SEMA6D (NM_020858) Human Untagged Clone

CAT#: SC124440

SEMA6D (untagged)-Human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 1


  "NM_020858" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SEMA6D
Synonyms FLJ11598; KIAA1479
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_020858, the custom clone sequence may differ by one or more nucleotides


ATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCAGCTTTC
CTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACG
CCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTAT
ATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAAACAGAAGTAATACCCAACA
AGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGA
ATGCCACAACTTTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCA
TTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGAATATGATGGGGAAGAAATTAGTGGCCTGG
CAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCAC
AGTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACA
ATAAAATATGATTCCAAATGGATAAAAGAGCCACACTTTCTTCATGCCATAGAATATGGAAACTATGTCT
ATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCGCGTGGCCCG
CATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCT
CGGCTGAACTGTTCTGTCCCTGGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAA
TACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCAATAGCATCCCTGGTTCTGC
TGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCA
GATTCTGTTTGGACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACG
GCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGATGAAACTCTGTCATTCATCAAATCTCATCC
CCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGA
CTGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTG
AAGCTGGCATGGTACTTAAAGTTCTGGCAAAGACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGA
AGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTCATCTCATTA
CAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTC
GCTGTGAGCGTTATGGATCATGTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAG
CCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTGCTGTTAACCGAAGACTTCTTTGCTTTCCATAAC
CACAGTGCTGAAGGATATGAACAAGACACAGAATTCGGCAACACAGCTCATCTAGGGGACTGCCATGGTG
TACGATGGGAAGTCCAGTCTGGAGAGTCCAACCAGATGGTCCACATGAATGTCCTCATCACCTGTGTCTT
TGCTGCTTTTGTTTTGGGGGCATTCATTGCAGGTGTGGCAGTATACTGCTATCGAGACATGTTTGTTCGG
AAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAGTCATGCACAGACTCCAGTGGAAGTTTTGCCA
AACTGAATGGTCTCTTTGACAGCCCTGTCAAGGAATACCAACAGAATATTGATTCTCCTAAACTGTATAG
TAACCTGCTAACCAGTCGGAAAGAGCTACCACCCAATGGAGATACTAAATCCATGGTAATGGACCATCGA
GGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAGTCTACACCCGTGCTTCACCAGAAGACCCTGC
AGGCCATGAAGAGCCACTCAGAAAAGGCCCATGGCCATGGAGCTTCAAGGAAAGAAACCCCTCAGTTTTT
TCCGTCTAGTCCGCCACCTCATTCCCCATTAAGTCATGGGCATATCCCCAGTGCCATTGTTCTTCCAAAT
GCTACCCATGACTACAACACGTCTTTCTCAAACTCCAATGCTCACAAAGCTGAAAAGAAGCTTCAAAACA
TTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATCACCGGCGTTCTGTTGATTCCAGAAATACCCT
CAATGATCTCCTGAAGCATCTGAATGACCCAAATAGTAACCCCAAAGCCATCATGGGAGACATCCAGATG
GCACACCAGAACTTAATGCTGGATCCCATGGGATCGATGTCTGAGGTCCCACCTAAAGTCCCTAACCGGG
AGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAAATAGCCCAACCAAGCGAGTGGATGTCCCCAC
CACTCCTGGAGTCCCAATGACTTCTCTGGAAAGACAAAGAGGTTATCACAAAAATTCCTCCCAGAGGCAC
TCTATATCTGCTATGCCTAAAAACTTAAACTCACCAAATGGTGTTTTGTTATCCAGACAGCCTAGTATGA
ACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGGTGGACTATATTCAGGGAACACCAGTGAGTGT
TCATCTGCAGCCTTCCCTCTCCAGACAGAGCAGCTACACCAGTAATGGCACTCTTCCTAGGACGGGACTA
AAGAGGACGCCGTCCTTAAAACCTGACGTGCCACCAAAGCCTTCCTTTGTTCCTCAAACCCCATCTGTCA
GACCACTGAACAAATACACATACTAG


>OriGene 5' read for NM_020858 unedited
CCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAG
AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA
TTCGGCACGAGGCGGTGCTGAGATGTGTTACGTTCTCATCTCCCCATCAATTATGGATGG
AAACAAATAAGGAAGAGTCAATTTTGCTGAGCCCCTTCTCCGGCAACGAGAGGCGTTCTG
CAGCCGGGAGGGAGCCGCCGCTCGCGCCGGCAGCCGCTGGCAGGGGCATGGTGAGGAGGA
AGGTAGCTCAGTGGCATTTCTGAGCAGGGGCCACCCTGACTTCACCTTGGCCCACCATGA
GGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCA
GCTTTCCTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATC
CGGTTTTTAGAGGACGCCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGA
TGTTGAAAATTCGAGACACACTTTATATTGCTGGCAGGGATCAAGTTTATACAGTAAACT
TAAATGAAATGCCCAAAACAGAAGTAATACCAAACAAGAAACTGACAATGGCGATCAAGA
ACAACAGGATCGAGAAAAACTGTGCTAATGAAAGGCAAGCATAAAGNATGAATGCCACAA
CTTTATCAAGGNTATTTGTTCAAAACATAGNAAGGGTGTNTTTTTTTTGTTTGGGGGCAC
CAATGCATTCATCCCATGTGTATACTTAACGGGGTTGAGACCTAAATAATGAGGGGGGGA
GAAAAATAATTAAGGGCCCTGGCAAGATGCCCANTTGATGCCGACCACCCATGTGCCTCT
TGCTGAGNGNGGAAAGCTGTATCTGCCACATGGCTGGCTTCTGCACGCGAGGGCCGTATT
TCACACGGTGCGGGGGCGGCAGGCCTCTGCCTT
>OriGene 3' read for NM_020858 unedited
CGTGGCGCCATCGGCGATTGGCAACCTCCAGGGCCAGNATGAGCACTGGGGNAGGGTCAC
AGGGCATGCCACCCGGGCACTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGT
CGAGTTTTTTTTTTTGTTTTTTGTTTCTTACCTTGGGGGGTAGGAGGAGTTAAAGGAGGA
GAAATTTTACTATTGGGGGGGGGGGGGAAACNNNCNCNNNNNNNNNNNNNNCNTNNTNNN
GNGNCCNNNGNNNNNNNNNGNGNCNCNNGCNNNGNNNCNCNGCGGNCNGGNNNNTTNNCC
NNCNGCCCCCTGGGCNCCNGNNCNGGGGCCCCNCTTNCCCTCNTGTTCTCCTTNCNCTGG
CNNGCCTGGNTTGCCNGTTTTNNTGNGTNGCNNCNCNNNNTCNCTTGCNNCTCTTNCCTT
CTGGCNTTGGGTCCCNCCTNNGTTCNGTTCCTCNTTTTGNTGGTCNNNNGNNCCTCGNTT
CTNTTCCNCTTTCNNNCCTGNCCCCCNTGGCCTCCTGTGGGNNNTNTTCTTGTCTCTCCT
TCCGTCCTGCTTNCTGTNNCCTTCTCCCTNNCCCNNNNNGTTGCCTTGGGCCCCAGGGCC
NNTCCTNNTTTTTTCNNNNCNCNCTCNCNNCCNNNCNTTTTNNNNTTNNNNCNTCCNNNN
NNCNNTCCCCNCNNNNTTTTTTCTCCTCCCCCCCCCNTTCTTCCCCCCCCTNNNNTNCCN
CTNCNCCCCCTTTNNCCTCCCNNTTTTNNCTTCTNNNCNNCCCCCCCCNNTNNCCNCCCN
TTTCCTTTCCTTTNNNNNTTTTCCCCCCCTTTCTTCTNCCTTTNCNCCNNNNNNCCCCNT
CCCCTTCCCNCCCCCCTNNNCCTCTTCCCCTTTTTNTTTCCCNNCCCCCCCCTTTTTCG
Restriction Sites NotI-NotI     
ACCN NM_020858
ORF Size 3036 bp
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_020858.1, NP_065909.1
RefSeq Size 5923
RefSeq ORF 3036
Locus ID 80031
Protein Families Druggable Genome, Transmembrane
Protein Pathways Axon guidance
Gene Summary Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
Transcript Variant: This variant (1) uses an alternative splice site on one exon and lacks two internal exons, compared to variant 4. The encoded isoform (1) is missing an internal region compared to isoform 4 and contains an internal segment unique to this isoform. Variants

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