CYP26A1 (NM_000783) Human Untagged Clone

CAT#: SC123897

CYP26A1 (untagged)-Human cytochrome P450, family 26, subfamily A, polypeptide 1 (CYP26A1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP26A1
• Synonyms: CP26; CYP26; P450RAI; P450RAI1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000783 edited
  GTCGCGGCGCGCCATGGGGCTCCCGGCGCTGCTGGCCAGTGCGCTCTGCACCTTCGTGCT
  GCCGCTGCTGCTCTTCCTGGCTGCGATCAAGCTCTGGGACCTGTACTGCGTGAGCGGCCG
  CGACCGCAGTTGTGCCCTCCCATTGCCCCCCGGGACTATGGGCTTCCCCTTCTTTGGGGA
  AACCTTGCAGATGGTACTGCAGCGGAGGAAGTTCCTGCAGATGAAGCGCAGGAAATACGG
  CTTCATCTACAAGACGCATCTGTTCGGGCGGCCCACCGTACGGGTGATGGGCGCGGACAA
  TGTGCGGCGCATCTTGCTCGGAGAGCACCGGCTGGTGTCGGTCCACTGGCCAGCGTCGGT
  GCGCACCATTCTGGGATCTGGCTGCCTCTCTAACCTGCACGACTCCTCGCACAAGCAGCG
  CAAGAAGGTGATTATGCGGGCCTTCAGCCGCGAGGCACTCGAATGCTACGTGCCGGTGAT
  CACCGAGGAAGTGGGCAGCAGCCTGGAGCAGTGGCTGAGCTGCGGCGAGCGCGGCCTCCT
  GGTCTACCCCGAGGTGAAGCGCCTCATGTTCCGAATCGCCATGCGCATCCTACTGGGCTG
  CGAACCCCAACTGGCGGGCGACGGGGACTCCGAGCAGCAGCTTGTGGAGGCCTTCGAGGA
  AATGACCCGCAATCTCTTCTCGCTGCCCATCGACGTGCCCTTCAGCGGGCTGTACCGGGG
  CATGAAGGCGCGGAACCTCATTCACGCGCGCATCGAGCAGAACATTCGCGCCAAGATCTG
  CGGGCTGCGGGCATCCGAGGCGGGCCAGGGCTGCAAAGACGCGCTGCAGCTGTTGATCGA
  GCACTCGTGGGAGAGGGGAGAGCGGCTGGACATGCAGGCACTAAAGCAATCTTCAACCGA
  ACTCCTCTTTGGAGGACACGAAACCACGGCCAGTGCAGCCACATCTCTGATCACTTACCT
  GGGGCTCTACCCACATGTTCTCCAGAAAGTGCGAGAAGAGCTGAAGAGTAAGGGTTTACT
  TTGCAAGAGCAATCAAGACAACAAGTTGGACATGGAAATTTTGGAACAACTTAAATACAT
  CGGGTGTGTTATTAAGGAGACCCTTCGACTGAATCCCCCAGTTCCAGGAGGGTTTCGGGT
  TGCTCTGAAGACTTTTGAATTAAATGGATACCAGATTCCCAAGGGCTGGAATGTTATCTA
  CAGTATCTGTGATACTCATGATGTGGCAGAGATCTTCACCAACAAGGAAGAATTTAATCC
  TGACCGATTCATGCTGCCTCACCCAGAGGATGCATCCAGGTTCAGCTTCATTCCATTTGG
  AGGAGGCCTTAGGAGCTGTGTAGGCAAAGAATTTGCAAAAATTCTTCTCAAAATATTTAC
  AGTGGAGCTGGCCAGGCATTGTGACTGGCAGCTTCTAAATGGACCTCCTACAATGAAAAC
  CAGTCCCACCGTGTATCCTGTGGACAATCTCCCTGCAAGATTCACCCATTTCCATGGGGA
  AATCTGATGAGCTTGAATGTTCAAACCTGAGACTTATTGGAAGTGTACATATGAGTTTTT
  AAGGAGTGTTGTGTTGACTTTATATTTAATTTCTAAATGTATATTATAATATTTATGTGT
  TTTGACTATACTACCACAATCTTTAAATATTAAAATAATGAATTTGTATCATTTCCAAAT
  AAAGTAAAATTTGAAGGTAAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCG
  CGGTCATAGCTGTTTCCTGAACAGATCCCG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000783 unedited
  AGTCGGAATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGGCAGGTG
  GCGCGGGAGGTCGCGGCGCGCCATGGGGCTCCCGGCGCTGCTGGCCAGTGCGCTCTGCAC
  CTTCGTGCTGCCGCTGCTGCTCTTCCTGGCTGCGATCAAGCTCTGGGACCTGTACTGCGT
  GAGCGGCCGCGACCGCAGTTGTGCCCTCCCATTGCCCCCCGGGACTATGGGCTTCCCCTT
  CTTTGGGGAAACCTTGCAGATGGTACTGCAGCGGAGGAAGTTCCTGCAGATGAAGCGCAG
  GAAATACGGCTTCATCTACAAGACGCATCTGTTCGGGCGGCCCACCGTACGGGTGATGGG
  CGCGGACAATGTGCGGCGCATCTTGCTCGGAGAGCACCGGCTGGTGTCGGTCCACTGGCC
  AGCGTCGGTGCGCACCATTCTGGGATCTGGCTGCCTCTCTAACCTGCACGACTCCTCGCA
  CAAGCAGCGCAAGAAGGTGATTATGCGGGCCTTCAGCCGCGAGGCACTCGAATGCTACGT
  GCCGGTGATCACCGAGGAAGTGGGCAGCAGCCTGGAGCAGTGGCTGAGCTGCGGCGAGCG
  CGGCCTCCTGGTCTACCCCGAGGTGAAGCGCCTCATGTTCCGAATCGCCATGCGCATCCT
  ACTGGGCTGCGAACCCCAACTGGCGGGCGACGGGGACTCCGAGCAGCAGCTTGTGGAGGC
  CTTCGAGGAATGACCCGCAATCTCTTCTCGCTGCCCATCGACGTGCCCTTCANCGGGCTG
  TACCGGGGCATGAAAGCGCGGAACCTCATTCACGCGCGCATCGAGCAGAACATCCCGCCC
  AGATCTGCGGGCTGCGGGCATCCGAGGCGGGCCAGGGCTGCAAAAACCCGCTGCAGCTGT
  TGATCAACCACTCCTGGGAGAGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000783 unedited
  AGGGGNNAGGNNNNTNNNNATTGTCTTGCCTGTTTGTGCGAGGAGTCGTGCAGGTTAGAG
  AGGCAGCCAGATCCCAGAATGGTGCGCACCGACGCTGGCCAGTGGACCGACACCAGCCGG
  TGCTCTCCGAGCAAGATGCGCCGCACATTGTCCGCGCCCATCACCCGTACGGTGGGCCGC
  CCGAACAGATGCGTCTTGTAGATGAAGCCGTATTTCCTGCGCTTCATCTGCAGGAACTTC
  CTCCGCTGCAGTACCATCTGCAAGGTTTCCCCAAAGAAGGGGAAGCCCATAGTCCCGGGG
  GGCAATGGGAGGGCACAACTGCGGTCGCGGCCGCTCACGCAGTACAGGTCCCAGAGCTTG
  ATCGCAGCCAGGAAGAGCAGCAGCGGCAGCACGAAGGTGCAGAGCGCACTGGCCAGCAGC
  GCCGGGAGCCCCATGGCGCGCCGCGACCTCCCGCGCCACCTGCCCCCTCGTGCCGAATTC
  GCGGCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCTGC
  TTATATAGACCTCCCACCGTACACGCCTACCGCCCATTTGCGTCAACGGGGCGGNGTTAT
  TACGACATTTTGGAAAGTCCCGTTGATTTTGGTGCCAAAACAAACTCCCATTGACGTCAA
  TGGNGTGGAGACTTGNAAATCCCCGTGAGTCANACCGCTATCCACGCCCATTGGTGTACT
  GCCAAAACCGCATCACCATGGTAATAGCGATGACTAATACGTAGATGTACTGCCAAGTAG
  GAAAGTCCCGTAGGGTCAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000783
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000783.2, NP_000774.2
• RefSeq Size: 2099 bp
• RefSeq ORF: 1494 bp
• Locus ID: 1592
• Cytogenetics: 10q23.33
• Domains: p450
• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Retinol metabolism
• Gene Summary: 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longer protein (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.