Mucolipin 3 (MCOLN3) (NM_018298) Human Untagged Clone

CAT#: SC124160

MCOLN3 (untagged)-Human mucolipin 3 (MCOLN3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCOLN3
• Synonyms: TRP-ML3; TRPML3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124160 sequence for NM_018298 edited (data generated by NextGen Sequencing)
  ATGGCAGATCCTGAGGTAGTTGTGAGTAGCTGCAGCTCTCATGAAGAGGAAAATCGCTGC
  AATTTTAACCAGCAAACATCTCCATCTGAGGAGCTTCTATTAGAAGACCAGATGAGGCGA
  AAACTCAAATTTTTTTTCATGAATCCCTGTGAGAAGTTCTGGGCTCGAGGTAGAAAACCA
  TGGAAACTTGCCATACAAATTCTAAAAATTGCAATGGTGACTATCCAGCTGGTCTTATTT
  GGGCTAAGTAACCAGATGGTGGTAGCTTTCAAGGAAGAGAATACTATAGCATTCAAACAC
  CTTTTCCTAAAAGGATATATGGACCGAATGGATGACACATATGCAGTGTACACACAAAGT
  GACGTGTATGATCAGTTAATCTTCGCAGTAAACCAGTACTTGCAGCTATACAATGTCTCC
  GTTGGGAATCATGCTTATGAGAACAAAGGTACCAAGCAATCTGCTATGGCAATCTGTCAG
  CACTTCTACAAGCGAGGAAACATCTACCCTGGAAATGATACCTTTGACATCGATCCAGAA
  ATTGAAACTGAGTGTTTCTTTGTGGAGCCAGATGAACCTTTTCACATTGGGACACCAGCA
  GAAAATAAACTGAACTTAACACTGGACTTCCACAGACTCCTAACAGTGGAGCTTCAGTTT
  AAACTGAAAGCCATTAATCTGCAGACAGTTCGTCATCAAGAACTCCCTGACTGTTATGAC
  TTTACTCTGACTATAACATTTGACAACAAGGCCCATAGTGGAAGAATTAAAATAAGTTTA
  GATAATGACATTTCCATCAGAGAATGTAAAGACTGGCATGTATCTGGATCAATTCAGAAG
  AACACTCATTACATGATGATCTTTGATGCCTTTGTCATTCTGACTTGCTTGGTTTCATTA
  ATCCTCTGCATTAGATCTGTGATTAGAGGACTTCAGCTTCAGCAGGAGTTTGTCAATTTT
  TTCCTCCTCCATTATAAGAAGGAAGTTTCTGTTTCTGATCAAATGGAATTTGTCAATGGA
  TGGTACATTATGATTATTATTAGTGACATATTGACAATCATTGGATCAATTCTAAAAATG
  GAAATCCAAGCTAAGAGTCTAACTAGTTATGATGTCTGTAGCATACTTCTTGGGACTTCT
  ACCATGCTTGTGTGGCTTGGAGTCATCCGATACCTCGGTTTCTTTGCAAAGTACAACCTC
  CTCATTTTGACCCTTCAGGCAGCGCTGCCCAATGTCATCAGGTTCTGCTGCTGTGCAGCT
  ATGATTTACTTAGGTTACTGCTTCTGTGGATGGATCGTGCTGGGGCCTTACCATGACAAG
  TTTCGTTCTCTGAACATGGTCTCTGAGTGCCTTTTCTCTCTGATAAATGGAGATGATATG
  TTTGCCACGTTTGCAAAAATGCAGCAAAAAAGTTACTTAGTCTGGCTGTTTAGTAGAATT
  TACCTCTACTCATTCATCAGCCTCTTTATATATATGATTTTAAGTCTTTTCATTGCACTG
  ATCACTGATACATACGAAACAATTAAGCAATACCAACAAGATGGCTTCCCAGAGACTGAA
  CTTCGTACATTTATATCAGAATGCAAAGATCTACCCAACTCTGGAAAATACAGATTAGAA
  GATGACCCTCCAGTATCTTTATTCTGCTGTTGTAAAAAGTAG
  
  Clone variation with respect to NM_018298.9
  1149 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018298 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTGCTGGAGTCGCT
  CGCTGACTCGCCCTGCGCCCTCGCCGCGGACACCGGAGCTGCGGCCGCTCCCCGCTGTCC
  CCCAGAGATGGCAGATCCTGAGGTAGTTGTGAGTAGCTGCAGCTCTCATGAAGAGGAAAA
  TCGCTGCAATTTTAACCAGCAAACATCTCCATCTGAGGAGCTTCTATTAGAAGACCAGAT
  GAGGCGAAAACTCAAATTTTTTTTCATGAATCCCTGTGAGAAGTTCTGGGCTCGAGGTAG
  AAAACCATGGAAACTTGCCATACAAATTCTAAAAATTGCAATGGTGACTATCCAGCTGGT
  CTTATTTGGGCTAAGTAACCAGATGGTGGTAGCTTTCAAGGAAGAGAATACTATAGCATT
  CAAACACCTTTTCCTAAAAGGATATATGGACCGAATGGATGACACATATGCAGTGTACAC
  ACAAAGTGACGTGTATGATCAGTTAATCTTCGCAGTAAACCAGTACTTGCAGCTATACAA
  TGTCTCCGTTGGGAATCATGCTTATGAGAACAAAGGTACCAAGCAATCTGCTATGGCAAT
  CTGTCAGCACTTCTACAAGCGAGGAAACATCTACCCTGGAAATGATACCTTTGACATCGA
  TCCAGAAATTGAAACTGAGTGTTTCTTTGTGGAGCCAGATGAACCTTTTCACATTGGGAC
  ACCAGCAGAAAATAAACTGAACTTAACAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018298 unedited
  CAACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGT
  TCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTT
  TGCATTTGGTATATGCTTTAATTTCATGCATGTATAAGATACTCTTTTTACTTTCTACTT
  TAACACTGAAGGAGGATAGAAAACTTGTAAATGAGTATTTAAAAGCCTGATCCTCTTAAG
  AACTAAAAGCAGAATCAAGTAACAGTTGGCTTTCATAACCAAATACAGTCACATGCTGGA
  TAACGATGTTTTGGTCAATGATGTACCGCATATACAATGGTGGTCCCAGAAGATTATAAA
  ACCATATTTTTACTGTCCCTTTTCTATGTTTAGATACTTACCATTGTGTTACAATTGCCT
  ACTGTATTCAATACAGTAACATGTTGTACAGATTTGTACCCCAGGACCAACAGGCTATAC
  CAAATAGCCTAGGTGTGTAGTAGGCTATACCATCTAGGTTTGTGGAAGTACATGCTATGA
  TGTTTAATGACAAAATCGCCTAATGACACATTTCTCAGAACATATCTCCATCCTTAAGTG
  ACATATGGCCGTATCACATTGTTAGCTGGTGCGCTCTTATTCTGGTGCGCTCTTATTCTG
  GTGCACTCTTATTCTTCCTTTCAAGAGAAGATTTTAAAATGCAATGATTACTGTATAAAT
  GGTAACTACACCCACTCTCTCAAGGATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018298
• ORF Size: 1662 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_018298.9, NP_060768.8
• RefSeq Size: 2813
• RefSeq ORF: 1662
• Locus ID: 55283
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Gene Summary: This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).