IFITM2 (NM_006435) Human Untagged Clone

CAT#: SC124192

IFITM2 (untagged)-Human interferon induced transmembrane protein 2 (1-8D) (IFITM2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFITM2
• Synonyms: 1-8D; DSPA2c
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124192 sequence for NM_006435 edited (data generated by NextGen Sequencing)
  ATGAACCACATTGTGCAAACCTTCTCTCCTGTCAACAGCGGCCAGCCTCCCAACTACGAG
  ATGCTCAAGGAGGAGCAGGAAGTGGCTATGCTGGGGGCGCCCCACAACCCTGCTCCCCCG
  ATGTCCACCGTGATCCACATCCGCAGCGAGACCTCCGTGCCTGACCATGTCGTCTGGTCC
  CTGTTCAACACCCTCTTCATGAACACCTGCTGCCTGGGCTTCATAGCATTCGCCTACTCC
  GTGAAGTCTAGGGACAGGAAGATGGTTGGCGACGTGACCGGGGCCCAGGCCTATGCCTCC
  ACCGCCAAGTGCCTGAACATCTGGGCCCTGATTTTGGGCATCTTCATGACCATTCTGCTC
  ATCATCATCCCAGTGTTGGTCGTCCAGGCCCAGCGATAG
  
  Clone variation with respect to NM_006435.2
  98 t=>c;171 g=>c;234 g=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006435 unedited
  TTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCCGATCACCGCTGG
  TCACCATGAACCACATTGTGCAAACCTTCTCTCCTGTCAACAGCGGCCAGCCTCCCAACT
  ACGAGATGCTCAAGGAGGAGCAGGAAGTGGCTATGCTGGGGGCGCCCCACAACCCTGCTC
  CCCCGATGTCCACCGTGATCCACATCCGCAGCGAGACCTCCGTGCCTGACCATGTCGTCT
  GGTCCCTGTTCAACACCCTCTTCATGAACACCTGCTGCCTGGGCTTCATAGCATTCGCCT
  ACTCCGTGAAGTCTAGGGACAGGAAGATGGTTGGCGACGTGACCGGGGCCCAGGCCTATG
  CCTCCACCGCCAAGTGCCTGAACATCTGGGCCCTGATTTTGGGCATCTTCATGACCATTC
  TGCTCATCATCATCCCAGTGTTGGTCGTCCAGGCCCAGCGATAGATCAGGAGGCATCATT
  GAGGCCAGGAGCTCTGCCCGTGACCTGTATCCCACGTACTCTATCTTCCATTCCTCGCCC
  TGCCCCCAGAGGCCAGGAGCTCTGCCCTTGACCTGTATTCCACTTACTCCACCTTCCATT
  CCTCGCCCTGTCCCCACAGCCGAGTCCTGCATCAGCCCTTTATCCTCACACGCTTTTCTA
  CAATGGCATTCAATAAAGTGTATANTGTTTCTGGTAAAAAAAAAAAAAAAAACTCGACTC
  TAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCNTGTGAC
  CCCTCCCCGTGCCTCTCCTGGCCCCTGAAGTTGCCACTNCAGTGCCCACCAGCCTTTGTC
  TAATAAAATAAAGTGCATCATTTTGTCTGACTANGGTGTCTCATAATATGTGGGGGGGGG
  GGGGGGGNGTGGNNNNNNNNNNNGGGAGGGGGNNNTNGGAGAGAAAACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006435 unedited
  NNTTATCTCTGNNACCGCGGCCCGCATTCTNANNATCGAGTTTTTTTTTTTTTTTTTTAC
  CAAAAACATATACACTTTATTGAATGCCATTGTAGAAAAGCGTGTGAGGATAAAGGGCTG
  ATGCAGGACTCGGCTGTGGGGACAGGGCGAGGAATGGAAGGTGGAGTAAGTGGAATACAG
  GTCAAGGGCAGAGCTCCTGGCCTCTGGGGGCAGGGCGAGGAATGGAAGATAGAGTACGTG
  GGATACAGGTCACGGGCAGAGCTCCTGGCCTCAATGATGCCTCCTGATCTATCGCTGGGC
  CTGGACGACCAACACTGGGATGATGATGAGCAGAATGGTCATGAAGATGCCCAAAATCAG
  GGCCCAGATGTTCAGGCACTTGGCGGTGGAGGCATAGGCCTGGGCCCCGGTCACGTCGCC
  AACCATCTTCCTGTCCCTAGACTTCACGGAGTAGGCGAATGCTATGAAGCCCAGGCAGCA
  GGTGTTCATGAAGAGGGTGTTGAACAGGGACCAGACGACATGGTCAGGCACGGAGGTCTC
  GCTGCGGATGTGGATCACGGTGGACATCGGGGGAGCAGGGTTGTGGGGCGCCCCCAGCAT
  AGCCACTTCCTGCTCCTCCTTGAGCATCTCGTANTTGGGAGGCTGGCCGCTGTTGACAGG
  AGAGAAAGGTTGCACAATGTGGTTCATGGTGACCCAGCGTGATCGGGCCTCGTGCCGAAT
  TCGCGGCCGCCCTATAGTGAGTCGTATTACAAATTCTGACGGTTCACTAAACGAGCTCTG
  CTTTATAGACCTNCCACCGTACACGCCTACCGNCCATTTGCGTCACGGGGGCGGGGNTAT
  TACCACATTTTGAAAGGCCCNGTGATTTTGGTGCCAAACAAACTCCNATTGACGTCAATG
  GGGTGGAAACTTGGAAAATCCCGTGAGTCAAACCGTTATCACGCCCATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006435
• ORF Size: 399 bp
• Insert Size: 670
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006435.1, NP_006426.1
• RefSeq Size: 905
• RefSeq ORF: 399
• Locus ID: 10581
• Domains: CD225
• Protein Families: Transmembrane
• Gene Summary: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. [UniProtKB/Swiss-Prot Function]