SOCS5 (NM_144949) Human Untagged Clone

CAT#: SC124288

SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2


  "NM_144949" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SOCS5
Synonyms CIS6; Cish5; CISH6; SOCS-5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_144949, the custom clone sequence may differ by one or more nucleotides


ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGTCATGAGGGAG
GAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCAT
AGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGC
CCTTCGAAGAATTCTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCA
TCGAAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACA
TGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA
AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCTGTACACGACA
TGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGGTTGCAGGATACTGTGGGCTT
GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTTTTCCAATAAAAGAAAAATCCATCTC
TCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTA
AACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTAC
AGAAGATGAAGAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC
AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAATTAG
CTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCTAATTGTGACTCGGAAGAGGA
TACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAGCGTCAGATATCTGGAGACAGCCATACCCAT
GTTAGCAGACAGGGAGCTTGGAAAGTCCACACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGC
TTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGG
GAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC
CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGACGCCCATGACC
CGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAAGATCCCAGTTCGTGCATGTT
TTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTCCCTTTTAGCCTGCAGTATATCTGTCGCGCG
GTAATCTGCAGGTGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTT
TAAAAGAGTATCATTATAAACAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAGTA
A


>OriGene 5' read for NM_144949 unedited
GGTGTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCGGGGG
CATCCGGCGGAGCTGGGGTCCCCGGGCTCCGTCCGGAGGAAGCGACGCTGCGCTCGCTGG
GCAGTCGGAGGGGACGGGACGCACCGGAGGGCAGGCGGACTCGCCCTGTCGGTGACTGCG
CCGTCCGGGCCCGTCCTGCCTGGCCGCAGGTGCCCTGGATGAGGCCGCCCCGCGCGCCCC
AAACGATTTTATAATCAATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGT
GTCAGAATCTCTTCGGTCATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCA
ACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAAC
AAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATT
CTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCG
AAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACT
CTCGACATGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTT
CATTGGATGCTGATAAAAAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGC
GCTACGGCGTAAGTTCTGTACACGACATGGACAGTGTTTCCAGCAGAACTGTAGGAAGTC
GCTCTCTAGAACAGAGTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTTACAG
CAGCAGTCAAAGCCTCTCTTTTTCCATAAAAAGAAAATTCATCTCTCTGAATAATGCTTG
AGAAATGCCTTTTNCTGCTGGCTCAGATTNAGCCCAAATG
>OriGene 3' read for NM_144949 unedited
ACTATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTCATGCTG
GTGATTTTTCTTTTTTAAAATGTAAGCCACTAATATTTTAAGACAAAAATTTAAACCAAA
AATTGCATATTAATATTATACACAAACTGAAACATGTGACTTTTAGCACAGTGTATACAT
GCTTACATAAACTCAAACACATTTAAAACAATTTCCATTTAACATATGAAAGTTTTGAAA
TACATAAAAGCATTAATACTTTCTATAAAACTACAGTTAGAACATCAATTTGCTACAAGC
ATATAAAAACATCAAGTGCTTTCTTGGAGTTTCAAGTTTCCTCTCTAAAACACAATCTTG
CTCACATATATAGTCCTTTTCCAATAATCAGTATGAACTTTTCTTTTTCTCAAGAGGTTT
ATTTTCCAGGTACATTATAAGCTCAAGAAAAAAGACCCAACAATTAGGCAATATAATTAT
GTCATAACAACTTAATTGCACATAATGCTTTAAAGTAGGTTTGGATGAAGTTCTCAAACA
CTTTGGTATATGATCTTCAGGGACTTTAATTAGAAACAACAGAAATTATAAGTCCCTTCA
ATCCCCATTTTGCTTTAAAAGGGACAAGTCTTTGGTTAAAGTTCTACATTTTGGGCATTT
ATTTTTAATTAGATGGTCCCCAAACAATAAATGTACTGATCTATACAAATTCACAGACTT
ATTTACCTGCTTCTGAGCAGTGGGAGTTACAGAACTCATTACTATATATGTCATGGGAAG
TTTCAATCTTCATTTATAGCAGAGAATCAAAGGTTATTACTTCTCTGTCAGTTTCTGTTA
TACCTAACTGTCAGTATTTGCAGTAACTACGATCTGTTCCCAGTTTATATTATGACTGAT
AGATGNGAGCATTAATTTAAGTAGCTATTCTGATAGTCATATAGACTGTCATAC
Restriction Sites NotI-NotI     
ACCN NM_144949
ORF Size 1611 bp
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_144949.2, NP_659198.1
RefSeq Size 4510
RefSeq ORF 1611
Locus ID 9655
Domains SH2, SOCS
Protein Families Druggable Genome
Protein Pathways Jak-STAT signaling pathway
Gene Summary The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.

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