KCNMB3 (NM_171829) Human Untagged Clone

CAT#: SC123933

KCNMB3 (untagged)-Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNMB3
• Synonyms: BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_171829, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACAGCCTTTCCTGCCTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCACTAGATGTGC
  ACAAGAGGCTGCCATCCAGTGCTGGAGAGGACCGAGCCGTGATGCTGGGGTTTGCCATGATGGGCTTCTC
  AGTCCTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAGCCTTTTATGCTCAGCATTCAGAGAGAAGAA
  TCGACCTGCACTGCCATCCACACAGATATCATGGACGACTGGCTGGACTGTGCCTTCACCTGTGGTGTGC
  ACTGCCACGGTCAGGGGAAGTACCCGTGTCTTCAGGTGTTTGTGAACCTCAGCCATCCAGGTCAGAAAGC
  TCTCCTACATTATAATGAAGAGGCTGTCCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCCACCAA
  GATAGAAATGATTTGCTCAACAGTGCTCTGGACATAAAAGAATTCTTCGATCACAAAAATGGAACCCCCT
  TTTCATGCTTCTACAGTCCAGCCAGCCAATCTGAAGATGTCATTCTTATAAAAAAGTATGACCAAATGGC
  TATCTTCCACTGTTTATTTTGGCCTTCACTGACTCTGCTAGGTGGTGCCCTGATTGTTGGCATGGTGAGA
  TTAACACAACACCTGTCCTTACTGTGTGAAAAATATAGCACTGTAGTCAGAGATGAGGTAGGTGGAAAAG
  TACCTTATATAGAACAGCATCAGTTCAAACTGTGCATTATGAGGAGGAGCAAAGGAAGAGCAGAGAAATC
  TTAA
  
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_171829 unedited
  CCGTCTTAAGATTTCTCTGCTCTTCCTTTGCTCCTCCTCATAATGCACAGTTTGAACTGA
  TGCTGTTCTATATAAGGTACTTTTCCACCTACCTCATCTCTGACTACAGTGCTATATTTT
  TCACACAGTAAGGACAGGTGTTGTGTTAATCTCACCATGCCAACAATCAGGGCACCACCT
  AGCAGAGTCAGTGAAGGCCAAAATAAACAGTGGAAGATAGCCATTTGGTCATACTTTTTT
  ATAAGAATGACATCTTCAGATTGGCTGGCTGGACTGTAGAAGCATGAAAAGGGGGTTCCA
  TTTTTGTGATCGAAGAATTCTTTTATGTCCAGAGCACTGTTGAGCAAATCATTTCTATCT
  TGGTGGCACTTAGGTGTGTAAAAGCACTTGGGATTTATCTGGACAGCCTCTTCATTATAA
  TGTAGGAGAGCTTTCTGACCTGGATGGCTGAGGTTCACAAACACCTGAAGACACGGGTAC
  TTCCCCTGACCGTGGCAGTGCACACCACAGGTGAAGGCACAGTCCAGCCAGTCGTCCATG
  ATATCTGTGTGGATGGCAGTGCAGGTCGATTCTTCTCTCTGAATGCTGAGCATAAAAGGC
  TTTAGAATGGTTGTTCCGAGCAAGAAGAACATTAGGACTGAGAAGCCCATCATGGCAAAC
  CCCAGCATCACGGCTCGGTCCTCTCCAGCACTGGATGGCAGCCTCTTGTGCACATCTAGT
  GGGTCTCCATCACTGTAGTCTGTCTCTCTCTTCTTCCCTGAGGCANGAAAGGCTGTCATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_171829
• ORF Size: 774 bp
• Insert Size: 3700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_171829.1, NP_741980.1
• RefSeq Size: 1709
• RefSeq ORF: 774
• Locus ID: 27094
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Vascular smooth muscle contraction
• Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate translational start codon, compared to variant 4. The resulting isoform (b) has a distinct N-terminus and is shorter than isoform d.