PDCD10 (NM_145859) Human Untagged Clone

CAT#: SC124860

PDCD10 (untagged)-Human programmed cell death 10 (PDCD10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDCD10
• Synonyms: CCM3; TFAR15
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC124860 sequence for NM_145859 edited (data generated by NextGen Sequencing)
  ATGAGGATGACAATGGAAGAGATGAAGAATGAAGCTGAGACCACATCCATGGTTTCTATG
  CCCCTCTATGCAGTCATGTATCCTGTGTTTAATGAGCTAGAACGAGTAAATCTGTCTGCA
  GCCCAGACACTGAGAGCCGCTTTCATCAAGGCTGAAAAAGAAAATCCAGGTCTCACACAA
  GACATCATTATGAAAATTTTAGAGAAAAAAAGCGTGGAAGTTAACTTCACGGAGTCCCTT
  CTTCGTATGGCAGCTGATGATGTAGAAGAGTATATGATTGAACGACCAGAGCCAGAATTC
  CAAGACCTAAACGAAAAGGCACGAGCACTTAAACAAATTCTCAGTAAGATCCCAGATGAG
  ATCAATGACAGAGTGAGGTTTCTGCAGACAATCAAGGATATAGCTAGTGCAATAAAAGAA
  CTTCTTGATACAGTGAATAATGTCTTCAAGAAATATCAATACCAGAACCGCAGGGCACTT
  GAACACCAAAAGAAAGAATTTGTAAAGTACTCCAAAAGTTTCAGTGATACTCTGAAAACG
  TATTTTAAAGATGGCAAGGCAATAAATGTGTTCGTAAGTGCCAACCGACTAATTCATCAA
  ACCAACTTAATACTTCAGACCTTCAAAACTGTGGCCTGA
  
  Clone variation with respect to NM_145859.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145859 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGTTGAAGAGGGC
  TGCAAGGTGGGAAGTGAAGTCAGTGCCTCAGTTGCTGATCAGTGTGTTTTTTGTGTCCAA
  TTCTTTTATCACCAAAAAAGAGAAGAAATATTGCAGTGAATGAAGATTCCTCTGCATTTT
  AGCACTGCTTTTTCAACTGTAGTTGGCTTTTGAATGAGGATGACAATGGAAGAGATGAAG
  AATGAAGCTGAGACCACATCCATGGTTTCTATGCCCCTCTATGCAGTCATGTATCCTGTG
  TTTAATGAGCTAGAACGAGTAAATCTGTCTGCAGCCCAGACACTGAGAGCCGCTTTCATC
  AAGGCTGAAAAAGAAAATCCAGGTCTCACACAAGACATCATTATGAAAATTTTAGAGAAA
  AAAAGCGTGGAAGTTAACTTCACGGAGTCCCTTCTTCGTATGGCAGCTGATGATGTAGAA
  GAGTATATGATTGAACGACCAGAGCCAGAATTCCAAGACCTAAACGAAAAGGCACGAGCA
  CTTAAACAAATTCTCAGTAAGATCCCAGATGAGATCAATGACAGAGTGAGGTTTCTGCAG
  ACAATCAAGGATATAGCTAGTGCAATAAAAGAACTTCTTGATACAGTGAATAATGTCTTC
  AAGAATATCAATACCAGACCGCAGGNCACTTGAACACCAANAGAAAGAATNNTGTAAGTA
  CTCCAAAAGTTTCAGTGATACTCTGAAAACGTATTTTAAAGATGGGCAGGGCATANNATG
  TGTCGTAAGTGCCAACCGACTAATNCATCANNACCACTTANTACTTCAGACCTTCAAACT
  GNTGCCTGAAAGTGTTATGTTAAGAGATGACTCTCAGTGCAGTATTGACTGCCTTATCTG
  TAANTNTAAGNTTGACTGATAANTATCAGTCCTNCTGAGGNATCTATNCAGNATGTGATG
  GGATATTGCATCTACACATATTTGTAAAGTAGCTATCTATCTCACGAGATTGCTACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_145859
• ORF Size: 639 bp
• Insert Size: 1550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_145859.1, NP_665858.1
• RefSeq Size: 1313
• RefSeq ORF: 639
• Locus ID: 11235
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform.