KCNMB3 (NM_171828) Human Untagged Clone

CAT#: SC123922

KCNMB3 (untagged)-Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1


  "NM_171828" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KCNMB3
Synonyms BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC123922 sequence for NM_171828 edited (data generated by NextGen Sequencing)
ATGCAGCCCTTCAGCATCCCCGTGCAAATCACACTTCAGGGCAGCCGGAGGCGCCAGGGG
AGGACAGCCTTTCCTGCCTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCA
CTAGATGTGCACAAGAGGCTGCCATCCAGTACTGGAGAGGACCGAGCCGTGATGCTGGGG
TTTGCCATGATGGGCTTCTCAGTCCTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAG
CCTTTTATGCTCAGCATTCAGAGAGAAGAATCGACCTGCACTGCCATCCACACAGATATC
ATGGACGACTGGCTGGACTGTGCCTTCACCTGTGGTGTGCACTGCCACGGTCAGGGGAAG
TACCCGTGTCTTCAGGTGTTTGTGAACCTCAGCCATCCAGGTCAGAAAGCTCTCCTACAT
TATAATGAAGAGGCTGTCCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCCACCAA
GATAGAAATGATTTGCTCAACAATGCTCTGGACATAAAAGAATTCTTCGATCACAAAAAT
GGAACCCCCTTTTCATGCTTCTACAGTCCAGCCAGCCAATCTGAAGATGTCATTCTTATA
AAAAAGTATGACCAAATGGCTATCTTCCACTGTTTATTTTGGCCTTCACTGACTCTGCTA
GGTGGTGCCCTGATTGTTGGCATGGTGAGATTAACACAACACCTGTCCTTACTGTGTGAA
AAATATAGCACTGTAGTCAGAGATGAGGTAGGTGGAAAAGTACCTTATATAGAACAGCAT
CAGTTCAAACTGTGCATTATGAGGAGGAGCAAAGGAAGAGCAGAGAAATCTTAA

Clone variation with respect to NM_171828.1
151 g=>a;503 g=>a
>OriGene 5' read for NM_171828 unedited
CCACTCACTATATGGCGGCCGCGCAGCAGACCACGCAGGTCCTTCTTGATCATCTAGAAC
TGACCGCTCCGCCTTGCCAGGAGTCTGCAGAACCACGTGGCTAGCCTGCCTGAAGTTCTC
ACCTCTCCAGGAAGGCGGGGGGCTTCTAATGGCTGCAGCTGCGCTGGGGGCTGGGGGCTC
CCGCTGGGACTCCACTTCCGTGGATGTCTAAGCTTCACCTTTCTTGCGCCCGCAGGGGCA
TGACTCAGGTGAAAGGGAGCCATTTTCTCAGACCCCTGGCCTCATGCAGCCCTTCAGCAT
CCCCGTGCAAATCACACTTCAGGGCAGCCGGAGGCGCCAGGGGAGGACAGCCTTTCCTGC
CTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCACTAGATGTGCACAAGAG
GCTGCCATCCAGTACTGGAGAGGACCGAGCCGTGATGCTGGGGTTTGCCATGATGGGCTT
CTCAGTCCTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAGCCTTTTATGCTCAGCAT
TCAGAGAGAAGAATCGACCTGCACTGCCATCCACACAGATATCATGGACGACTGGCTGGA
CTGTGCCTTCACCTGTGGTGTGCACTGCCACGGTCAGGGGAAGTACCCGTGTCTTCAGGT
GTTTGTGAACCTCAGCCATCCAGGTCAGAAAGCTCTCCTACATTATAATGAAGAGGCTGT
CCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCN
>OriGene 3' read for NM_171828 unedited
TCCGGGCCAGGATAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG
AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTGGTTTTTTTTTTTTTT
TTTTAAATTTTTTCCCACATGAAAATATGATACTTTAATTATTACCTTTTACATTGTTAG
TTTGCAGACAGGCATAATTAGGTCCTCAGTTGCAGAAATCACAGACATCTGAAGGCCAGC
ACTTTAATTTGGCCACCGTCTTAAGATTTCTCTGCTCTTCCTTTGCTCCTCCTCATAATG
CACAGTTTGAACTGATGCTGTTCTATATAAGGTACTTTTCCACCTACCTCATCTCTGACT
ACAGTGCTATATTTTTCACACAGTAAGGACAGGTGTTGTGTTAATCTCACCATGCCAACA
ATCAGGGCACCACCTAGCAGAGTCAGTGAAGGCCAAAATAAACAGTGGAAGATAGCCATT
TGGTCATACTTTTTTATAAGAATGACATCTTCAGATTGGCTGGCTGGACTGTAGAAGCAT
GAAAAGGGGGTTCCATTTTTGTGATCGAAGAATTCTTTTATGTCCAGAGCATTGTTGAGC
AAATCATTTCTATCTTGGTGGCACTTAGGTGTGTAAAAGCACTTGGGATTTATCTGGACA
GCCTCTTCATTATAATGTAGGAGAGCTTTCTGACCTGGATGGCTGAGGTTCACAAACACC
TGAAGACACGGGTACTTCCCCTGACCGTGGCAGTGCAC
Restriction Sites NotI-NotI     
ACCN NM_171828
ORF Size 834 bp
Insert Size 6200
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_171828.1, NP_741979.1
RefSeq Size 1272
RefSeq ORF 834
Locus ID 27094
Protein Families Druggable Genome, Ion Channels: Other, Transmembrane
Protein Pathways Vascular smooth muscle contraction
Gene Summary MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]
Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region, and uses an alternate translational start codon, compared to variant 4. The resulting isoform (a) has a distinct N-terminus and is shorter than isoform d. CCDS Note: This CCDS representation is supported by accession AF204159.1 and data in PMID:10766764.

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