Kv beta 2 (KCNAB2) (NM_172130) Human Untagged Clone

CAT#: SC123941

KCNAB2 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 2 (KCNAB2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNAB2
• Synonyms: AKR6A5; HKvbeta2; HKvbeta2.1; HKvbeta2.2; KCNA2B; KV-BETA-2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_172130 edited
  ATGTATCCAGAATCAACGACGGGCTCCCCGGCTCGGCTCTCGCTGCGGCAGACGGGCTCC
  CCCGGGATGATCTACAGGAACCTGGGCAAGTCTGGCCTGCGGGTCTCCTGCCTGGGACTT
  GGAACATGGGTGACCTTCGGAGGCCAGATCACCGATGAGATGGCAGAGCAGCTCATGACC
  TTGGCCTATGATAATGGCATCAACCTCTTCGATACAGCAGAAGTCTACGCAGCCGGCAAG
  GCTGAAGTGGTACTGGGAAACATCATTAAGAAGAAAGGATGGAGGCGGTCCAGCCTCGTC
  ATCACCACCAAGATCTTCTGGGGCGGAAAGGCGGAGACGGAGCGGGGCCTGTCCAGGAAG
  CACATAATCGAAGGTCTGAAAGCTTCCCTGGAGCGACTGCAGCTGGAGTACGTGGATGTG
  GTGTTTGCCAACCGCCCGGACCCCAACACCCCGATGGAAGAGACCGTCCGCGCCATGACC
  CACGTCATCAACCAGGGGATGGCCATGTACTGGGGCACGTCACGCTGGAGCTCCATGGAG
  ATCATGGAGGCCTACTCCGTGGCCCGGCAGTTCAACCTGACCCCGCCCATCTGCGAGCAG
  GCTGAGTACCACATGTTCCAGCGTGAGAAAGTGGAGGTGCAGCTGCCGGAGCTGTTCCAC
  AAGATAGGAGTGGGCGCCATGACCTGGTCCCCTCTGGCCTGTGGCATTGTTTCTGGCAAG
  TACGACAGTGGCATCCCACCCTACTCAAGAGCCTCCTTGAAGGGCTACCAGTGGCTGAAG
  GACAAGATCCTCAGTGAGGAGGGCCGGCGCCAGCAAGCCAAGCTGAAGGAGCTGCAGGCC
  ATCGCCGAGCGCCTGGGCTGCACCCTGCCCCAGCTGGCCATAGCCTGGTGCCTGAGGAAT
  GAGGGAGTCAGCTCCGTGCTCCTGGGGGCCTCCAATGCGGACCAGCTCATGGAGAACATT
  GGGGCAATACAGGTCCTTCCGAAACTGTCATCTTCCATTATCCACGAGATTGATAGTATT
  TTGGGCAATAAACCCTACAGCAAAAAGGACTACAGATCCTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172130 unedited
  AAATCACAATTCGCACCAGGCTAAAGTCTTCGGGGCAGGGCGCGGAAGCAAAATCCCGCG
  CGGGGCACATGATCCGGAGCTGGAGCCCCCAGAATTTTCCCACTGTAAAAAACCGAGCAA
  GTCTGGATAAGTGAGGCTGGCTCCATGTATCCAGAATCAACGACAGGCTCCCCGGCTCGC
  TCNTCCTGCGGCAGACGGGCTCCCTTGGGATGATCTACAGGAACCTGGGCAAGTCTGGCC
  TGCGGGTCTCCTGCCTGGGACTTGGAACATGGGTGACCTTCGGAGGCCAGATCACCGATG
  AGATGGCAGAGCAGCTCATGACCTTGGCCTATGATAATGGCATCAACCTCTTCGATACAG
  CAGAAGTCTACGCAGCCGGCAAGGCTGAAGTGGTACTGGGAAACATCATTAAGAAGAAAG
  GATGGAGGCGGTCCAGCCTCGTCATCACCACCAAGATCTTCTGGGGCGGAAAGGCGGAGA
  CGGAGCGGGGCCTGTCCAGGAAGCACATAATCGAAGGTCTGAAAGCTTCCCTGGAGCGAC
  TGCAGCTGGAGTACGTGGATGTGGTGTTTGCCAACCGCCCGGACCCCAACACCCCGATGG
  AAGAGACCGTCCGCGCCATGACCCACGTCATCAACCAGGGGATGGCCATGTACTGGGGCA
  CGTCACGCTGGAGCTCCATGGAGATCATGGAGGCCTACTTCCTGGCCCGGCAGGTTCAAC
  CTGACCCCGCCCATCTGCGAGCAGGCTTGATACCACATGTTCCCACGTGAAAAAATGTGA
  GTGCCACTGCCCGAGCTGTTCCCCAGATAGGATGGGGCCCATGACCCGTTCCCCTTTGGC
  CCGTGGCATTGTTTTTTGGAAAGTACAAACAGGGGCTCCCCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_172130
• ORF Size: 1062 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_172130.1, NP_742128.1
• RefSeq Size: 3129
• RefSeq ORF: 1062
• Locus ID: 8514
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2), also known as HKvbeta2.2, lacks an in-frame exon in the coding region, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.