SEMA6D (NM_020858) Human Untagged Clone

CAT#: SC124440

SEMA6D (untagged)-Human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEMA6D
• Synonyms: FLJ11598; KIAA1479
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020858, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCAGCTTTC
  CTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACG
  CCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTAT
  ATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAAACAGAAGTAATACCCAACA
  AGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGA
  ATGCCACAACTTTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCA
  TTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGAATATGATGGGGAAGAAATTAGTGGCCTGG
  CAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCAC
  AGTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACA
  ATAAAATATGATTCCAAATGGATAAAAGAGCCACACTTTCTTCATGCCATAGAATATGGAAACTATGTCT
  ATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCGCGTGGCCCG
  CATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCT
  CGGCTGAACTGTTCTGTCCCTGGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAA
  TACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCAATAGCATCCCTGGTTCTGC
  TGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCA
  GATTCTGTTTGGACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACG
  GCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGATGAAACTCTGTCATTCATCAAATCTCATCC
  CCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGA
  CTGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTG
  AAGCTGGCATGGTACTTAAAGTTCTGGCAAAGACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGA
  AGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTCATCTCATTA
  CAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTC
  GCTGTGAGCGTTATGGATCATGTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAG
  CCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTGCTGTTAACCGAAGACTTCTTTGCTTTCCATAAC
  CACAGTGCTGAAGGATATGAACAAGACACAGAATTCGGCAACACAGCTCATCTAGGGGACTGCCATGGTG
  TACGATGGGAAGTCCAGTCTGGAGAGTCCAACCAGATGGTCCACATGAATGTCCTCATCACCTGTGTCTT
  TGCTGCTTTTGTTTTGGGGGCATTCATTGCAGGTGTGGCAGTATACTGCTATCGAGACATGTTTGTTCGG
  AAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAGTCATGCACAGACTCCAGTGGAAGTTTTGCCA
  AACTGAATGGTCTCTTTGACAGCCCTGTCAAGGAATACCAACAGAATATTGATTCTCCTAAACTGTATAG
  TAACCTGCTAACCAGTCGGAAAGAGCTACCACCCAATGGAGATACTAAATCCATGGTAATGGACCATCGA
  GGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAGTCTACACCCGTGCTTCACCAGAAGACCCTGC
  AGGCCATGAAGAGCCACTCAGAAAAGGCCCATGGCCATGGAGCTTCAAGGAAAGAAACCCCTCAGTTTTT
  TCCGTCTAGTCCGCCACCTCATTCCCCATTAAGTCATGGGCATATCCCCAGTGCCATTGTTCTTCCAAAT
  GCTACCCATGACTACAACACGTCTTTCTCAAACTCCAATGCTCACAAAGCTGAAAAGAAGCTTCAAAACA
  TTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATCACCGGCGTTCTGTTGATTCCAGAAATACCCT
  CAATGATCTCCTGAAGCATCTGAATGACCCAAATAGTAACCCCAAAGCCATCATGGGAGACATCCAGATG
  GCACACCAGAACTTAATGCTGGATCCCATGGGATCGATGTCTGAGGTCCCACCTAAAGTCCCTAACCGGG
  AGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAAATAGCCCAACCAAGCGAGTGGATGTCCCCAC
  CACTCCTGGAGTCCCAATGACTTCTCTGGAAAGACAAAGAGGTTATCACAAAAATTCCTCCCAGAGGCAC
  TCTATATCTGCTATGCCTAAAAACTTAAACTCACCAAATGGTGTTTTGTTATCCAGACAGCCTAGTATGA
  ACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGGTGGACTATATTCAGGGAACACCAGTGAGTGT
  TCATCTGCAGCCTTCCCTCTCCAGACAGAGCAGCTACACCAGTAATGGCACTCTTCCTAGGACGGGACTA
  AAGAGGACGCCGTCCTTAAAACCTGACGTGCCACCAAAGCCTTCCTTTGTTCCTCAAACCCCATCTGTCA
  GACCACTGAACAAATACACATACTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020858 unedited
  CCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAG
  AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA
  TTCGGCACGAGGCGGTGCTGAGATGTGTTACGTTCTCATCTCCCCATCAATTATGGATGG
  AAACAAATAAGGAAGAGTCAATTTTGCTGAGCCCCTTCTCCGGCAACGAGAGGCGTTCTG
  CAGCCGGGAGGGAGCCGCCGCTCGCGCCGGCAGCCGCTGGCAGGGGCATGGTGAGGAGGA
  AGGTAGCTCAGTGGCATTTCTGAGCAGGGGCCACCCTGACTTCACCTTGGCCCACCATGA
  GGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCA
  GCTTTCCTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATC
  CGGTTTTTAGAGGACGCCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGA
  TGTTGAAAATTCGAGACACACTTTATATTGCTGGCAGGGATCAAGTTTATACAGTAAACT
  TAAATGAAATGCCCAAAACAGAAGTAATACCAAACAAGAAACTGACAATGGCGATCAAGA
  ACAACAGGATCGAGAAAAACTGTGCTAATGAAAGGCAAGCATAAAGNATGAATGCCACAA
  CTTTATCAAGGNTATTTGTTCAAAACATAGNAAGGGTGTNTTTTTTTTGTTTGGGGGCAC
  CAATGCATTCATCCCATGTGTATACTTAACGGGGTTGAGACCTAAATAATGAGGGGGGGA
  GAAAAATAATTAAGGGCCCTGGCAAGATGCCCANTTGATGCCGACCACCCATGTGCCTCT
  TGCTGAGNGNGGAAAGCTGTATCTGCCACATGGCTGGCTTCTGCACGCGAGGGCCGTATT
  TCACACGGTGCGGGGGCGGCAGGCCTCTGCCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020858 unedited
  CGTGGCGCCATCGGCGATTGGCAACCTCCAGGGCCAGNATGAGCACTGGGGNAGGGTCAC
  AGGGCATGCCACCCGGGCACTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGT
  CGAGTTTTTTTTTTTGTTTTTTGTTTCTTACCTTGGGGGGTAGGAGGAGTTAAAGGAGGA
  GAAATTTTACTATTGGGGGGGGGGGGGAAACNNNCNCNNNNNNNNNNNNNNCNTNNTNNN
  GNGNCCNNNGNNNNNNNNNGNGNCNCNNGCNNNGNNNCNCNGCGGNCNGGNNNNTTNNCC
  NNCNGCCCCCTGGGCNCCNGNNCNGGGGCCCCNCTTNCCCTCNTGTTCTCCTTNCNCTGG
  CNNGCCTGGNTTGCCNGTTTTNNTGNGTNGCNNCNCNNNNTCNCTTGCNNCTCTTNCCTT
  CTGGCNTTGGGTCCCNCCTNNGTTCNGTTCCTCNTTTTGNTGGTCNNNNGNNCCTCGNTT
  CTNTTCCNCTTTCNNNCCTGNCCCCCNTGGCCTCCTGTGGGNNNTNTTCTTGTCTCTCCT
  TCCGTCCTGCTTNCTGTNNCCTTCTCCCTNNCCCNNNNNGTTGCCTTGGGCCCCAGGGCC
  NNTCCTNNTTTTTTCNNNNCNCNCTCNCNNCCNNNCNTTTTNNNNTTNNNNCNTCCNNNN
  NNCNNTCCCCNCNNNNTTTTTTCTCCTCCCCCCCCCNTTCTTCCCCCCCCTNNNNTNCCN
  CTNCNCCCCCTTTNNCCTCCCNNTTTTNNCTTCTNNNCNNCCCCCCCCNNTNNCCNCCCN
  TTTCCTTTCCTTTNNNNNTTTTCCCCCCCTTTCTTCTNCCTTTNCNCCNNNNNNCCCCNT
  CCCCTTCCCNCCCCCCTNNNCCTCTTCCCCTTTTTNTTTCCCNNCCCCCCCCTTTTTCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020858
• ORF Size: 3036 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020858.1, NP_065909.1
• RefSeq Size: 5923
• RefSeq ORF: 3036
• Locus ID: 80031
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• Gene Summary: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (1) uses an alternative splice site on one exon and lacks two internal exons, compared to variant 4. The encoded isoform (1) is missing an internal region compared to isoform 4 and contains an internal segment unique to this isoform. Variants