PTPRD (NM_130392) Human Untagged Clone

CAT#: SC124818

PTPRD (untagged)-Human protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 3


  "NM_130392" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PTPRD
Synonyms HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC124818 sequence for NM_130392 edited (data generated by NextGen Sequencing)
ATGGTGCACGTAGCCAGGCTGCTGCTGCTGCTCCTCACTTTCTTCCTCCGCACGGATGCT
GAGACACCTCCAAGGTTTACACGAACACCCGTTGATCAGACAGGGGTCTCTGGCGGAGTT
GCCTCTTTCATCTGCCAAGCTACGGGAGACCCAAGACCTAAAATTGTCTGGAACAAAAAA
GGAAAGAAAGTCAGCAATCAGAGATTTGAGGTAATAGAGTTTGACGATGGGTCTGGATCA
GTTCTCAGAATACAACCCTTACGGACTCCGAGGGATGAGGCCATTTATGAATGTGTGGCC
TCAAATAATGTGGGAGAAATAAGTGTATCCACCAGACTCACAGTTTTGCGGGAAGATCAA
ATTCCCAGGGGCTTCCCTACCATTGACATGGGCCCACAGTTGAAGGTGGTTGAGCGTACT
CGCACGGCCACCATGCTTTGTGCAGCCAGTGGTAATCCGGATCCAGAAATCACTTGGTTT
AAAGATTTCTTACCTGTGGACACAAGCAACAACAATGGTCGTATTAAGCAGTTACGATCA
GAATCTATTGGTGGTACACCAATAAGAGGAGCCCTTCAGATTGAGCAGAGTGAAGAGTCT
GACCAAGGAAAATATGAGTGTGTTGCCACCAACAGCGCGGGCACTCGCTATTCCGCTCCT
GCCAATTTATATGTCAGAGAGCTGCGAGAAGTTCGCCGTGTCCCACCAAGATTCTCTATC
CCACCCACTAATCATGAAATCATGCCAGGCGGAAGCGTTAATATCACCTGTGTGGCCGTG
GGGTCACCAATGCCTTATGTAAAGTGGATGTTGGGGGCAGAAGATCTGACACCTGAAGAT
GATATGCCAATAGGAAGAAATGTGCTAGAACTGAATGATGTAAGACAGTCAGCAAATTAC
ACCTGTGTTGCTATGTCAACACTGGGTGTCATTGAAGCAATAGCACAGATCACTGTCAAA
GCCTTACCCAAACCTCCAGGAACTCCTGTAGTGACCGAGAGCACAGCTACAAGCATCACA
CTGACGTGGGACTCTGGGAACCCTGAGCCTGTTTCTTATTACATAATTCAGCATAAACCT
AAAAACTCTGAGGAACTTTACAAAGAAATTGATGGGGTGGCGACCACACGCTACAGTGTC
GCTGGACTAAGTCCCTACTCGGATTATGAATTCAGGGTTGTTGCTGTCAATAACATTGGG
CGGGGGCCTCCCAGCGAACCTGTGCTAACACAAACCTCAGAGCAAGCACCATCCAGTGCC
CCGAGGGATGTCCAGGCACGAATGTTGAGTTCGACCACCATTTTGGTACAGTGGAAGGAA
CCTGAAGAGCCAAATGGACAGATCCAAGGATATAGAGTTTATTATACAATGGATCCCACT
CAACATGTCAACAACTGGATGAAACACAATGTAGCTGACAGCCAAATCACTACTATTGGC
AACTTAGTGCCCCAGAAAACATATTCTGTCAAAGTCCTGGCTTTTACCTCAATTGGAGAT
GGTCCCCTTTCAAGTGACATACAAGTCATCACTCAGACAGGAGTACCAGGGCAGCCACTA
AACTTCAAAGCAGAACCTGAGTCTGAAACAAGTATTTTGCTCTCTTGGACACCTCCACGT
TCAGATACCATTGCCAACTATGAACTGGTCTACAAAGATGGGGAGCATGGAGAGGAGCAA
CGAATTACCATTGAGCCAGGGACATCATATAGGCTGCAAGGACTGAAACCAAACAGCTTA
TACTATTTCCGTCTGGCTGCACGCTCCCCTCAAGGCCTGGGTGCTTCTACTGCAGAAATA
TCAGCTAGAACCATGCAGTCAATGTTTGCAAAAAATTTTCATGTCAAAGCAGTAATGAAG
ACTTCCGTGTTGCTGTCTTGGGAGATTCCAGAGAATTATAACTCCGCCATGCCTTTCAAA
ATTCTTTATGATGATGGGAAAATGGTAGAAGAAGTGGATGGCCGAGCCACACAGAAGTTA
ATTGTCAACCTGAAGCCTGAGAAATCATATTCATTTGTGCTGACAAATCGTGGAAACAGT
GCTGGTGGGCTGCAGCACAGGGTCACGGCAAAGACTGCACCAGATGTATTACGTACCAAG
CCTGCCTTCATTGGGAAGACCAACTTGGATGGCATGATTACTGTGCAACTGCCTGAAGTA
CCTGCAAATGAGAATATAAAAGGTTACTACATAATAATTGTGCCTTTGAAGAAATCTCGC
GGGAAATTTATCAAGCCATGGGAGAGTCCAGATGAAATGGAATTAGATGAGCTGCTTAAG
GAGATATCTAGGAAGCGCAGAAGCATCCGTTATGGGAGAGAAGTTGAATTAAAGCCATAT
ATTGCCGCTCACTTTGATGTCCTTCCCACTGAGTTCACCCTGGGGGATGACAAGCATTAT
GGTGGATTTACAAACAAGCAACTCCAAAGTGGTCAAGAATATGTCTTCTTTGTGTTAGCA
GTAATGGAACATGCAGAGTCTAAGATGTATGCAACCAGCCCTTACTCCGACCCCGTGGTG
TCAATGGATCTGGATCCGCAGCCAATCACGGATGAAGAAGAAGGCTTGATCTGGGTTGTA
GGTCCTGTCCTTGCAGTGGTCTTTATCATCTGCATTGTCATTGCTATTCTTCTTTATAAA
AGNNNTAAACCCGACAGGAAGAGGGCAGAGTCCGACTCTAGAAAAAGCAGCATACCGAAC
AATAAGGAGATCCCTTCACACCACCCAACAGACCCTGTAGAACTGAGGCGCCTTAACTTT
CAAACACCGGGTATGGCTAGCCATCCTCCAATACCCATCTTGGAACTTGCAGACCACATT
GAAAGATTGAAAGCAAATGACAACTTGAAGTTTTCCCAGGAATATGAGTCAATTGACCCT
GGCCAGCAGTTCACTTGGGAACATTCAAACTTGGAAGTAAACAAACCAAAGAATAGATAC
GCGAATGTAATCGCATATGATCATTCCCGGGTTCTCCTATCAGCTATAGAAGGGATCCCA
GGAAGTGACTATGTGAATGCCAACTACATAGATGGCTATAGGAAGCAAAATGCCTATATT
GCAACACAGGGATCTCTCCCCGAAACATTTGGGGACTTTTGGAGAATGATATGGGAACAA
CGGAGTGCCACAGTTGTCATGATGACAAAACTAGAAGAAAGATCAAGGGTGAAGTGTGAC
CAGTATTGGCCTAGCAGAGGCACAGAAACCCACGGACTCGTTCAAGTAACGCTGCTTGAT
ACTGTGGAGCTGGCCACATATTGTGTTCGAACATTTGCACTTTACAAGAATGGTTCAAGT
GAGAAGAGAGAAGTGAGACAATTCCAGTTCACCGCCTGGCCTGATCATGGTGTTCCAGAA
CACCCTACACCTTTTCTAGCTTTCTTACGTAGAGTCAAAACCTGTAACCCTCCCGATGCT
GGTCCGATGGTTGTGCACTGCAGTGCGGGAGTTGGCCGGACTGGTTGCTTCATCGTCATA
GATGCCATGTTAGAAAGAATAAAGCATGAAAAAACTGTAGATATTTATGGCCATGTAACT
TTAATGAGAGCCCAGAGGAACTATATGGTTCAAACAGAAGACCAATACATCTTTATCCAT
GATGCACTGTTAGAAGCAGTGACTTGTGGAAATACCGAAGTGCCAGCTAGAAACTTGTAT
GCCTACATTCAGAAGCTGACACAAATAGAAACGGGAGAGAATGTCACAGGAATGGAGCTC
GAATTTAAGCGTCTAGCCAGCTCAAAAGCTCACACCTCAAGGTTTATCAGTGCCAATCTT
CCATGTAATAAATTCAAAAATCGCCTTGTTAATATTATGCCATATGAATCCACAAGGGTA
TGCCTGCAGCCTATCCGTGGAGTAGAAGGATCTGATTACATCAATGCCAGTTTTATTGAT
GGATACAGACAACAGAAAGCCTACATCGCTACCCAGGGGCCCTTGGCAGAGACCACTGAA
GACTTCTGGCGGATGCTCTGGGAACACAATTCCACCATAGTTGTGATGCTCACCAAGCTG
CGTGAAATGGGCAGAGAGAAATGTCACCAATACTGGCCAGCAGAACGGTCTGCAAGATAC
CAGTACTTTGTTGTAGATCCCATGGCTGAGTACAACATGCCACAGTATATCCTAAGGGAA
TTCAAGGTCACAGATGCCAGGGACGGCCAGTCCCGAACAGTAAGGCAGTTCCAGTTCACT
GACTGGCCAGAGCAAGGAGTGCCAAAGTCCGGAGAAGGATTTATTGACTTCATCGGCCAA
GTCCATAAAACAAAAGAACAGTTTGGCCAAGATGGACCCATTTCAGTCCATTGCAGCGCG
GGCGTTGGAAGAACTGGAGTCTTCATAACGCTAAGCATTGTTTTGGAAAGAATGAGATAT
GAAGGAGTTGTAGATATCTTCCAGACTGTCAAAATGTTAAGAACACAACGACCAGCTATG
GTACAGACAGAGGATCAATATCAGTTTTCCTATCGTGCCGCACTAGAGTACCTGGGCAGC
TTTGACCACTATGCAACGTAG

Clone variation with respect to NM_130392.3
2643 c=>n;2644 a=>n;2645 g=>n;3036 g=>c
>OriGene 5' read for NM_130392 unedited
NTAAGTCAGGATTTGTAAACGACTCACTATAGGGCGGCCGCCGAATTCCCACCAGGAAAA
GCAAGCAGTTCCTGNCCCCTNAGATTGATGGGGAGGGGTCTNACTAACAACATGTTGGCA
CCGAGGGAAGCGATGGGCTTCCGCTCCAGGTTTCTGTGCTGAGACCACAGCAGAATGTGC
CTTGGGCAAAGGCTTGGGCTCCTTGATCTTCTGGGGACTTCAAAAATCTGGTCTCAGGGG
GGGGAGGGGGGTGTGTTCCAATTCCTAACCTGTGAGCTTACCATGATGGGGCCTGTGCAT
TAACTGAACAACTGTGGTTTTGAACTTCTTGAGGCCAGGGACTGTGTCTGAAAACACCGA
CCGGGGGTAACTCAAGGGAGACGTCTGGTGAACACCCGTGGGATCTAAAGAACAAGCTCT
GAAAGTGTGCCAGCTGAAATTTCAAATCCGACAGACTCGCTGCGGCTCCGGAGGCANTGA
TTCCAAGCTGCTCCCGCACGCTGCTGCCAAGCTGCANGATGGTGCACNTANCCAGGCTGC
TGCTGCTGCTCCTCACTTTCTTCCTCCGGACGATGCTGAGACACCTCCAAGGTTACACCA
ACACCCGTTNATCANACAGGGGTCTCTGGCGGAGTTGCCTCTTTCATCTGCCAAGCGTAC
GGAGACCCAAGACCTAAAATTGTGCTGGAGCAAAAAAAGAGAGAAAGTCAGCAATCAGAG
ATTTGAGGGAATAAAGTTTNACCATGGGGCCTGGATCACTTCTCAAAATACAACCCTTAC
CGACTCCTAGGGGAGGAGGCCATTTATGAAAGTGGGGCCTCAAATATGTGGGAGAAATAA
ATGTATCCACCACACTCACCGTTTTCGCGGGAAATCAAAATCCCAGGGGC
>OriGene 3' read for NM_130392 unedited
TTCAGCTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTGTG
GTAAACAGATAATGCTTTAATAGAAAGTAACAGATACGAACAGTGAATGGAAATACGAAC
CAAAAGCTAAAAAGAAATGCTATTAAAATAGGCATCAATTATAAGGCACTCTAAATGCAA
AACTAAAACCAAAACGAAACAAAGTACAGCACTTCCCAGGAATGCTGTATGCCACAAAAT
GTTTCTGACTGAACAGAGTAACATGAATTTGGCTTTGCCCCTGTTACGTATCATAAATGC
AAATTTCATAGCACATACTATAGACAATATACGATTGAATACACTTTTTTTTAACAACTC
GATAGCCTGATTATTACACCTTCTCCCCTCCTAAAGGGAAATCCCTGGACCTTTCCCATT
GCCCCCCCTTTACCCTTTAAAAAAAATTTTATGGCCCAAAAGGTAAAAAAATTTAACTTT
GGTGAAACCCTGGTTAAAAAAAAAAAAAAAAATTTGGAAAAAAATATTTGGAAGGGGGGG
GAAATTATGGGGAAAAAAAGGGGGGGGGGGGTTTCCACAAAAACCGGGGGGGGGGGTTCC
CTTTTTTCCTTTATAAAAAACCCCCTGGTGAAAAAAAATAAAAAAAAGGGGGGGGGGGGG
GGGTGTTCCCANGTTTTTTTTTTCTTTAAAAAAAAAAAACTTTGTTGGAAAAAACACCGC
GGNNNNNCTTTTTTTTTTTTTTTTGGGGGGGGCCCCCCCCTTTTTTAATTA
Restriction Sites NotI-NotI     
ACCN NM_130392
Insert Size 8000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_130392.1, NP_569076.1
RefSeq Size 6236 bp
RefSeq ORF 5712 bp
Locus ID 5789
Cytogenetics 9p24.1-p23
Domains Y_phosphatase, ig, PTPc_motif, IGc2, IG, FN3
Protein Families Druggable Genome, Phosphatase, Transmembrane
Gene Summary 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]'
Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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