CHRNA6 (NM_004198) Human Untagged Clone

CAT#: SC124153

CHRNA6 (untagged)-Human cholinergic receptor, nicotinic, alpha 6 (CHRNA6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHRNA6
• Synonyms: CHNRA6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124153 sequence for NM_004198 edited (data generated by NextGen Sequencing)
  ATGCTGACCAGCAAGGGGCAGGGATTCCTTCATGGGGGCTTGTGTCTCTGGCTGTGTGTG
  TTCACACCTTTCTTTAAAGGCTGTGTGGGCTGTGCAACTGAGGAGAGGCTCTTCCACAAA
  CTGTTTTCTCATTACAACCAGTTCATCAGGCCTGTGGAAAACGTTTCCGACCCTGTCACG
  GTACACTTTGAAGTGGCCATCACCCAGCTGGCCAACGTGGATGAAGTAAACCAGATCATG
  GAAACCAATTTGTGGCTGCGTCACATCTGGAATGATTATAAATTGCGCTGGGATCCAATG
  GAATATGATGGCATTGAGACTCTTCGCGTTCCTGCAGATAAGATTTGGAAGCCCGACATT
  GTTCTCTATAACAATGCTGTTGGTGACTTCCAAGTAGAAGGCAAAACAAAAGCTCTTCTT
  AAATACAATGGCATGATAACCTGGACTCCACCAGCTATTTTTAAGAGTTCCTGCCCTATG
  GATATCACCTTTTTCCCTTTTGATCATCAAAACTGTTCCCTAAAATTTGGTTCCTGGACG
  TATGACAAAGCTGAAATTGATCTTCTAATCATTGGATCAAAAGTGGATATGAATGATTTT
  TGGGAAAACAGTGAATGGGAAATCATTGATGCCTCTGGCTACAAACATGACATCAAATAC
  AACTGTTGTGAAGAGATATACACAGATATAACCTATTCTTTCTACATTAGAAGATTGCCG
  ATGTTTTACACGATTAATCTGATCATCCCTTGTCTCTTTATTTCATTTCTAACCGTGTTG
  GTCTTTTACCTTCCTTCGGACTGTGGTGAAAAAGTGACGCTTTGTATTTCAGTCCTGCTT
  TCTCTGACTGTGTTTTTGCTGGTCATCACAGAAACCATCCCATCCACATCTCTGGTGGTC
  CCACTGGTGGGTGAGTACCTGCTGTTCACCATGATCTTTGTCACACTGTCCATCGTGGTG
  ACTGTGTTTGTGTTGAACATACACTACCGCACCCCAACCACGCACACAATGCCCAGGTGG
  GTGAAGACAGTTTTCCTGAAGCTGCTGCCCCAGGTCCTGCTGATGAGGTGGCCTCTGGAC
  AAGACAAGGGGCACAGGCTCTGATGCAGTGCCCAGAGGCCTTGCCAGGAGGCCTGCCAAA
  GGCAAGCTTGCAAGCCATGGGGAACCCAGACATCTTAAAGAATGCTTCCATTGTCACAAA
  TCAAATGAGCTTGCCACAAGCAAGAGAAGATTAAGTCATCAGCCATTACAGTGGGTGGTG
  GAAAATTCGGAGCACTCGCCTGAAGTTGAAGATGTGATTAACAGTGTTCAGTTCATAGCA
  GAAAACATGAAGAGCCACAATGAAACCAAGGAGGTAGAAGATGACTGGAAATACGTGGCC
  ATGGTGGTGGACAGAGTATTTCTTTGGGTATTTATAATTGTCTGTGTATTTGGAACTGCA
  GGGCTATTTCTACAGCCACTACTTGGGAACACAGGAAAATCTTAA
  
  Clone variation with respect to NM_004198.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004198 unedited
  AAAGTTCGAATTTTGTAATACGACTCACTATAGNNGGCGGCCGCGNAATTNNCGGCACGA
  GGCCCACAATCCTNNTTGCCTAGGAAAAAGGAATCCAAGTGTGTTTTAACCATGCTGACC
  AGCAAGGGGCAGGGATTCCTTCATGGGGGCTTGTGTCTCTGGCTGTGTGTGTTCACACCT
  TTCTTTAAAGGCTGTGTGGGCTGTGCAACTGAGGAGAGGCTCTTCCACAAACTGTTTTCT
  CATTACAACCAGTTCATCAGGCCTGTGGAAAACGTTTCCGACCCTGTCACGGTACACTTT
  GAAGTGGCCATCACCCAGCTGGCCAACGTGGATGAAGTAAACCAGATCATGGAAACCAAT
  TTGTGGCTGCGTCACATCTGGAATGATTATAAATTGCGCTGGGATCCAATGGAATATGAT
  GGCATTGAGACTCTTCGCGTTCCTGCAGATAAGATTTGGAAGCCCGACATTGTTCTCTAT
  AACAATGCTGTTGGTGACTTCCAAGTAGAAAGCAAAACAAAAGCTCTTCTTAAATACAAT
  GGCATGATAACCTGGACTCCACCAGCTATTTTTAAGAGTTCCTGCCCTATGGATATCACC
  TTTTTCCCTTTTGATCATCAAAACTGGTCCCTAAAATTTGGTTCCTGGACGTATGACAAA
  GCTGAAATTGAATCTCTAATCATTGGATCAAAAGTGGATATGAATGATTTTTGGGAAAAC
  AGTGAATGGGGAAATCATTGATGCCTCTGGCTACAAAATGACATCAAATACAACTGGTGT
  GAAGAGATATTCCCAGATTTACCCTATTCTTTCTACATATAAAGATTGGCAATGTTTTAC
  ACGATTAAACTGAATCAACCCTTGGCCCTTTATTTTATTTTTCAACCGGGTGGNGCTTTT
  ACCCTCCCCTCCGACCGGTGGTGAAAAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004198 unedited
  AGGGGNNGTTGGTTNNNTTTGCATGCAGTGCACTTCCAGGCCAGGAGAGGCACTGGGGAG
  GGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATC
  TAGAGTCGAGTTTTTTTTTTTTTTTTTTTAAAACTAACAATCAGTGTATCAAATAATGCT
  GAGGAGGGTGAGTTACATTACAGAGACCTGCCCAAGAAATCAAGGATGCCATAGTTCACA
  AAGTGTTGCAAACAGTTCACAAATGTTGCATGGTCCAATTCCCAGAGTTCACCTGTCACA
  TGTCATAATACTGAGAAACAGCATCCACTGGAGGTACAGCAGAACTTTTTAGTGTGGCTT
  GATGTTAATTACATAATTAGGCTGTATTGTAAGTCATTCTTGTCTTTAGAAGCCAAACAC
  ACAGACACGAGAAACCTGACCTGATACTGTAGCCGTGGGTGCTGCCCAATCAGGGCACTA
  ATGTCATAACACTTCTCACTTCTCCCCCTGTGCTACACTGGAGGATATTCTGCTTCCTAA
  TGTGCAAGAAAGTCCTCTTTTTCCATGTAGCCATCAGTTTTAACAAATGGGGGACTTGGG
  TGGGAAGCCTTTGCTTTCCTTTCCTTGGGGCCAGGAATGCAAAACAAATATGGGGGCTGG
  AAATTTCTGAACATNAAAGAAAATACATTTTAAAAATTTTCTGTGTTCCCAATTATGGGC
  TGTGAATAGCCCTGCATTTCCAAATCCCGACCATTATAATTCCCCAAGAAATACTCTGTC
  ACCCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_004198
• ORF Size: 1485 bp
• Insert Size: 2000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004198.2, NP_004189.1
• RefSeq Size: 2090
• RefSeq ORF: 1485
• Locus ID: 8973
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Gene Summary: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).