Angiopoietin like 4 (ANGPTL4) (NM_139314) Human Untagged Clone

CAT#: SC125038

ANGPTL4 (untagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANGPTL4
• Synonyms: ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125038 sequence for NM_139314 edited (data generated by NextGen Sequencing)
  ATGAGCGGTGCTCCGACGGCCGGGGCAGCCCTGATGCTCTGCGCCGCCACCGCCGTGCTA
  CTGAGCGCTCAGGGCGGACCCGTGCAGTCCAAGTCGCCGCGCTTTGCGTCCTGGGACGAG
  ATGAATGTCCTGGCGCACGGACTCCTGCAGCTCGGCCAGGGGCTGCGCGAACACGCGGAG
  CGCACCCGCAGTCAGCTGAGCGCGCTGGAGCGGCGCCTGAGCGCGTGCGGGTCCGCCTGT
  CAGGGAACCGAGGGGTCCACCGACCTCCCGTTAGCCCCTGAGAGCCGGGTGGACCCTGAG
  GTCCTTCACAGCCTGCAGACACAACTCAAGGCTCAGAACAGCAGGATCCAGCAACTCTTC
  CACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGAAGCAGCACCTGCGAATTCAGCATCTG
  CAAAGCCAGTTTGGCCTCCTGGACCACAAGCACCTAGACCATGAGGTGGCCAAGCCTGCC
  CGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAGTTGACCCGGCTCACAATGTCAGCCGC
  CTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGTTCCAGGTTGGGGAGAGGCAGAGTGGA
  CTATTTGAAATCCAGCCTCAGGGGTCTCCGCCATTTTTGGTGAACTGCAAGATGACCTCA
  GATGGAGGCTGGACAGTAATTCAGAGGCGCCACGATGGCTCAGTGGACTTCAACCGGCCC
  TGGGAAGCCTACAAGGCGGGGTTTGGGGATCCCCACGGCGAGTTCTGGCTGGGTCTGGAG
  AAGGTGCATAGCATCACGGGGGACCGCAACAGCCGCCTGGCCGTGCAGCTGCGGGACTGG
  GATGGCAACGCCGAGTTGCTGCAGTTCTCCGTGCACCTGGGTGGCGAGGACACGGCCTAT
  AGCCTGCAGCTCACTGCACCCGTGGCCGGCCAGCTGGGCGCCACCACCGTCCCACCCAGC
  GGCCTCTCCGTACCCTTCTCCACTTGGGACCAGGATCACGACCTCCGCAGGGACAAGAAC
  TGCGCCAAGAGCCTCTCTGGAGGCTGGTGGTTTGGCACCTGCAGCCATTCCAACCTCAAC
  GGCCAGTACTTCCGCTCCATCCCACAGCAGCGGCAGAAGCTTAAGAAGGGAATCTTCTGG
  AAGACCTGGCGGGGCCGCTACTACCCGCTGCAGGCCACCACCATGTTGATCCAGCCCATG
  GCAGCAGAGGCAGCCTCCTAG
  
  Clone variation with respect to NM_139314.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139314 unedited
  NGGGGTTCAGATTTGTATACGACTCATATAGGCGGACCGCGAATTCGCACCAGCGGNATC
  CTCACACGACTGTGATCCGATTCTTTCCAGCGGCTTCTGCAACCAAGCGGGTCTTACCCC
  CGGTCCTCCGCGTCTCCAGTCCTCGCACCTGGAACCCCAACGTCCCCGAGAGTCCCCGAA
  TCCCCGCTCCCAGGCTACCTAAGAGGATGAGCGGTGCTCCGACGGCCGGGGCAGCCCTGA
  TGCTCTGCGCCGCCACCGCCGTGCTACTGAGCGCTCAGGGCGGACCCGTGCAGTCCAAGT
  CGCCGCGCTTTGCGTCCTGGGACGAGATGAATGTCCTGGCGCACGGACTCCTGCAGCTCG
  GCCAGGGGCTGCGCGAACACGCGGAGCGCACCCGCAGTCAGCTGAGCGCGCTGGAGCGGC
  GCCTGAGCGCGTGCGGGTCCGCCTGTCAGGGAACCGAGGGGTCCACCGACCTCCCGTTAG
  CCCCTGAGAGCCGGGTGGACCCTGAGGTCCTTCACAGCCTGCAGACACAACTCAAGGCTC
  AGAACAGCAGGATCCAGCAACTCTTCCACAAGGTGGCCCAGCAGCAGCGGCACCTGGAGA
  AGCAGCACCTGCGAATTCAGCATCTGCAAAGCCAGTTTGGCCTCCTGGACCACAAGCACC
  TAGACCATGAGGTGGCCAAGCCTGCCCGAAGAAAGAGGCTGCCCGAGATGGCCCAGCCAG
  TTGACCCGGCTCACAATGTCAGCCGCCTGCACCGGCTGCCCAGGGATTGCCAGGAGCTGT
  TCCAGGTTGGGGAGAAGCANAGTGGACTATTTGAAATCCAGCCTCAGGGGTCTCCGCCAT
  TTTTGGTGAACTGCAAGATGACCTCANATGGAGGCTGGACAGTAATTCAGAGGCGCCACG
  ATGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139314 unedited
  TTTACTAGACTCGCGGCCGCAATCTAAGATCGATTTTTTTTTTTTTTTTTTGTTCTGAGG
  TTGCTTTTATTCCAAAAACTCTGTGAGCTCCGCCCAAAACCATTGGCGCCTGCTTGTGGC
  CCCAGGGGACCTACACACAACAGCACCAGCACCATGAGGGCGCTCTCGACCCACACAAAC
  CCTGGTCCCCGTCAGTCAATGTGACTGAGTCCGCCATTGAGGCCAGTCTGGCTGGCCCCA
  AGTGGTCCCTCTGAGTCCCCAACTCCCTGGCCAGCAAGGAGTGAAGCTACATGCCATTTG
  ACGCACGCCTCTAGAGTCAGAGCATATCCTGACGGGCATATTTTTAGAAGCGGGGGGGGG
  AGATTCGATGAACGGAAAAAAGGGGCCACAGGAGTGGTCGTCTTCTTGCCTGGCCGAAAG
  GGTACCGGATGAGCGGTGCGTGGAGGCCCTGGAAAACAGGTAACGGCGACGTCCCGGGGC
  GCCGGAACGTCTATCATCGATAAAGCCCCTAAAAACAGGCACATCGAGAGCATGGGGGCG
  GCCATTGCCGACTCCGGGCGGATCTAGAAGATTGGGACAAAATGTAGAGAAGGGACGGAG
  GGGGAGGAACATAAAATAAGGACGAGGGCACACCAGAAAGAGCATGCCCCCGCCCCTTTC
  CGCCGCGCGGGGTACGATTGGGCACATTTCATCATACTTACGGACGGCAAGATGTGGTTG
  TCGCGTTGTCGGCGCGGGTGATTATGCCGAGAATCCGAAGTGGCATAAGTGCCGAAAGAT
  GCGAGTATAGAGGGGGCAGCAGCTCAGTGGATACAGAGCGTGTGGCCTGAGCCCGATGGT
  TGTAACGACGGGTAGACGGTCGCAGCGTTGAAAATAGGCACAAATATCGGGGGCGCATCT
  GAATCGTGCGGTAGACAGCGGACACCTACATGAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139314
• ORF Size: 1221 bp
• Insert Size: 1800
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_139314.1, NP_647475.1
• RefSeq Size: 1967
• RefSeq ORF: 1221
• Locus ID: 51129
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: PPAR signaling pathway
• Gene Summary: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).