VR1 (TRPV1) (NM_018727) Human Untagged Clone

CAT#: SC123895

TRPV1 (untagged)-Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPV1
• Synonyms: VR1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_018727 edited
  ATGAAGAAATGGAGCAGCACAGACTTGGGGGCAGCTGCGGACCCACTCCAAAAGGACACC
  TGCCCAGACCCCCTGGATGGAGACCCTAACTCCAGGCCACCTCCAGCCAAGCCCCAGCTC
  TCCACGGCCAAGAGCCGCACCCGGCTCTTTGGGAAGGGTGACTCGGAGGAGGCTTTCCCA
  GTGGATTGCCCTCACGAGGAAGGTGAGCTGGACTCCTGCCCGACCATCACAGTCAGCCCT
  GTTATCACCATCCAGAGGCCAGGAGACGGCCCCACCGGTGCCAGGCTGCTGTCCCAGGAC
  TCTGTCGCCGCCAGCACCGAGAAGACCCTCAGGCTCTATGATCGCAGGAGTATCTTTGAA
  GCCGTTGCTCAGAATAACTGCCAGGATCTGGAGAGCCTGCTGCTCTTCCTGCAGAAGAGC
  AAGAAGCACCTCACAGACAACGAGTTCAAAGACCCTGAGACAGGGAAGACCTGTCTGCTG
  AAAGCCATGCTCAACCTGCACGACGGACAGAACACCACCATCCCCCTGCTCCTGGAGATC
  GCGCGGCAAACGGACAGCCTGAAGGAGCTTGTCAACGCCAGCTACACGGACAGCTACTAC
  AAGGGCCAGACAGCACTGCACATCGCCATCGAGAGACGCAACATGGCCCTGGTGACCCTC
  CTGGTGGAGAACGGAGCAGACGTCCAGGCTGCGGCCCATGGGGACTTCTTTAAGAAAACC
  AAAGGGCGGCCTGGATTCTACTTCGGTGAACTGCCCCTGTCCCTGGCCGCGTGCACCAAC
  CAGCTGGGCATCGTGAAGTTCCTGCTGCAGAACTCCTGGCAGACGGCCGACATCAGCGCC
  AGGGACTCGGTGGGCAACACGGTGCTGCACGCCCTGGTGGAGGTGGCCGACAACACGGCC
  GACAACACGAAGTTTGTGACGAGCATGTACAATGAGATTCTGATGCTGGGGGCCAAACTG
  CACCCGACGCTGAAGCTGGAGGAGCTCACCAACAAGAAGGGAATGACGCCGCTGGCTCTG
  GCAGCTGGGACCGGGAAGATCGGGGTCTTGGCCTATATTCTCCAGCGGGAGATCCAGGAG
  CCCGAGTGCAGGCACCTGTCCAGGAAGTTCACCGAGTGGGCCTACGGGCCCGTGCACTCC
  TCGCTGTACGACCTGTCCTGCATCGACACCTGCGAGAAGAACTCGGTGCTGGAGGTGATC
  GCCTACAGCAGCAGCGAGACCCCTAATCGCCACGACATGCTCTTGGTGGAGCCGCTGAAC
  CGACTCCTGCAGGACAAGTGGGACAGATTCGTCAAGCGCATCTTCTACTTCAACTTCCTG
  GTCTACTGCCTGTACATGATCATCTTCACCATGGCTGCCTACTACAGGCCCGTGGATGGC
  TTGCCTCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTACTGGAGAGATCCTG
  TCTGTGTTAGGAGGAGTCTACTTCTTTTTCCGAGGGATTCAGTATTTCCTGCAGAGGCGG
  CCGTCGATGAAGACCCTGTTTGTGGACAGCTACAGTGAGATGCTTTTCTTTCTGCAGTCA
  CTGTTCATGCTGGCCACCGTGGTGCTGTACTTCAGCCACCTCAAGGAGTATGTGGCTTCC
  ATGGTATTCTCCCTGGCCTTGGGCTGGACCAACATGCTCTACTACACCCGCGGTTTCCAG
  CAGATGGGCATCTATGCCGTCATGATAGAGAAGATGATCCTGAGAGACCTGTGCCGTTTC
  ATGTTTGTCTACGTCGTCTTCTTGTTCGGGTTTTCCACAGCGGTGGTGACGCTGATTGAA
  GACGGGAAGAATGACTCCCTGCCGTCTGAGTCCACGTCGCACAGGTGGCGGGGGCCTGCC
  TGCAGGCCCCCCGATAGCTCCTACAACAGCCTGTACTCCACCTGCCTGGAGCTGTTCAAG
  TTCACCATCGGCATGGGCGACCTGGAGTTCACTGAGAACTATGACTTCAAGGCTGTCTTC
  ATCATCCTGCTGCTGGCCTATGTAATTCTCACCTACATCCTCCTGCTCAACATGCTCATC
  GCCCTCATGGGTGAGACTGTCAACAAGATCGCACAGGAGAGCAAGAACATCTGGAAGCTG
  CAGAGAGCCATCACCATCCTGGACACGGAGAAGAGCTTCCTTAAGTGCATGAGGAAGGCC
  TTCCGCTCAGGCAAGCTGCTGCAGGTGGGGTACACACCTGATGGCAAGGACGACTACCGG
  TGGTGCTTCAGGGTGGACGAGGTGAACTGGACCACCTGGAACACCAACGTGGGCATCATC
  AACGAAGACCCGGGCAACTGTGAGGGCGTCAAGCGCACCCTGAGCTTCTCCCTGCGGTCA
  AGCAGAGTTTCAGGCAGACACTGGAAGAACTTTGCCCTGGTCCCCCTTTTAAGAGAGGCA
  AGTGCTCGAGATAGGCAGTCTGCTCAGCCCGAGGAAGTTTATCTGCGACAGTTTTCAGGG
  TCTCTGAAGCCAGAGGACGCTGAGGTCTTCAAGAGTCCTGCCGCTTCCGGGGAGAAGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018727 unedited
  AGGGGNNATGGGNNNTNNNNTTGAGTCAGATTTTGTAATACGACTACTATAGGGCGGCCG
  CGAATTCGGCACGAGAGACACCAGAAAGTCTGGTGGCTTTGGTCCCAAGTGGGAAAAGAG
  AACTGCCCCATGCCCAGCTTGTGATTATCGTTTTTGGAGACCTGAAGCCCACACTCGGGT
  CGTATGGACTTCTGGAAAAGTTCTTGTCTCCTGGACTGAACCATGTGACCGGAGGCCCCT
  TTCCTAGTCTCATCCTCCCCTGGCTGCAGATGCTTAGCTGGGCCAGGGATTGACCCAAGC
  GCGATGCAGCAGGCAGGCTCAGAAGACGATGCGGGGCTGTGTGCCGGCCTTCTTGCTGCA
  TGTACTCAGCCTCAGGAGAGCTTGCTGCACCCAGGCCGCCCAGGTCTTCACAGCACAACT
  GCCTGGAAGGCAGGTTGCGAGAAGGAGAGGCGGATGGCATGAGCAGCAAGGGGGACCGAT
  GCTGTGCAGCTCACACCACTCCAGAACCTGACAAGGCACCAGCAGGACCCCTTGCCAGGA
  GCATGTCTGTGCAGCAGTGTTTTTGCCCCTGCACATTCCAGAAGCCCTCATGGGAAGGGA
  TGCAGCCAGGCAGACTCCTGCCAGATGGGGCAGGTTGCACACTGNGCCACAGAGGATCCA
  GCAAGGATGAAGAAATGGAGCAGCACAGACTTGGGGGCAGCTGCGGACCCACTCCAAAAG
  GACACCTGCCCAGACCCCCTGGATGGAGACCCTAACTTCAGGCCACTTCCAGCCAGCCCC
  AGCTCTCCACGCCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018727 unedited
  AGGGGTGGNNTNNNTTGCCTGGATGGCACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGT
  CACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGA
  GTCGAGTTTTTTTTTTTTTTTTTTATGTATACATATCTGTTTATTTGAGGATGCCAGTAT
  GGATGGAGTGGAAGCATGTGCCATTGCGGAGAAACAGGACTGGGGTTCCTAGAAATGGAA
  GATCTTTCAAACATTCTTACCAGGTACCTTTGGGATGTGGTTCTGTAGTTTTAACCTGCA
  CAGCAATTGAGCTGATCTTCTGGAGACTGTGATTGATCGTAAGGAAGGATGAAGAAAGCA
  CTGCTGCAACAGCTTGATTCTGCCAGAGCTGGGAGTGGGACAGCCTCCCCCATCTTCTCC
  AGGGAGGAAACACCAACACCCCCAAACCACCCGGGCAGGTAAGAGGAGCAAGCACGGCAC
  AGAGAGGAAGGGCCTCTGCATTTTCCATCAAAGGAAGAGTTTGTTCCCAAAGGTGTTTTC
  CTGGGCTTCATTTACTTTTGCTCCTAATAATATAAAATCAAAGAAGGCCGAGCGCAGCGG
  CTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAAG
  AGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTATTAAAAATACAAAAATT
  AGCCGGGCGTGGTAGTGCTCACCTGTAATCCAAGCTACTTGGGAGACTGAAGCAGAAGAA
  TCGCTTG
  
• Restriction Sites: Please inquire
• ACCN: NM_018727
• Insert Size: 5000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_018727.4, NP_061197.4
• RefSeq Size: 4046 bp
• RefSeq ORF: 2520 bp
• Locus ID: 7442
• Cytogenetics: 17p13.2
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: 'Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) contains a different segment in the 5' UTR, compared to variant 3. Variants 1-4 all encode the same protein.