MAL (NM_022440) Human Untagged Clone

CAT#: SC124307

MAL (untagged)-Human mal, T-cell differentiation protein (MAL), transcript variant d

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAL
• Synonyms: MVP17; VIP17
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_022440, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCCCGCAGCGGCGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACCACCTTGCCCG
  ACTTGCTCTTCATCTTTGAGTTTGTGTTCTCCTACATAGCCACTCTGCTCTACGTGGTCCATGCGGTGTT
  CTCTTTAATCAGATGGAAGTCTTCATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022440 unedited
  TCAAAATTTGTATACGACTCATATAGGCGGCCGCGACTTCGGCACGAGGAGCCAGCGAGA
  GGTCTGCGCGGAGTCTGAGCGGCGCTCGTCCCGTCCCAAGGCCGACGCCAGCACGCCGTC
  ATGGCCCCCGCAGCGGCGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACC
  ACCTTGCCCGACTTGCTCTTCATCTTTGAGTTTATCTTCGGGGGCCTGGTGTGGATCCTG
  GTGGCCTCCTCCCTGGTGCCCTGGCCCCTGGTCCAGGGCTGGGTGATGTTCGTGTCTGTG
  TTCTGCTTCGTGGCCACCACCACCTTGATCATCCTGTACATAATTGGAGCCCACGGTGGA
  GAGACTTCCTGGGTCACCTTGGACGCAGCCTACCACTGCACCGCTGCCCTCTTTTACCTC
  AGCGCCTCAGTCCTGGAGGCCCTGGCCACCATCACGATGCAAGACGGCTTCACCTACAGG
  CACTACCATGAAAACATTGCTGCCGTGGTGTTCTCCTACATAGCCACTCTGCTCTACGTG
  GTCCATGCGGTGTTCTCTTTAATCAGATGGAAGTCTTCATAAAGCCGCAGTAGAACTTGA
  GCTGAAAACCCAGATGGTGTTAACTGGCCGCCCCACTTTCCGGCATAACTNTTTAGAAAA
  CAGAAATGCCCTTGATGGTGGAAAAAAGAAAACAACCACCCCCCCACTGCCCAAAAANAA
  AGCCCTGCCCTGTTGCTCGTGGGTGCTGTGTTACTCTCCGTGTGCCTTCCGTNCGGTTGG
  GAGCTGCTGGTCTACCTNCACTGCTGGCTGCTGCTAGGTCACTNCTGTTGTGAAGGGACC
  TCTTGTCGGGGTGGGAAGTGCGACCGGACTGAAAGAAAAGATCTTTGTGACCTGGACAGT
  TCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022440 unedited
  CGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGAACATTAAAACTTTTATAAA
  GTATTTCACAGGGTTATCGTCTTCCACCATGGACCTCTGGAAAGATCTGTTGGGTGAGTT
  TTAGTCCCCATGACATGCAGAACATCCATGAAGACTTAAAACATGGCACAAGATGGGGCG
  CTCGGGAGAGCTTGTGGACAATACCAACAGGTAGTTCTCGAGAGCTGCTCCAGGGGTCAG
  CAGAGGATCTTTCTTTCCTTCTCAGGTCACGGTCGCCACTTCCCACCCCCGAACAAGAAG
  GTCCCCTTTCACAAACAGGAGGTGACCCTAGCAGACAGCACAGCAGTTGGAGGTTAGACA
  CAGCAAGCTCCCAACCCGGACGCGAAGGCACACGGGAGAGTAAACACAGCACCCACGAGC
  AACAGGGCAGGGCTTTTTTTTTTTGGGCAGTGGGGGGGTGGTTGTTTTCTTTTTTCCACC
  ATCAAGGGCATTTCTGTTTTCTAAAAAGTTATGCCGGAAAGTGGGGCGGCCAGTTAACAC
  CATCTGGGTTTTCAGCTCAAGTTCTACTGCGGCTTTATGAAGACTTCCATCTGATTAAAG
  AGAACACCGCATGGACCACGTAGAGCAGAGTGGCTATGTAAGAGAACACCACGGCAGCAA
  TGTTTTCATGGTAGTGCCTGTAAGTGAAACCCCCCTGCATCGCGATGGTGGCCACGGCCT
  CCATGACTGAAGCGCCGAAGTAAAAGAAGGCAACGGTGCCATTGGTAAGCTGCCCTCCAA
  GTGACCCAAGAAATCTCTTCACCCGGGGCTCCAATCTTGTCCAAGATGATCCAAGGGGCG
  GGTGCCCCCGAATCAAAACACATACCGAACTCTCCCCACCCCTGGACAGGGGCCAGGGCC
  CCCGGGAGAAGCCCCCAGTATCCACCCAGGCCCCGAGAAATAACCCAAGAAAAAAACAGT
  CGCGCACGTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022440
• Insert Size: 1110 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_022440.1, NP_071885.1
• RefSeq Size: 762 bp
• RefSeq ORF: 168 bp
• Locus ID: 4118
• Cytogenetics: 2q11.1
• Protein Families: Transmembrane
• Gene Summary: 'The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]'
  Transcript Variant: This variant (d) is missing alternatively spliced exons 2 and 3, resulting in the shortest isoform (d).