Angiotensin Converting Enzyme 2 (ACE2) (NM_021804) Human Untagged Clone

CAT#: SC124099

ACE2 (untagged)-Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACE2
• Synonyms: ACEH
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_021804, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAAGCTCTTCCTGGCTCCTTCTCAGCCTTGTTGCTGTAACTGCTGCTCAGTCCACCATTGAGGAAC
  AGGCCAAGACATTTTTGGACAAGTTTAACCACGAAGCCGAAGACCTGTTCTATCAAAGTTCACTTGCTTC
  TTGGAATTATAACACCAATATTACTGAAGAGAATGTCCAAAACATGAATAATGCTGGGGACAAATGGTCT
  GCCTTTTTAAAGGAACAGTCCACACTTGCCCAAATGTATCCACTACAAGAAATTCAGAATCTCACAGTCA
  AGCTTCAGCTGCAGGCTCTTCAGCAAAATGGGTCTTCAGTGCTCTCAGAAGACAAGAGCAAACGGTTGAA
  CACAATTCTAAATACAATGAGCACCATCTACAGTACTGGAAAAGTTTGTAACCCAGATAATCCACAAGAA
  TGCTTATTACTTGAACCAGGTTTGAATGAAATAATGGCAAACAGTTTAGACTACAATGAGAGGCTCTGGG
  CTTGGGAAAGCTGGAGATCTGAGGTCGGCAAGCAGCTGAGGCCATTATATGAAGAGTATGTGGTCTTGAA
  AAATGAGATGGCAAGAGCAAATCATTATGAGGACTATGGGGATTATTGGAGAGGAGACTATGAAGTAAAT
  GGGGTAGATGGCTATGACTACAGCCGCGGCCAGTTGATTGAAGATGTGGAACATACCTTTGAAGAGATTA
  AACCATTATATGAACATCTTCATGCCTATGTGAGGGCAAAGTTGATGAATGCCTATCCTTCCTATATCAG
  TCCAATTGGATGCCTCCCTGCTCATTTGCTTGGTGATATGTGGGGTAGATTTTGGACAAATCTGTACTCT
  TTGACAGTTCCCTTTGGACAGAAACCAAACATAGATGTTACTGATGCAATGGTGGACCAGGCCTGGGATG
  CACAGAGAATATTCAAGGAGGCCGAGAAGTTCTTTGTATCTGTTGGTCTTCCTAATATGACTCAAGGATT
  CTGGGAAAATTCCATGCTAACGGACCCAGGAAATGTTCAGAAAGCAGTCTGCCATCCCACAGCTTGGGAC
  CTGGGGAAGGGCGACTTCAGGATCCTTATGTGCACAAAGGTGACAATGGACGACTTCCTGACAGCTCATC
  ATGAGATGGGGCATATCCAGTATGATATGGCATATGCTGCACAACCTTTTCTGCTAAGAAATGGAGCTAA
  TGAAGGATTCCATGAAGCTGTTGGGGAAATCATGTCACTTTCTGCAGCCACACCTAAGCATTTAAAATCC
  ATTGGTCTTCTGTCACCCGATTTTCAAGAAGACAATGAAACAGAAATAAACTTCCTGCTCAAACAAGCAC
  TCACGATTGTTGGGACTCTGCCATTTACTTACATGTTAGAGAAGTGGAGGTGGATGGTCTTTAAAGGGGA
  AATTCCCAAAGACCAGTGGATGAAAAAGTGGTGGGAGATGAAGCGAGAGATAGTTGGGGTGGTGGAACCT
  GTGCCCCATGATGAAACATACTGTGACCCCGCATCTCTGTTCCATGTTTCTAATGATTACTCATTCATTC
  GATATTACACAAGGACCCTTTACCAATTCCAGTTTCAAGAAGCACTTTGTCAAGCAGCTAAACATGAAGG
  CCCTCTGCACAAATGTGACATCTCAAACTCTACAGAAGCTGGACAGAAACTGTTCAATATGCTGAGGCTT
  GGAAAATCAGAACCCTGGACCCTAGCATTGGAAAATGTTGTAGGAGCAAAGAACATGAATGTAAGGCCAC
  TGCTCAACTACTTTGAGCCCTTATTTACCTGGCTGAAAGACCAGAACAAGAATTCTTTTGTGGGATGGAG
  TACCGACTGGAGTCCATATGCAGACCAAAGCATCAAAGTGAGGATAAGCCTAAAATCAGCTCTTGGAGAT
  AAAGCATATGAATGGAACGACAATGAAATGTACCTGTTCCGATCATCTGTTGCATATGCTATGAGGCAGT
  ACTTTTTAAAAGTAAAAAATCAGATGATTCTTTTTGGGGAGGAGGATGTGCGAGTGGCTAATTTGAAACC
  AAGAATCTCCTTTAATTTCTTTGTCACTGCACCTAAAAATGTGTCTGATATCATTCCTAGAACTGAAGTT
  GAAAAGGCCATCAGGATGTCCCGGAGCCGTATCAATGATGCTTTCCGTCTGAATGACAACAGCCTAGAGT
  TTCTGGGGATACAGCCAACACTTGGACCTCCTAACCAGCCCCCTGTTTCCATATGGCTGATTGTTTTTGG
  AGTTGTGATGGGAGTGATAGTGGTTGGCATTGTCATCCTGATCTTCACTGGGATCAGAGATCGGAAGAAG
  AAAAATAAAGCAAGAAGTGGAGAAAATCCTTATGCCTCCATCGATATTAGCAAAGGAGAAAATAATCCAG
  GATTCCAAAACACTGATGATGTTCAGACCTCCTTTTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021804 unedited
  AAAGTCAGTATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGAAAGGAA
  GAGGAAGTAACTTGTGGAATGTTGAGAAAGCGCCCAACCCAAGTTCAAAGGCTGATAAGA
  GAGAAAATCTCATGAGGAGGTTTTAGTCTAGGGAAAGTCATTCAGTGGATGTGATCTTGG
  CTCACAGGGGACGATGTCAAGCTCTTCCTGGCTCCTTCTCAGCCTTGTTGCTGTAACTGC
  TGCTCAGTCCACCATTGAGGAACAGGCCAAGACATTTTTGGACAAGTTTAACCACGAAGC
  CGAAGACCTGTTCTATCAAAGTTCACTTGCTTCTTGGAATTATAACACCAATATTACTGA
  AGAGAATGTCCAAAACATGAATAATGCTGGGGACAAATGGTCTGCCTTTTTAAAGGAACA
  GTCCACACTTGCCCAAATGTATCCACTACAAGAAATTCAGAATCTCACAGTCAAGCTTCA
  GCTGCAGGCTCTTCAGCAAAATGGGTCTTCAGTGCTCTCAGAAGACAAGAGCAAACGGTT
  GAACACAATTCTAAATACAATGAGCACCATCTACCGTACTGGAAAAGTTTGGTACCCCGA
  TAATCCACAAGAATGCTTATTACTTGAACCAGGTTTGAATGAAATAATGGCCAACATTTT
  ATACTACAATGAGAGGCTCTGGGCTTGGGAAAACTGGAGATCTGATGTCGGCAAGCACTG
  GAGCCCTTTTATAAAAAGATGTGGTCTTGAAAAAGAGAGGGCCGAGCCAAACTTTTTAGG
  GCCATGGGGATATTTGGGAGGGGCCATTCAAACAATGGGGGAATGGCTTATACTCGCCCC
  GCCCCTTTTTGAAAATGTGACCTCCCTTTGAGGAATAAACCCTTTTTTAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021804 unedited
  GGAGTGGCACTGGGGAGGCGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTA
  TGATTTTTGCCGCAATCTAGAGTNNNNGTGTTTTTTGGGTTTTTTGTGTGTAAATCTAGC
  ATTTATTGAGTGTCTGCTTCGTGCTCAACACTGCTCATACACTGTGAGCAAATACAAAAT
  ATTTAAGAGACTGGGTACCCACTTCATAGGGTGAACATACAGTTGGAATTTCCATTCACT
  CCATAGTTAGAGAACAGTAGAAATGAGTTTCTATCAAGCATGCTCTGGGAGTTCACGGAG
  GCCCCTGGCTCTAGTTTTGTGTTGTCAGGGAGATGTTGATCAAGCACCTTGGAAGTGAAA
  AAGCAATGTCCTCTACCTGTTCCCTGGATTCTTCTCTCTTTAGACCTGTCACCTTGAAGA
  AAGCATGATCGATTCCAAACATCACTGTAGGCAAATCACCATAGTACTTGAACTGAGTTA
  CTGTGAAGAAAGCATGTCATCCTTGACTATGGATTAAATGAAAGTGAGCTAATGCTTGCC
  CTTCTAAATCCTTGCAGCTACAACCATTTCCCAGGCCCTTGTCCTTACAACGTGATTCCA
  TCCCTTATTCCATACAGAGATCCAACACCTTGCTCCAATGATATATTCCTTGTTTTACAC
  TTCAGAAATTTCACACACATTTAGCGTTTAGATTATCCTTGAACCAGCTTGTGAAGACCC
  AATACACCACTTCGCTTAATATACTCTTATACAAAAATTCTTATTAAGAATCAGAAG
  
• Restriction Sites: Please inquire
• ACCN: NM_021804
• ORF Size: 2418 bp
• Insert Size: 3800
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_021804.1, NP_068576.1
• RefSeq Size: 3405
• RefSeq ORF: 2418
• Locus ID: 59272
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Renin-angiotensin system
• Gene Summary: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]