Dopamine Receptor D4 (DRD4) (NM_000797) Human Untagged Clone

CAT#: SC124155

DRD4 (untagged)-Human dopamine receptor D4 (DRD4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DRD4
• Synonyms: D4DR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000797 edited
  GCATGGGGAACCGCAGCACCGCGGACGCGGACGGGCTGCTGGCTGGGCGCGGGCCGGCCG
  CGGGGGCATCTGCGGGGGCATCTGCGGGGCTGGCTGGGCAGGGCGCGGCGGCGCTGGTGG
  GGGGCGTGCTGCTCATCGGCGCGGTGCTCGCGGGGAACTCGCTCGTGTGCGTGAGCGTGG
  CCACCGAGCGCGCCCTGCAGACGCCCACCAACTCCTTCATCGTGAGCCTGGCGGCCGCCG
  ACCTCCTCCTCGCTCTCCTGGTGCTGCCGCTCTTCGTCTACTCCGAGGTCCAGGGTGGCG
  CGTGGCTGCTGAGCCCCCGCCTGTGCGACGCCCTCATGGCCATGGACGTCATGCTGTGCA
  CCGCCTCCATCTTCAACCTGTGCGCCATCAGCGTGGACAGGTTCGTGGCCGTGGCCGTGC
  CGCTGCGCTACAACCGGCAGGGTGGGAGCCGCCGGCAGCTGCTGCTCATCGGCGCCACGT
  GGCTGCTGTCCGCGGCGGTGGCGGCGCCCGTACTGTGCGGCCTCAACGACGTGCGCGGCC
  GCGACCCCGCCGTGTGCCGCCTGGAGGACCGCGACTACGTGGTCTACTCGTCCGTGTGCT
  CCTTCTTCCTACCCTGCCCGCTCATGCTGCTGCTCTACTGGGCCACGTTCCGCGGCCTGC
  AGCGCTGGGAGGTGGCACGTCGCGCCAAGCTGCACGGCCGCGCGCCCCGCCGACCCAGCG
  GCCCTGGCCCGCCTTCCCCCACGCCACCCGCGCCCCGCCTCCCCCAGGACCCCTGCGGCC
  CCGACTGTGCGCCCCCCGCGCCCGGCCTTCCCCGGGGTCCCTGCGGCCCCGACTGTGCGC
  CCGCCGCGCCCAGCCTCCCCCAGGACCCCTGTGGCCCCGACTGTGCGCCCCCCGCGCCCG
  GCCTCCCCCCGGACCCCTGCGGCTCCAACTGTGCTCCCCCCGACGCCGTCAGAGCCGCCG
  CGCTCCCACCCCAGACTCCACCGCAGACCCGCAGGAGGCGGCGTGCCAAGATCACCGGCC
  GGGAGCGCAAGGCCATGAGGGTCCTGCCGGTGGTGGTCGGGGCCTTCCTGCTGTGCTGGA
  CGCCCTTCTTCGTGGTGCACATCACGCAGGCGCTGTGTCCTGCCTGCTCCGTGCCCCCGC
  GGCTGGTCAGCGCCGTCACCTGGCTGGGCTACGTCAACAGCGCCCTCAACCCCGTCATCT
  ACACTGTCTTCAACGCCGAGTTCCGCAACGTCTTCCGCAAGGCCCTGCGTGCCTGCTGCT
  GAGCCGGGCACCCCCGGACGCCCCCCGGCCTGATGGCCAGGCCTCAGGGACCAAGGAGAT
  GGGGAGGGCGCTTTTGTACGTTAATTAAACAAATTCCTTCCCAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000797 unedited
  AGTGTCAGCTCTCGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCATGGGGAACCG
  CAGCACCGCGGACGCGGACGGGCTGCTGGCTGGGCGCGGGCCGGCCGCGGGGGCATCTGC
  GGGGGCATCTGCGGGGCTGGCTGGGCAGGGCGCGGCGGCGCTGGTGGGGGGCGTGCTGCT
  CATCGGCGCGGTGCTCGCGGGGAACTCGCTCGTGTGCGTGAGCGTGGCCACCGAGCGCGC
  CCTGCAGACGCCCACCAACTCCTTCATCGTGAGCCTGGCGGCCGCCGACCTCCTCCTCGC
  TCTCCTGGTGCTGCCGCTCTTCGTCTACTCCGAGGTCCAGGGTGGCGCGTGGCTGCTGAG
  CCCCCGCCTGTGCGACGCCCTCATGGCCATGGACGTCATGCTGTGCACCGCCTCCATCTT
  CAACCTGTGCGCCATCAGCGTGGACAGGTTCGTGGCCGTGGCCGTGCCGCTGCGCTACAA
  CCGGCAGGGTGGGAGCCGCCGGCAGCTGCTGCTCATCGGCGCCACGTGGCTGCTGTCCGC
  CGCGGTGGCGGCGCCCGTACTGTGCGGGCTCAACGACATGTGGCGGCCCCTACTCCGTCC
  GTGTTGCCCCTGGAGGACCGCCACTTCCTGGTCCATTCGTCCGGGTGCGTCATTTTTCCT
  CCCAGCCCGTTATTGCGGTGCGCATTCTGGGGCCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000797 unedited
  TTCCTGCATGTCAACTTCACGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCAC
  CCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTT
  TTTTTTTTTTGGGAAGGAATTTGTTTAATTAACGTACAAAAGCGCCCTCCCCATCTCCTT
  GGTCCCTGAGGCCTGGCCATCAGGCCGGGGGGCGTCCGGGGGTGCCCGGCTCAGCAGCAG
  GCACGCAGGGCCTTGCGGAAGACGTTGCGGAACTCGGCGTTGAAGACAGTGTAGATGACG
  GGGTTGAGGGCGCTGTTGACGTAGCCCAGCCAGGTGACGGCGCTGACCAGCCGCGGGGGC
  ACGGAGCAGGCAGGACACAGCGCCTGCGTGATGTGCACCACGAAGAAGGGCGTCCAGCAC
  AGCAGGAAGGCCCCGACCACCACCGGCAGGACCCTCATGGCCTTGCGCTCCCGGCCGGTG
  ATCTTGGCACGCCGCCTCCTGCGGGTCTGCGGTGGAGTCTGGGGTGGGAAGCGCGCGGCT
  CTGACGGCGTCGGGGGGAGCACAGTTGGAGCCGCANGGGTTCCGGGGGGAGGCGGCCNCC
  GGGGCCCACANTCCGGGCCACGGGGTCCTTGGGGGAGCTGGCNCGGCNGCNCACCATCCG
  GGCGCAGGAACCCCCGGGAAGCCG
  
• Restriction Sites: Please inquire
• ACCN: NM_000797
• ORF Size: 1260 bp
• Insert Size: 900
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_000797.2, NP_000788.2
• RefSeq Size: 1360
• RefSeq ORF: 1260
• Locus ID: 1815
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]