NIRF (UHRF2) (NM_152896) Human Untagged Clone

CAT#: SC124707

UHRF2 (untagged)-Human ubiquitin-like with PHD and ring finger domains 2 (UHRF2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UHRF2
• Synonyms: NIRF; RNF107; TDRD23; URF2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124707 sequence for NM_152896 edited (data generated by NextGen Sequencing)
  ATGTGGATACAGGTTCGCACCATTGATGGCTCCAAGACGTGCACCATTGAGGACGTGTCT
  CGCAAAGCCACGATTGAGGAGCTGCGCGAGCGGGTGTGGGCGCTGTTCGACGTGCGGCCC
  GAATGCCAGCGCCTCTTCTACCGGGGCAAGCAGTTGGAAAATGGATATACCTTATTTGAT
  TATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT
  CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAG
  AAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATT
  GATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTT
  GGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGT
  GGCAAAACTCCACTGAAGAATGGCAGTTCTTGTAAAAGGACTAATGGAAATATAAAGCAT
  AAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGT
  GTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGT
  ACTCTAGAAATGAATGTCAAGGATCTTAGACCACGAGCTAGAACCATTTTGAAATGGAAT
  GAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGA
  GGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAA
  CTTCGTGTGAAAATTTTCCTGGGGGGTTCTGAAGGAACATTAAATGACTGCAAGATAATA
  TCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGAT
  GGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAG
  AAATGTCATTCTTGCTCCTGTCGTGTATGTGGTGGGAAACATGAACCCAACATGCAGCTT
  CTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAA
  GTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTA
  AAGGCTGGTGAAAGACTCAAGATGAGTAAAAAGAAAGCAAAGATGCCGTCAGCTAGTACT
  GAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACT
  ATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGA
  TTTAGAGTTCAGGTGAGCGAAGCAGGTGTTCACAGACCCCATGTTGGTGGAATTCATGGT
  CGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGAC
  CGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGA
  ATTGGTGCACCTTCAGCTGATCAAACATTAACAAACATGAACAGGGCATTGGCCCTAAAC
  TGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAG
  CCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAA
  GGCAACAGATATGATGGCATTTATAAGGTGGTGAAATACTGGCCAGAGATTTCATCAAGC
  CATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGG
  ACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGT
  TACCCTTCAGATAAAGAAGGGAAGAAGCCTAAAGGACAGTCAAAGAAGCAGCCCAGTGGA
  ACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCA
  TCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATC
  AGAGAAGATTGTCAAAACCAGAAGCTGTGGGATGAAGTGCTTTCACATCTTGTGGAAGGA
  CCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTT
  TACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGTCTACAGCGCTCC
  TTTAAGGCACAGGTTTTCTCCTGCCCTGCTTGCCGGCATGATCTTGGCCAGAATTACATC
  ATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAA
  GGACGATGA
  
  Clone variation with respect to NM_152896.2
  2268 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152896 unedited
  ACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGGCGCGGCGCAGACATGGCCTCTTCC
  TATCTTTGAGGCGGTGTCTGCGGCAGCGCCTCAGAGTGGTTCCGGTCGTCTCTCCTCAAG
  TCGGCTAGTCGGGCGCGCGCGCTGAGAGTCGTCGCCGCCTGTCGGGCCCGGCGTCCGGTC
  GGTCCGGTGGGCGCGCTCGCCCGCCTGCCGCTGAGGGCCCGAGCCGCAGGGAAAGCGGCG
  CGGGCCGGGCGGGGCGCGGCGCCCAGAGCTCAGGGGGAGACAAAGGGGACCGGTTCCTCT
  CTAGGCGCCAAGATGTGGATACAGGTTCGCACCATTGATGGCTCCAAGACGTGCACCATT
  GAGGACGTGTCTCGCAAAGCCACGATTGAGGAGCTGCGCGAGCGGGTGTGGGCGCTGTTC
  GACGTGCGGCCCGAATGCCAGCGCCTCTTCTACCGGGGCAAGCAGTTGGAAAATGGATAT
  ACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGAC
  CCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCA
  CCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGT
  GCCCGTCTTATTGATCCTGGCTNTGGATATATAAGGTAAATGAATTGGTGGATGCCANAG
  ATGTCGCCTTGGTGCTTGGTTTGAAGCCACATACATAGTGGTACTANAGCTTCTGATGGA
  CAGTCACGTGGCAAAACTCCACTGAGAAAGGCAGGTTCTGGAAAAGGACTAATGGAAATT
  TTAAGCTTAATTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152896
• ORF Size: 2409 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152896.1, NP_690856.1
• RefSeq Size: 3621
• RefSeq ORF: 2409
• Locus ID: 115426
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (1) represents the shorter transcript.