Cytohesin 2 (CYTH2) (NM_004228) Human Untagged Clone

CAT#: SC124671

CYTH2 (untagged)-Human cytohesin 2 (CYTH2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYTH2
• Synonyms: ARNO; CTS18; CTS18.1; cytohesin-2; PSCD2; PSCD2L; SEC7L; Sec7p-L; Sec7p-like
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004228, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGACGGCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGATGGAGCTGGAGAACATCCGGC
  GGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGCGGGAGGAGCTCAGTGAAGCCATGAGCGAGGT
  GGAGGGGCTGGAGGCCAATGAGGGCAGTAAGACCTTGCAACGGAACCGGAAGATGGCAATGGGCAGGAAG
  AAGTTCAACATGGACCCCAAGAAGGGGATCCAGTTCTTGGTGGAGAATGAACTGCTGCAGAACACACCCG
  AGGAGATCGCCCGCTTCCTGTACAAGGGCGAGGGGCTGAACAAGACAGCCATCGGGGACTACCTGGGGGA
  GAGGGAAGAACTGAACCTGGCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCGACCTCAATCTG
  GTGCAGGCCCTCAGGCAGTTTCTATGGAGCTTTCGCCTACCCGGAGAGGCCCAGAAAATTGACCGGATGA
  TGGAGGCCTTCGCCCAGCGATACTGCCTGTGCAACCCTGGGGTTTTCCAGTCCACAGACACGTGCTATGT
  GCTGTCCTTCGCCGTCATCATGCTCAACACCAGTCTCCACAATCCCAATGTCCGGGACAAGCCGGGCCTG
  GAGCGCTTTGTGGCCATGAACCGGGGCATCAACGAGGGCGGGGACCTGCCTGAGGAGCTGCTCAGGAACC
  TGTACGACAGCATCCGAAATGAGCCCTTCAAGATTCCTGAGGATGACGGGAATGACCTGACCCACACCTT
  CTTCAACCCGGACCGGGAGGGCTGGCTCCTGAAGCTGGGGGGCCGGGTGAAGACGTGGAAGCGGCGCTGG
  TTTATCCTCACAGACAACTGCCTCTACTACTTTGAGTACACCACGGACAAGGAGCCCCGAGGAATCATCC
  CCCTGGAGAATCTGAGCATCCGAGAGGTGGACGACCCCCGGAAACCGAACTGCTTTGAACTTTACATCCC
  CAACAACAAGGGGCAGCTCATCAAAGCCTGCAAAACTGAGGCGGACGGCCGAGTGGTGGAGGGAAACCAC
  ATGGTGTACCGGATCTCGGCCCCCACGCAGGAGGAGAAGGACGAGTGGATCAAGTCCATCCAGGCGGCTG
  TGAGTGTGGACCCCTTCTATGAGATGCTGGCAGCGAGAAAGAAGCGGATTTCAGTCAAGAAGAAGCAGGA
  GCAGCCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004228 unedited
  CGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACCAGGAGGAGGCGG
  CGGTGGCTCCCGGGGCGTTTGAGCGGGCTCACCCGAGCCCGCGGGCCAACGCGGATCCAG
  GCCCGACTGGCGGGACCGCCCCGGATTCCCCGCGGGCCTTCCTAGCCGCCATGGAGGACG
  GCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGATGGAGCTGGAGAACATCCGGC
  GGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGCGGGAGGAGCTCAGTGAAGCCA
  TGAGCGAGGTGGAGGGGCTGGAGGCCAATGAGGGCAGTAAGACCTTGCAACGGAACCGGA
  AGATGGCAATGGGCAGGAAGAAGTTCAACATGGACCCCAAGAAGGGGATCCAGTTCTTGG
  TGGAGAATGAACTGCTGCAGAACACACCCGAGGAGATCGCCCGCTTCCTGTACAAGGGCG
  AGGGGCTGAACAAGACAGCCATCGGGGCCTACCCTGGGGGAGAGGGAAGAACTGAACCTG
  GCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCGACCTCAATCTGGTGCAGGCC
  CTCANGCAGTTTCTATGGAGNCTTCGCCTACCCGGAGAGGCCCCAGAAATTGACCGGATG
  ATGGNAGGCCTTCGCCCAGCGATACTGCCTGTGCACCCTGGGGGTTTTCAGTCACAGACC
  GTGCTTTGTGCTGTCTTCGCCTCATATGCTCACACCGTCTCACATCCCATGTCCGGACAG
  GCGGCCTGAGCGCTTTGTGGCATGACCGGGCATCACGAGGCCGGGACTGNCTGAGAGCTG
  TCAGGAACCTGTCACAGATCGAATGAGCCTCAGATCTGAGGAGACGGGAAGACTGACCAC
  ACTTTTAACGCCGGAAGGTGTCCTAAATGGAGGGGGCCCCGGAAAAAGGAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004228
• ORF Size: 1200 bp
• Insert Size: 1800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004228.4, NP_004219.2
• RefSeq Size: 4622
• RefSeq ORF: 1200
• Locus ID: 9266
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  Transcript Variant: This variant (2) lacks a 3-nucleotide exon in the PH domain region, compared to variant 1. This results in a protein (isoform 2) missing a single glycine residue, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.