PTPRD (NM_130392) Human Untagged Clone

CAT#: SC124818

PTPRD (untagged)-Human protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRD
• Synonyms: HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124818 sequence for NM_130392 edited (data generated by NextGen Sequencing)
  ATGGTGCACGTAGCCAGGCTGCTGCTGCTGCTCCTCACTTTCTTCCTCCGCACGGATGCT
  GAGACACCTCCAAGGTTTACACGAACACCCGTTGATCAGACAGGGGTCTCTGGCGGAGTT
  GCCTCTTTCATCTGCCAAGCTACGGGAGACCCAAGACCTAAAATTGTCTGGAACAAAAAA
  GGAAAGAAAGTCAGCAATCAGAGATTTGAGGTAATAGAGTTTGACGATGGGTCTGGATCA
  GTTCTCAGAATACAACCCTTACGGACTCCGAGGGATGAGGCCATTTATGAATGTGTGGCC
  TCAAATAATGTGGGAGAAATAAGTGTATCCACCAGACTCACAGTTTTGCGGGAAGATCAA
  ATTCCCAGGGGCTTCCCTACCATTGACATGGGCCCACAGTTGAAGGTGGTTGAGCGTACT
  CGCACGGCCACCATGCTTTGTGCAGCCAGTGGTAATCCGGATCCAGAAATCACTTGGTTT
  AAAGATTTCTTACCTGTGGACACAAGCAACAACAATGGTCGTATTAAGCAGTTACGATCA
  GAATCTATTGGTGGTACACCAATAAGAGGAGCCCTTCAGATTGAGCAGAGTGAAGAGTCT
  GACCAAGGAAAATATGAGTGTGTTGCCACCAACAGCGCGGGCACTCGCTATTCCGCTCCT
  GCCAATTTATATGTCAGAGAGCTGCGAGAAGTTCGCCGTGTCCCACCAAGATTCTCTATC
  CCACCCACTAATCATGAAATCATGCCAGGCGGAAGCGTTAATATCACCTGTGTGGCCGTG
  GGGTCACCAATGCCTTATGTAAAGTGGATGTTGGGGGCAGAAGATCTGACACCTGAAGAT
  GATATGCCAATAGGAAGAAATGTGCTAGAACTGAATGATGTAAGACAGTCAGCAAATTAC
  ACCTGTGTTGCTATGTCAACACTGGGTGTCATTGAAGCAATAGCACAGATCACTGTCAAA
  GCCTTACCCAAACCTCCAGGAACTCCTGTAGTGACCGAGAGCACAGCTACAAGCATCACA
  CTGACGTGGGACTCTGGGAACCCTGAGCCTGTTTCTTATTACATAATTCAGCATAAACCT
  AAAAACTCTGAGGAACTTTACAAAGAAATTGATGGGGTGGCGACCACACGCTACAGTGTC
  GCTGGACTAAGTCCCTACTCGGATTATGAATTCAGGGTTGTTGCTGTCAATAACATTGGG
  CGGGGGCCTCCCAGCGAACCTGTGCTAACACAAACCTCAGAGCAAGCACCATCCAGTGCC
  CCGAGGGATGTCCAGGCACGAATGTTGAGTTCGACCACCATTTTGGTACAGTGGAAGGAA
  CCTGAAGAGCCAAATGGACAGATCCAAGGATATAGAGTTTATTATACAATGGATCCCACT
  CAACATGTCAACAACTGGATGAAACACAATGTAGCTGACAGCCAAATCACTACTATTGGC
  AACTTAGTGCCCCAGAAAACATATTCTGTCAAAGTCCTGGCTTTTACCTCAATTGGAGAT
  GGTCCCCTTTCAAGTGACATACAAGTCATCACTCAGACAGGAGTACCAGGGCAGCCACTA
  AACTTCAAAGCAGAACCTGAGTCTGAAACAAGTATTTTGCTCTCTTGGACACCTCCACGT
  TCAGATACCATTGCCAACTATGAACTGGTCTACAAAGATGGGGAGCATGGAGAGGAGCAA
  CGAATTACCATTGAGCCAGGGACATCATATAGGCTGCAAGGACTGAAACCAAACAGCTTA
  TACTATTTCCGTCTGGCTGCACGCTCCCCTCAAGGCCTGGGTGCTTCTACTGCAGAAATA
  TCAGCTAGAACCATGCAGTCAATGTTTGCAAAAAATTTTCATGTCAAAGCAGTAATGAAG
  ACTTCCGTGTTGCTGTCTTGGGAGATTCCAGAGAATTATAACTCCGCCATGCCTTTCAAA
  ATTCTTTATGATGATGGGAAAATGGTAGAAGAAGTGGATGGCCGAGCCACACAGAAGTTA
  ATTGTCAACCTGAAGCCTGAGAAATCATATTCATTTGTGCTGACAAATCGTGGAAACAGT
  GCTGGTGGGCTGCAGCACAGGGTCACGGCAAAGACTGCACCAGATGTATTACGTACCAAG
  CCTGCCTTCATTGGGAAGACCAACTTGGATGGCATGATTACTGTGCAACTGCCTGAAGTA
  CCTGCAAATGAGAATATAAAAGGTTACTACATAATAATTGTGCCTTTGAAGAAATCTCGC
  GGGAAATTTATCAAGCCATGGGAGAGTCCAGATGAAATGGAATTAGATGAGCTGCTTAAG
  GAGATATCTAGGAAGCGCAGAAGCATCCGTTATGGGAGAGAAGTTGAATTAAAGCCATAT
  ATTGCCGCTCACTTTGATGTCCTTCCCACTGAGTTCACCCTGGGGGATGACAAGCATTAT
  GGTGGATTTACAAACAAGCAACTCCAAAGTGGTCAAGAATATGTCTTCTTTGTGTTAGCA
  GTAATGGAACATGCAGAGTCTAAGATGTATGCAACCAGCCCTTACTCCGACCCCGTGGTG
  TCAATGGATCTGGATCCGCAGCCAATCACGGATGAAGAAGAAGGCTTGATCTGGGTTGTA
  GGTCCTGTCCTTGCAGTGGTCTTTATCATCTGCATTGTCATTGCTATTCTTCTTTATAAA
  AGNNNTAAACCCGACAGGAAGAGGGCAGAGTCCGACTCTAGAAAAAGCAGCATACCGAAC
  AATAAGGAGATCCCTTCACACCACCCAACAGACCCTGTAGAACTGAGGCGCCTTAACTTT
  CAAACACCGGGTATGGCTAGCCATCCTCCAATACCCATCTTGGAACTTGCAGACCACATT
  GAAAGATTGAAAGCAAATGACAACTTGAAGTTTTCCCAGGAATATGAGTCAATTGACCCT
  GGCCAGCAGTTCACTTGGGAACATTCAAACTTGGAAGTAAACAAACCAAAGAATAGATAC
  GCGAATGTAATCGCATATGATCATTCCCGGGTTCTCCTATCAGCTATAGAAGGGATCCCA
  GGAAGTGACTATGTGAATGCCAACTACATAGATGGCTATAGGAAGCAAAATGCCTATATT
  GCAACACAGGGATCTCTCCCCGAAACATTTGGGGACTTTTGGAGAATGATATGGGAACAA
  CGGAGTGCCACAGTTGTCATGATGACAAAACTAGAAGAAAGATCAAGGGTGAAGTGTGAC
  CAGTATTGGCCTAGCAGAGGCACAGAAACCCACGGACTCGTTCAAGTAACGCTGCTTGAT
  ACTGTGGAGCTGGCCACATATTGTGTTCGAACATTTGCACTTTACAAGAATGGTTCAAGT
  GAGAAGAGAGAAGTGAGACAATTCCAGTTCACCGCCTGGCCTGATCATGGTGTTCCAGAA
  CACCCTACACCTTTTCTAGCTTTCTTACGTAGAGTCAAAACCTGTAACCCTCCCGATGCT
  GGTCCGATGGTTGTGCACTGCAGTGCGGGAGTTGGCCGGACTGGTTGCTTCATCGTCATA
  GATGCCATGTTAGAAAGAATAAAGCATGAAAAAACTGTAGATATTTATGGCCATGTAACT
  TTAATGAGAGCCCAGAGGAACTATATGGTTCAAACAGAAGACCAATACATCTTTATCCAT
  GATGCACTGTTAGAAGCAGTGACTTGTGGAAATACCGAAGTGCCAGCTAGAAACTTGTAT
  GCCTACATTCAGAAGCTGACACAAATAGAAACGGGAGAGAATGTCACAGGAATGGAGCTC
  GAATTTAAGCGTCTAGCCAGCTCAAAAGCTCACACCTCAAGGTTTATCAGTGCCAATCTT
  CCATGTAATAAATTCAAAAATCGCCTTGTTAATATTATGCCATATGAATCCACAAGGGTA
  TGCCTGCAGCCTATCCGTGGAGTAGAAGGATCTGATTACATCAATGCCAGTTTTATTGAT
  GGATACAGACAACAGAAAGCCTACATCGCTACCCAGGGGCCCTTGGCAGAGACCACTGAA
  GACTTCTGGCGGATGCTCTGGGAACACAATTCCACCATAGTTGTGATGCTCACCAAGCTG
  CGTGAAATGGGCAGAGAGAAATGTCACCAATACTGGCCAGCAGAACGGTCTGCAAGATAC
  CAGTACTTTGTTGTAGATCCCATGGCTGAGTACAACATGCCACAGTATATCCTAAGGGAA
  TTCAAGGTCACAGATGCCAGGGACGGCCAGTCCCGAACAGTAAGGCAGTTCCAGTTCACT
  GACTGGCCAGAGCAAGGAGTGCCAAAGTCCGGAGAAGGATTTATTGACTTCATCGGCCAA
  GTCCATAAAACAAAAGAACAGTTTGGCCAAGATGGACCCATTTCAGTCCATTGCAGCGCG
  GGCGTTGGAAGAACTGGAGTCTTCATAACGCTAAGCATTGTTTTGGAAAGAATGAGATAT
  GAAGGAGTTGTAGATATCTTCCAGACTGTCAAAATGTTAAGAACACAACGACCAGCTATG
  GTACAGACAGAGGATCAATATCAGTTTTCCTATCGTGCCGCACTAGAGTACCTGGGCAGC
  TTTGACCACTATGCAACGTAG
  
  Clone variation with respect to NM_130392.3
  2643 c=>n;2644 a=>n;2645 g=>n;3036 g=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130392 unedited
  NTAAGTCAGGATTTGTAAACGACTCACTATAGGGCGGCCGCCGAATTCCCACCAGGAAAA
  GCAAGCAGTTCCTGNCCCCTNAGATTGATGGGGAGGGGTCTNACTAACAACATGTTGGCA
  CCGAGGGAAGCGATGGGCTTCCGCTCCAGGTTTCTGTGCTGAGACCACAGCAGAATGTGC
  CTTGGGCAAAGGCTTGGGCTCCTTGATCTTCTGGGGACTTCAAAAATCTGGTCTCAGGGG
  GGGGAGGGGGGTGTGTTCCAATTCCTAACCTGTGAGCTTACCATGATGGGGCCTGTGCAT
  TAACTGAACAACTGTGGTTTTGAACTTCTTGAGGCCAGGGACTGTGTCTGAAAACACCGA
  CCGGGGGTAACTCAAGGGAGACGTCTGGTGAACACCCGTGGGATCTAAAGAACAAGCTCT
  GAAAGTGTGCCAGCTGAAATTTCAAATCCGACAGACTCGCTGCGGCTCCGGAGGCANTGA
  TTCCAAGCTGCTCCCGCACGCTGCTGCCAAGCTGCANGATGGTGCACNTANCCAGGCTGC
  TGCTGCTGCTCCTCACTTTCTTCCTCCGGACGATGCTGAGACACCTCCAAGGTTACACCA
  ACACCCGTTNATCANACAGGGGTCTCTGGCGGAGTTGCCTCTTTCATCTGCCAAGCGTAC
  GGAGACCCAAGACCTAAAATTGTGCTGGAGCAAAAAAAGAGAGAAAGTCAGCAATCAGAG
  ATTTGAGGGAATAAAGTTTNACCATGGGGCCTGGATCACTTCTCAAAATACAACCCTTAC
  CGACTCCTAGGGGAGGAGGCCATTTATGAAAGTGGGGCCTCAAATATGTGGGAGAAATAA
  ATGTATCCACCACACTCACCGTTTTCGCGGGAAATCAAAATCCCAGGGGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_130392 unedited
  TTCAGCTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTGTG
  GTAAACAGATAATGCTTTAATAGAAAGTAACAGATACGAACAGTGAATGGAAATACGAAC
  CAAAAGCTAAAAAGAAATGCTATTAAAATAGGCATCAATTATAAGGCACTCTAAATGCAA
  AACTAAAACCAAAACGAAACAAAGTACAGCACTTCCCAGGAATGCTGTATGCCACAAAAT
  GTTTCTGACTGAACAGAGTAACATGAATTTGGCTTTGCCCCTGTTACGTATCATAAATGC
  AAATTTCATAGCACATACTATAGACAATATACGATTGAATACACTTTTTTTTAACAACTC
  GATAGCCTGATTATTACACCTTCTCCCCTCCTAAAGGGAAATCCCTGGACCTTTCCCATT
  GCCCCCCCTTTACCCTTTAAAAAAAATTTTATGGCCCAAAAGGTAAAAAAATTTAACTTT
  GGTGAAACCCTGGTTAAAAAAAAAAAAAAAAATTTGGAAAAAAATATTTGGAAGGGGGGG
  GAAATTATGGGGAAAAAAAGGGGGGGGGGGGTTTCCACAAAAACCGGGGGGGGGGGTTCC
  CTTTTTTCCTTTATAAAAAACCCCCTGGTGAAAAAAAATAAAAAAAAGGGGGGGGGGGGG
  GGGTGTTCCCANGTTTTTTTTTTCTTTAAAAAAAAAAAACTTTGTTGGAAAAAACACCGC
  GGNNNNNCTTTTTTTTTTTTTTTTGGGGGGGGCCCCCCCCTTTTTTAATTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130392
• Insert Size: 8000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_130392.1, NP_569076.1
• RefSeq Size: 6236 bp
• RefSeq ORF: 5712 bp
• Locus ID: 5789
• Cytogenetics: 9p24.1-p23
• Domains: Y_phosphatase, ig, PTPc_motif, IGc2, IG, FN3
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]'
  Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.