MMP3 (NM_002422) Human Untagged Clone

CAT#: SC123913

MMP3 (untagged)-Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMP3
• Synonyms: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123913 sequence for NM_002422 edited (data generated by NextGen Sequencing)
  ATGAAGAGTCTTCCAATCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTG
  GATGGAGCTGCAAGGGGTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAAC
  TACTACGACCTCGAAAAAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTT
  GTTAAAAAAATCCGAGAAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGAC
  TCCGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTC
  AGAACCTTTCCTGGCATCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAAT
  TATACACCAGATTTGCCAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTC
  TGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATG
  ATCTCTTTTGCAGTTAGAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTT
  TTGGCCCATGCCTATGCCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGAT
  GAACAATGGACAAAGGATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATT
  GGCCACTCCCTGGGTCTCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTAT
  CACTCACTCACAGACCTGACTCGGTTCCGCCTGTCTCAAGATGATATAAATGGCATTCAG
  TCCCTCTATGGACCTCCCCCTGACTCCCCTGAGACCCCCCTGGTACCCACGGAACCTGTC
  CCTCCAGAACCTGGGACGCCAGCCAACTGTGATCCTGCTTTGTCCTTTGATGCTGTCAGC
  ACTCTGAGGGGAGAAATCCTGATCTTTAAAGACAGGCACTTTTGGCGCAAATCCCTCAGG
  AAGCTTGAACCTGAATTGCATTTGATCTCTTCATTTTGGCCATCTCTTCCTTCAGGCGTG
  GATGCCGCATATGAAGTTACTAGCAAGGACCTCGTTTTCATTTTTAAAGGAAATCAATTC
  TGGGCCATCAGAGGAAATGAGGTACGAGCTGGATACCCAAGAGGCATCCACACCCTAGGT
  TTCCCTCCAACCGTGAGGAAAATCGATGCAGCCATTTCTGATAAGGAAAAGAACAAAACA
  TATTTCTTTGTAGAGGACAAATACTGGAGATTTGATGAGAAGAGAAATTCCATGGAGCCA
  GGCTTTCCCAAGCAAATAGCTGAAGACTTTCCAGGGATTGACTCAAAGATTGATGCTGTT
  TTTGAAGAATTTGGGTTCTTTTATTTCTTTACTGGATCTTCACAGTTGGAGTTTGACCCA
  AATGCAAAGAAAGTGACACACACTTTGAAGAGTAACAGCTGGCTTAATTGTTGA
  
  Clone variation with respect to NM_002422.3
  133 a=>g;288 t=>c;1086 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002422 unedited
  NGGTCAGTCAAATATTTGTAATAGACTCACTATAGGCGGCCGCGNAATTCGCACCAGNAC
  AGCAAGGCATAGAGACAACATAGAGCTAAGTAAAGCCAGTGGAAATGAAGAGTCTTCCAA
  TCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTGGATGGAGCTGCAAGGG
  GTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAACTACTACGACCTCGAAA
  AAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTTGTTAAAAAAATCCGAG
  AAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGACTCCGACACTCTGGAGG
  TGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTCAGAACCTTTCCTGGCA
  TCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAATTATACACCAGATTTGC
  CAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTC
  CACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATGATCTCTTTTGCAGTTA
  GAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTTTTGGCCCATGCCTATG
  CCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGATGAACAATGGACAAAGG
  ATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATTGGCCACTCCCTGGGTC
  TCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTATCACTCACTCACAGACC
  TGACTCGGGTCCGCCTGTCTCAAGAGATATAAAGGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002422 unedited
  TTTCCGGCCAGGAGTTGCACAGAGGAGCCGTCACAGGGATGCCACCCGGGATCTGTTCAG
  GAAACAGCTATGACCTGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAA
  TAACTGACAAATCGTCTTTATTAAATAAGCAAATAGTCTACACAGATACAGTCACTTGTC
  TGTTGCACACGAGTGCTTCCCCTTCTCTTGGGAAAGATCACTCTATGTGACAAGGTGCAA
  GCTAAGCAGCAGCCCATTTGAATGCCCTGTAATAACATAAAAATGACCGGCAAGATACAG
  ATTCACGCTCAAGTTCCCTTGAGTGTGACTCGAGTCACAGCACAGGCAGGAGAAAACGAA
  CATTTCAATTCACAGAGACTTAGGTGAAGAATTATTAGCTTCATTTAAAGTGCCCATATT
  GTGCCTTCTACATATCTCTTTCAACAATTAAGCCAGCTGTTACTCTTCAAAGTGTGTGTC
  ACTTTCTTTGCATTTGGGTCAAACTCCAACTGTGAAGATCCAGTAAAGAAATAAAAGAAC
  CCAAATTCTTCAAAAACAGCATCAATCTTTGAGTCAATCCCTGGAAAGTCTTCAGCTATT
  TGCTTGGGAAAGCCTGGCTCCATGGAATTTCTCTTCTCATCAAATCTCCAGTATTTGTCC
  TCTACAAAGAAATATGTTTTGTTCTTTTCCTTATCAGAAATGGCTGCATCGATTTTCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_002422
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002422.3, NP_002413.1
• RefSeq Size: 1828 bp
• RefSeq ORF: 1434 bp
• Locus ID: 4314
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome, Protease
• Gene Summary: 'Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]'