CHMP2A (NM_198426) Human Untagged Clone

CAT#: SC124538

CHMP2A (untagged)-Human chromatin modifying protein 2A (CHMP2A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHMP2A
• Synonyms: BC-2; BC2; CHMP2; VPS2; VPS2A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124538 sequence for NM_198426 edited (data generated by NextGen Sequencing)
  ATGGACCTATTGTTCGGGCGCCGGAAGACGCCAGAGGAGCTACTGCGGCAGAACCAGAGG
  GCCCTGAACCGTGCCATGCGGGAGCTGGACCGCGAGCGACAGAAACTAGAGACCCAGGAG
  AAGAAAATCATTGCAGACATTAAGAAGATGGCCAAGCAAGGCCAGATGGATGCTGTTCGC
  ATCATGGCAAAAGACTTGGTGCGCACCCGGCGCTATGTGCGCAAGTTTGTATTGATGCGG
  GCCAACATCCAGGCTGTGTCCCTCAAGATCCAGACACTCAAGTCCAACAACTCGATGGCA
  CAAGCCATGAAGGGTGTCACCAAGGCCATGGGCACCATGAACAGACAGCTGAAGTTGCCC
  CAGATCCAGAAGATCATGATGGAGTTTGAGCGGCAGGCAGAGATCATGGATATGAAGGAG
  GAGATGATGAATGATGCCATTGATGATGCCATGGGTGATGAGGAAGATGAAGAGGAGAGT
  GATGCTGTGGTGTCCCAGGTTCTGGATGAGCTGGGACTTAGCCTAACAGATGAGCTGTCG
  AACCTCCCCTCAACTGGGGGCTCGCTTAGTGTGGCTGCTGGTGGGAAAAAAGCAGAGGCC
  GCAGCCTCAGCCCTAGCTGATGCTGATGCAGACCTGGAGGAACGGCTTAAGAACCTGCGG
  AGGGACTGA
  
  Clone variation with respect to NM_198426.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198426 unedited
  ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTTAGTTGGTGGGCAAGTCGG
  GGATCCCAGAAAGAGAAGCGTGACCCGGAAGCGGAAACGGGTGTCCGTCCCAGCTCCGGC
  CTGCCAGTGAGCTTCTACCATCATGGACCTATTGTTCGGGCGCCGGAAGACGCCAGAGGA
  GCTACTGCGGCAGAACCAGAGGGCCCTGAACCGTGCCATGCGGGAGCTGGACCGCGAGCG
  ACAGAAACTAGAGACCCAGGAGAAGAAAATCATTGCAGACATTAAGAAGATGGCCAAGCA
  AGGCCAGATGGATGCTGTTCGCATCATGGCAAAAGACTTGGTGCGCACCCGGCGCTATGT
  GCGCAAGTTTGTATTGATGCGGGCCAACATCCAGGCTGTGTCCCTCAAGATCCAGACACT
  CAAGTCCAACAACTCGATGGCACAAGCCATGAAGGGTGTCACCAAGGCCATGGGCACCAT
  GAACAGACAGCTGAAGTTGCCCCAGATCCAGAAGATCATGATGGAGTTTGAGCGGCAGGC
  AGAGATCATGGATATGAAGGAGGAGATGATGAATGATGCCATTGATGATGCCATGGGTGA
  TGAGGAAGATGAAGAGGAGAGTGATGCTGTGGTGTCCCAGGTTCTGGATGAGCTGGGACT
  TANCCTACAGATGAGCTGTCGAACCTCCCCTCACTGGGGGCTCGCTTAGTGTGGCTGCTG
  GTGGGAAAAAGCANAGCCCGCACCTCAGCCTAGCTGATGCTGATGCAGACCTGGNAGAAA
  CGCTTAGAACCTGCGAGGNACTGANTGCCCCTGCCACTCGAGATACCAGTGGATGCCNCA
  GATCTTNTACCACANCCCTCTGTATAAAAGAGATTGACACTAAAAAAAAAAAAAAAACTC
  ACTCTGTATGCGGCGGGTCTAGCTGTTCTGAAAAAACCGGTTGATCCCTGGACCCTCCCA
  GGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_198426
• ORF Size: 669 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_198426.1, NP_940818.1
• RefSeq Size: 928
• RefSeq ORF: 669
• Locus ID: 27243
• Protein Pathways: Endocytosis
• Gene Summary: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.