Exonuclease 1 (EXO1) (NM_006027) Human Untagged Clone

CAT#: SC124403

EXO1 (untagged)-Human exonuclease 1 (EXO1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXO1
• Synonyms: HEX1; hExoI
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124403 sequence for NM_006027 edited (data generated by NextGen Sequencing)
  ATGGGGATACAGGGATTGCTACAATTTATCAAAGAAGCTTCAGAACCCATCCATGTGAGG
  AAGTATAAAGGGCAGGTAGTAGCTGTGGATACATATTGCTGGCTTCACAAAGGAGCTATT
  GCTTGTGCTGAAAAACTAGCCAAAGGTGAACCTACTGATAGGTATGTAGGATTTTGTATG
  AAATTTGTAAATATGTTACTATCTCATGGGATCAAGCCTATTCTCGTATTTGATGGATGT
  ACTTTACCTTCTAAAAAGGAAGTAGAGAGATCTAGAAGAGAAAGACGACAAGCCAATCTT
  CTTAAGGGAAAGCAACTTCTTCGTGAGGGGAAAGTCTCGGAAGCTCGAGAGTGTTTCACC
  CGGTCTATCAATATCACACATGCCATGGCCCACAAAGTAATTAAAGCTGCCCGGTCTCAG
  GGGGTAGATTGCCTCGTGGCTCCCTATGAAGCTGATGCGCAGTTGGCCTATCTTAACAAA
  GCGGGAATTGTGCAAGCCATAATTACAGAGGACTCGGATCTCCTAGCTTTTGGCTGTAAA
  AAGGTAATTTTAAAGATGGACCAGTTTGGAAATGGACTTGAAATTGATCAAGCTCGGCTA
  GGAATGTGCAGACAGCTTGGGGATGTATTCACGGAAGAGAAGTTTCGTTACATGTGTATT
  CTTTCAGGTTGTGACTACCTGTCATCACTGCGTGGGATTGGATTAGCAAAGGCATGCAAA
  GTCCTAAGACTAGCCAATAATCCAGATATAGTAAAGGTTATCAAGAAAATTGGACATTAT
  CTCAAGATGAATATCACGGTACCAGAGGATTACATCAACGGGTTTATTCGGGCCAACAAT
  ACCTTCCTCTATCAGCTAGTTTTTGATCCCATCAAAAGGAAACTTATTCCTCTGAACGCC
  TATGAAGATGATGTTGATCCTGAAACACTAAGCTACGCTGGGCAATATGTTGATGATTCC
  ATAGCTCTTCAAATAGCACTTGGAAATAAAGATATAAATACTTTTGAACAGATCGATGAC
  TACAATCCAGACACTGCTATGCCTGCCCATTCAAGAAGTCATAGTTGGGATGACAAAACA
  TGTCAAAAGTCAGCTAATGTTAGCAGCATTTGGCATAGGAATTACTCTCCCAGACCAGAG
  TCGGGTACTGTTTCAGATGCCCCACAATTGAAGGAAAATCCAAGTACTGTGGGAGTGGAA
  CGAGTGATTAGTACTAAAGGGTTAAATCTCCCAAGGAAATCATCCATTGTGAAAAGACCA
  AGAAGTGCAGAGCTGTCAGAAGATGACCTGTTGAGTCAGTATTCTCTTTCATTTACGAAG
  AAGACCAAGAAAAATAGCTCTGAAGGCAATAAATCATTGAGCTTTTCTGAAGTGTTTGTG
  CCTGACCTGGTAAATGGACCTACTAACAAAAAGAGTGTAAGCACTCCACCTAGGACGAGA
  AATAAATTTGCAACATTTTTACAAAGGAAAAATGAAGAAAGTGGTGCAGTTGTGGTTCCA
  GGGACCAGAAGCAGGTTTTTTTGCAGTTCAGATTCTACTGACTGTGTATCAAACAAAGTG
  AGCATCCAGCCTCTGGATGAAACTGCTGTCACAGATAAAGAGAACAATCTGCATGAATCA
  GAGTATGGAGACCAAGAAGGCAAGAGACTGGTTGACACAGATGTAGCACGTAATTCAAGT
  GATGACATTCCGAATAATCATATTCCAGGTGATCATATTCCAGACAAGGCAACAGTGTTT
  ACAGATGAAGAGTCCTACTCTTTTGAGAGCAGCAAATTTACAAGGACCATTTCACCACCC
  ACTTTGGGAACACTAAGAAGTTGTTTTAGTTGGTCTGGAGGTCTTGGAGATTTTTCAAGA
  ACGCCGAGCCCCTCTCCAAGCACAGCATTGCAGCAGTTCCGAAGAAAGAGCGATTCCCCC
  ACCTCTTTGCCTGAGAATAATATGTCTGATGTGTCGCAGTTAAAGAGCGAGGAGTCCAGT
  GACGATGAGTCTCATCCCTTACGAGAAGAGGCATGTTCTTCACAGTCCCAGGAAAGTGGA
  GAATTCTCACTGCAGAGTTCAAATGCATCAAAGCTTTCTCAGTGCTCTAGTAAGGACTCT
  GATTCAGAGGAATCTGATTGCAATATTAAGTTACTTGACAGTCAAAGTGACCAGACCTCC
  AAGCTATGTTTATCTCATTTCTCAAAAAAAGACACACCTCTAAGGAACAAGGTTCCTGGG
  CTATATAAGTCCAGTTCTGCAGACTCTCTTTCTACAACCAAGATCAAACCTCTAGGACCT
  GCCAGAGCCAGTGGGCTGAGCAAGAAGCCGGCAAGCATCCAGAAGAGAAAGCATCATAAT
  GCCGAGAACAAGCCGGGGTTACAGATCAAACTCAATGAGCTCTGGAAAAACTTTGGATTT
  AAAAAAGATTCTGAAAAGCTTCCTCCTTGTAAGAAACCCCTGTCCCCAGTCAGAGATAAC
  ATCCAACTAACTCCAGAAGCGGAAGAGGATATATTTAACAAACCTGAATGTGGCCGTGTT
  CAAAGAGCAATATTCCAGTAA
  
  Clone variation with respect to NM_006027.4
  2167 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006027 unedited
  CGGCAACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGAAGCAAGTTA
  CCCGTGTTCTGCGTTGCCGGCCGTGGGTGCTCTGGCCACAGTGAGTTAGGGGCGTCGGAG
  CGGGTTTCTCCAACCGCAATCGGCTCCGCTCAAGGGGAGGAGGAGAGTCCCTTCTCGGAA
  GGCCTAAGGAAACGTGTCGTCTGGAATGGGCTTGGGGGCCACGCCTGCACATCTCCGCGA
  GACAGAGGGATAAAGTGAAGATGGTGCTGTTATTGTTACCTCGAGTGCCACATGCGACCT
  CTGAGATATGTACACAGTCATTCTTACTATCGCACTCAGCCATTCTTACTACGCTAAAGA
  AGAAATAATTATTCGAGGATATTTGCCTGGCCCAGAAGAAACTTATGTAAATTTCATGAA
  CTATTATATCCGTTTTCCTCGGAGTGAGAGAAAACTCTTTTTAGATATCATCTGAGAGCA
  GAACTAGTGAATCCCAGTCACTGAGTGGAGTTGAGAGTCTAAGAACCTCTGAAATTTGAG
  AACTGCTGGACCAGAGCCTTTAGAGCTCTGATAAGGTGTCAACAGGGTAGTTAATTTGGC
  ACCATGGGGATACAGGGATTGCTACAATTTATCAAAGAAGCTTCAGAACCCATCCATGTG
  ANGAAGTATAAAGGGCANGTAGTAGCTGTGGATACATATTGCTGGCTTCACAAAGGAGCT
  ATTGCTTGTGCTGAANAACTAGCCAAAGGTGAACCTACTGATAGGTATGTAGGAATTTGT
  ATGAAATTTGTAATATNGTACTATCTCATGGGATCAAGCCTATTCTCGTATTTGATGGAT
  GTACTTTACCTTCTAAAAAGGAGTNNAGAGATCTANAAGAGAAGACGACAGCCAATCTTC
  TAAGGGAAANGCACNTNCTNCGGAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006027 unedited
  GGTATATCTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAGGCAAAATACAAAATGTTTTCTAT
  TTTTAAAATGGCCCAAAATGAAAAAAAATTCTTCATGCTGATAAGTGCCCCATTCCCAAA
  CAGGGACTTCAAATTGATCAAATTCTCTTGCAGGCAAAAGCTTTGCAGCAGTCTGCATTT
  ACTGGAATATTGCTCTTTGAACACGGCCACATTCAGGTTTGTTAAATATATCCCCTTCCG
  CTTCTGGAGTTAGTTGGATGTTATCTCTGACTGGGGACAGGGGTTTCTTACAAGGAGGAA
  GCTTTTCAAAATCTTTTTTAAATCCAAAGTTTTTCCAGAGCTCATTGAGTTTGATCTGTA
  ACCCCGGCTTGGTCTCGGCATTATGATGCTTTCTCTTCTGGATGCTTGCCGGCTTCTTGC
  TCAACCCACTGGCTCTGGCAGGTCCTAAAGGTTTGATCTTGGTTGTAGAAAGAGAGTCTG
  CANAACTGGACTTATATAGCCCAAGAACCTTGTTCCTTAGAGGTGTGTCTTTTTTTTGAA
  AATGGAGAAAACATAGCTTGAGGTCTGGGCACTTTGCTGGAAGTAACTTAATATGCAATC
  AGATTCCTCTGAATCAAATCCCTTACTAAACACTGGGAAAACTTTGATGCCTTTGAACTC
  TGCGGGAGAAATCCCCCCTTTTCCGGGACGGGAAAAACAAGCCCCTCCTCTAGGGGGAGA
  AACTACACCGCCCTGGGGCTCCCCCTCCTTAACTGGGAAACCTTCAAAATATTTTTCCTC
  CGGCAAAAAGGGGGGGAAATCCTCCTTTCTCCGAAAGGGCGCAAGCTGTGCTGGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006027
• ORF Size: 2541 bp
• Insert Size: 3300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006027.3, NP_006018.3
• RefSeq Size: 3140
• RefSeq ORF: 2541
• Locus ID: 9156
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Mismatch repair
• Gene Summary: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (b). Both variants 1 and 2 encode isoform b.