Pepsinogen II (PGC) (NM_002630) Human Untagged Clone

CAT#: SC123989

PGC (untagged)-Human progastricsin (pepsinogen C) (PGC), transcript variant 1


  "NM_002630" in other vectors (4)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PGC
Synonyms PEPC; PGII
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC123989 sequence for NM_002630 edited (data generated by NextGen Sequencing)
ATGAAGTGGATGGTGGTGGTCTTGGTCTGCCTCCAGCTCTTGGAGGCAGCAGTGGTCAAA
GTGCCCCTGAAGAAATTTAAGTCTATCCGTGAGACCATGAAGGAGAAGGGCTTGCTGGGG
GAGTTCCTGAGGACCCACAAGTATGATCCTGCTTGGAAGTACCGCTTTGGTGACCTCAGC
GTGACCTACGAGCCCATGGCCTACATGGATGCTGCCTACTTTGGTGAGATCAGCATCGGG
ACTCCACCCCAGAACTTCCTGGTCCTTTTTGACACCGGCTCCTCCAACTTGTGGGTGCCC
TCTGTCTACTGCCAGAGCCAGGCCTGCACCAGTCACTCCCGCTTCAACCCCAGCGAGTCG
TCCACCTACTCCACCAATGGGCAGACCTTCTCCCTGCAGTATGGCAGTGGCAGCCTCACC
GGCTTCTTTGGCTATGACACCCTGACTGTCCAGAGCATCCAGGTCCCCAACCAGGAGTTC
GGCTTGAGTGAGAATGAGCCTGGTACCAACTTCGTCTATGCGCAGTTTGATGGCATCATG
GGCCTGGCCTACCCTGCTCTGTCCGTGGATGAGGCCACCACAGCTATGCAGGGCATGGTG
CAGGAGGGCGCCCTCACCAGCCCCGTCTTCAGCGTCTACCTCAGCAACCAGCAGGGCTCC
AGCGGGGGAGCGGTTGTCTTTGGGGGTGTGGATAGCAGCCTGTACACGGGGCAGATCTAC
TGGGCGCCTGTCACCCAGGAACTCTACTGGCAGATTGGCATTGAAGAGTTCCTCATCGGC
GGCCAGGCCTCCGGCTGGTGTTCTGAGGGTTGCCAGGCCATCGTGGACACAGGCACCTCT
CTGCTCACTGTGCCCCAGCAGTACATGAGTGCTCTTCTGCAGGCCACAGGGGCCCAGGAG
GATGAGTATGGACAGTTTCTCGTGAACTGTAACAGCATTCAGAATCTGCCCAGCTTGACC
TTCATCATCAATGGTGTGGAGTTCCCTCTGCCACCTTCCTCCTATATCCTCAGTAACAAC
GGCTACTGCACCGTGGGAGTCGAGCCCACCTACCTGTCCTCCCAGAACGGCCAGCCCCTG
TGGATCCTCGGGGATGTCTTCCTCAGGTCCTACTATTCCGTCTACGACTTGGGCAACAAC
AGAGTAGGCTTTGCCACTGCCGCCTAG

Clone variation with respect to NM_002630.3
>OriGene 5' read for NM_002630 unedited
CAGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGNAACTCAGAGC
TGCTCTTCCTCTGTGGCCAGTTGGGGACCAGCATCATGAAGTGGATGGTGGTGGTCTTGG
TCTGCCTCCAGCTCTTGGAGGCAGCAGTGGTCAAAGTGCCCCTGAAGAAATTTAAGTCTA
TCCGTGAGACCATGAAGGAGAAGGGCTTGCTGGGGGAGTTCCTGAGGACCCACAAGTATG
ATCCTGCTAGGAAGTACCGCTTTGGTGACCTCAGCGTGACCTACGAGCCCATGGCCTACA
TGGATGCTGCCTACTTTGGTGAGATCAGCATCGGGACTCCACCCCAGAACTTCCTGGTCC
TTTTTGACACCGGCTCCTCCAACTTGTGGGTGCCCTCTGTCTACTGCCAGAGCCAGGCCT
GCACCAGTCACTCCCGCTTCAACCCCGGCGAGTCGTCCACCTACTCCACCAATGGGCAGA
CCTTCTCCCTGCAGTATGGCAGTGGCAGCCTCACCGGCTTCTTTGGCTATGACACCCCGA
GCGGCCAAAACATCCAGGTCCCCAACCAGAATTTCGGCTTGATTGAAAATGAACCTGGTA
CCAATTTGTCTATGCGCAATTTGAGTGCATATGGGCCGTGGCTACACCTGTCTGGCCGGG
GAGAGGCCACCCAGCTTATACAGGGCATAGTGAACGGAGGCCCCCTAAACAAGCCCGGTT
TAGAGCTTTCATGAACAACCCACGAGGGCTCCCCCGGGGGGGCCGATAGGCTTGGGCGAG
TGGGTATACACCACTGTCACCGACCCCAATAAACGGAGCACATGTGTCAATACGTCTAGG
TTGGCGGAATGCGTGGAGAAGAAAAAGCGAGGAAGGGAGCGATAACCGGGTAGTGTTAAC
GAGCAATGATTCTACAGTTATGCTGCGAAGACAGCAAAGCCAGTAATCTGCGCCGAAGN
>OriGene 3' read for NM_002630 unedited
TGGGGAAGTGNNNTTTTGCATGCGTGTCACTTCCCGGCCAGGAGAGGCACTGNGGAGGGG
TCAAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGA
GTCGAGTTTTTTTTTTTTTTTTTTTAAAGAAGAACTATTTATTATTAGAGAAAGTCCAGA
GTCCAGAAAAAGAAGGCTGAATCCAGAGTGGAAAGACAGATACAATGCCCTAGGAGGGTG
CAGGGTCAAGAGGAAGAGGGGAGCCCACGTGTCGAGGCAGCAAGTCTAGGCGGCAGTGGC
AAAGCCTACTCTGTTGTTGCCCAAGTCGTAGACGGAATAGTAGGACCTGAGGAAGACATC
CCCGAGGATCCACAGGGGCTGGCCGTTCTGGGAGGACAGGTAGGTGGGCTCGACTCCCAC
GGTGCAGTAGCCGTTGTTACTGAGGATATAGGAGGAAGGTGGCAGAGGGAACTCCACACC
ATTGATGATGAAGGTCAAGCTGGGCAGATTCTGAATGCTGTTACAGTTCACGAGAAACTG
TCCATACTCATCCTCCTGGGCCCCTGTGGCCTGCAGAAGAGCACTCATGTACTGGCTGGG
CACAGTGAGCAAAAAGGTGCCTGTGTCCACGATGGCCTGGGCACCCTCAGAACACCAGCC
CGAGGCCTGCCCGCCGATGAAGAACCTCTCAATGCAAATCTTGCATTNAAGTTCCTGGTG
ACAGGGCCCAATAATACGTGCCGGGTCAGGCTGGTTTCCCACCCCCAAAGAAACCGGTTC
CCGGTTGGACCCTGCTGTTGCGT
Restriction Sites Please inquire     
ACCN NM_002630
Insert Size 1700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002630.1, NP_002621.1
RefSeq Size 1366 bp
RefSeq ORF 1167 bp
Locus ID 5225
Cytogenetics 6p21.1
Protein Families Protease, Secreted Protein
Gene Summary 'This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

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