H2AFV (NM_138635) Human Untagged Clone

CAT#: SC124291

H2AFV (untagged)-Human H2A histone family, member V (H2AFV), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: H2AFV
• Synonyms: H2A.Z-2; H2AV
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124291 sequence for NM_138635 edited (data generated by NextGen Sequencing)
  ATGGCTGGAGGCAAAGCTGGAAAGGACAGTGGGAAGGCCAAGGCTAAGGCAGTATCTCGC
  TCACAGAGAGCTGGGCTACAGTTTCCTGTGGGCCGCATCCACAGACACTTGAAGACTCGC
  ACCACAAGCCATGGAAGGGTGGGTGCCACTGCTGCCGTGTACAGTGCTGCGATTCTGGAG
  TACCTCACTGCAGAGGTGCTGGAGCTGGCAGGTAATGCTTCTAAGGATCTCAAAGTAAAG
  CGTATCACTCCGCGTCACTTGCAGCTTGCAATCCGTGGTGATGAAGAGTTGGATTCTCTT
  ATCAAGGCTACCATAGCTGGGGGTGAGAAGAGAAGGTGTTCTTAG
  
  Clone variation with respect to NM_138635.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138635 unedited
  GTAAGTCAAATTTTGTAAACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGGCGGG
  TCGGCAGCGGGAGGGCGCGCGGCCGAGCGGAGGCGGAGTCGGCGCCGAGAACATGGCTGG
  AGGCAAAGCTGGAAAGGACAGTGGGAAGGCCAAGGCTAAGGCAGTATCTCGCTCACAGAG
  AGCTGGGCTACAGTTTCCTGTGGGCCGCATCCACAGACACTTGAAGACTCGCACCACAAG
  CCATGGAAGGGTGGGTGCCACTGCTGCCGTGTACAGTGCTGCGATTCTGGAGTACCTCAC
  TGCAGAGGTGCTGGAGCTGGCAGGTAATGCTTCTAAGGATCTCAAAGTAAAGCGTATCAC
  TCCGCGTCACTTGCAGCTTGCAATCCGTGGTGATGAAGAGTTGGATTCTCTTATCAAGGC
  TACCATAGCTGGGGGTGAGAAGAGAAGGTGTTCTTAGATCAGAAGATGCCATTGTATTAG
  GTGACGGCAAGGTTTTGCTGATTTAGTGGAACAAGATTCTACTGGGATGTGTGCTGAGCT
  GAACCAAGGAACTGCCCGAATGTGCTGAACAAGGACATTTGCTTCTCAGATACGTGAATT
  CAATTTTAAGCAAGATTCTTGATCTGCTTCAGAGCAGCTTTGATTTAAAGTAATTTCAGA
  GCACTTTTCCTTGCATGAGTAATTTTCTGAATGTATAAAATATTCTATTTATGTCTGACC
  TTTTGGATAAACTGTGTTGCTGCAGTGTTGGTCCACACTACCATCCTAAGTGAAGACTTA
  GTAAGTCTGAGGATCTCCAGGCACTGGAAAGAGTGCAGACCTGGCACTGAAATGGTATAG
  CTAGTGGTCATTCTTCGGGTTTCGCCTCATACGGAGTCCTGACGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_138635
• ORF Size: 345 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_138635.2, NP_619541.1
• RefSeq Size: 825
• RefSeq ORF: 345
• Locus ID: 94239
• Domains: histone
• Protein Families: Druggable Genome
• Protein Pathways: Systemic lupus erythematosus
• Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]
  Transcript Variant: This variant (2) utilizes an alternate exon in the 3' coding region and 3' UTR, compared to variant 1. It encodes a shorter protein (isoform 2) compared to that encoded by variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.