Aurora A (AURKA) (NM_198434) Human Untagged Clone

CAT#: SC124640

AURKA (untagged)-Human aurora kinase A (AURKA), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AURKA
• Synonyms: AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_198434, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCGATCTAAAGAAAACTGCATTTCAGGACCTGTTAAGGCTACAGCTCCAGTTGGAGGTCCAAAAC
  GTGTTCTCGTGACTCAGCAATTTCCTTGTCAGAATCCATTACCTGTAAATAGTGGCCAGGCTCAGCGGGT
  CTTGTGTCCTTCAAATTCTTCCCAGCGCATTCCTTTGCAAGCACAAAAGCTTGTCTCCAGTCACAAGCCG
  GTTCAGAATCAGAAGCAGAAGCAATTGCAGGCAACCAGTGTACCTCATCCTGTCTCCAGGCCACTGAATA
  ACACCCAAAAGAGCAAGCAGCCCCTGCCATCGGCACCTGAAAATAATCCTGAGGAGGAACTGGCATCAAA
  ACAGAAAAATGAAGAATCAAAAAAGAGGCAGTGGGCTTTGGAAGACTTTGAAATTGGTCGCCCTCTGGGT
  AAAGGAAAGTTTGGTAATGTTTATTTGGCAAGAGAAAAGCAAAGCAAGTTTATTCTGGCTCTTAAAGTGT
  TATTTAAAGCTCAGCTGGAGAAAGCCGGAGTGGAGCATCAGCTCAGAAGAGAAGTAGAAATACAGTCCCA
  CCTTCGGCATCCTAATATTCTTAGACTGTATGGTTATTTCCATGATGCTACCAGAGTCTACCTAATTCTG
  GAATATGCACCACTTGGAACAGTTTATAGAGAACTTCAGAAACTTTCAAAGTTTGATGAGCAGAGAACTG
  CTACTTATATAACAGAATTGGCAAATGCCCTGTCTTACTGTCATTCGAAGAGAGTTATTCATAGAGACAT
  TAAGCCAGAGAACTTACTTCTTGGATCAGCTGGAGAGCTTAAAATTGCAGATTTTGGGTGGTCAGTACAT
  GCTCCATCTTCCAGGAGGACCACTCTCTGTGGCACCCTGGACTACCTGCCCCCTGAAATGATTGAAGGTC
  GGATGCATGATGAGAAGGTGGATCTCTGGAGCCTTGGAGTTCTTTGCTATGAATTTTTAGTTGGGAAGCC
  TCCTTTTGAGGCAAACACATACCAAGAGACCTACAAAAGAATATCACGGGTTGAATTCACATTCCCTGAC
  TTTGTAACAGAGGGAGCCAGGGACCTCATTTCAAGACTGTTGAAGCATAATCCCAGCCAGAGGCCAATGC
  TCAGAGAAGTACTTGAACACCCCTGGATCACAGCAAATTCATCAAAACCATCAAATTGCCAAAACAAAGA
  ATCAGCTAGCAAACAGTCTTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198434 unedited
  TTGTCAATACGCACTNCACTTATAGGGNCGGCCCGCGCAATTCGGCACGCAGGGAAGACT
  TGGGTCCTTGGGTCGCAGGGTCTCACTCCATTGCCCAGGCCAGAGTGCGGGGATATTTGA
  TAAGAAACTTTAGTGAAGGCCGGGCGCGGTGGCTCATGCCCGTAATCCCAGCATTTTCGG
  AGGCCGAGGCATCATGGACCGATCTAAAGAAAACTGCATTTCAGGACCTGCTAAGGCTAC
  AGCTCCAGCTGGAGGCCCAAAACGTGTTCTCGTGACTCACCAATTTCCTTGTCAGAATCC
  ATTACCTGTAAATAGTGGCCAGGCTCAGCGGGCCTTGTGTCCTTCAAATTCTTCCCAGCG
  CATTCCTTTGCAAGCACAAAAGCTTGCCTCCAGTTACAAGTCGGCTCACAATCACAAGCA
  CAAGCAATCGCAGGCCACCACTGTACCTCATCCTGTCTCCAGGCCCACTGAATACCACCC
  AAAAGAGCAAGCAGCCCCCTGCCATCGGCACCTGAAAATAATTCTGAGGCAGGAACTGGC
  ATCCAAACCAGAACAATGATCAATCATACCCCAGGCAGCGGGCTTTGGAAGACTTTGCAA
  TTGGCCCCCCCTCTGCCCAAAAGGAAAGTTTGGTAATGTTCTATCTGGCCCCGAAAACCG
  CACACGTACGTTTCACCTCGCCTCTTAACGCGCCATTTAACCGCCCACTTGGAGAAAAGC
  TGGATTGCAGTATCCCCCTTACAAAGAGCAATCCCAATTCCCGCTCCCCCCTCTCGGGAT
  CTCTACTAATTCCCAACACCGGTCCCGGCTATCTTCCATGGACGCTACCCAGAAGTTTAC
  CCTATTTTCTGGCAAATTGCCCCACCTTGGAAACCCTTTAATAAACGACCCTACCAAAAC
  ACTTTTAAAAGCTCCAGGAAATAACACACCCTGATACCTCACCCAACCCCCATTGGCATA
  ATGCCCCTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_198434
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_198434.1, NP_940836.1
• RefSeq Size: 2245 bp
• RefSeq ORF: 1212 bp
• Locus ID: 6790
• Cytogenetics: 20q13.2
• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Oocyte meiosis
• Gene Summary: 'The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-9 encode the same protein.