCCA
  CAGCGGCTGGAGCCGCTTCCGCGTGCTGCCGCATGGGCTGAATGTGAATCATGTGGAGCG
  GGAGGATGCCGGCGTGTACGTGTGCAAGGCCACCAACGGCTTCGGCAGCCTGAGCGTCAA
  CTACACCCTCGTCGTGCTGGATGACATTAGCCCATGGAAGGAGAGCCTGGGGCCCGACAG
  CTCCTCTGGGGGTCAAGAGGACCCCGCCAGCCAGCAGTGGGCACGACCGCGCTTACACAG
  CCCTCCAGATGAGGCGCCGGGTGATCGCACGGCCCGTGGGTAGCTNCGTGNCGCTCAAGT
  GCGTGGCCAGCGGGCACCCTCGGCCCGACATCACGTGGATGAATGACGACAAGCCCTGAC
  CCGCCCATAGTCCGCTGATGCCAAGAAGAATAAT
  
• Restriction Sites: Please inquire
• ACCN: NM_021923
• ORF Size: 1515 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021923.3, NP_068742.2
• RefSeq Size: 3105
• RefSeq ORF: 1515
• Locus ID: 53834
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) has an alternate 5' UTR, and encodes the same isoform, as compared to variant 1.